NBIX
Price
$134.97
Change
+$1.48 (+1.11%)
Updated
Jul 17, 02:51 PM (EDT)
Capitalization
13.72B
13 days until earnings call
OPK
Price
$1.41
Change
+$0.04 (+2.94%)
Updated
Jul 17, 02:53 PM (EDT)
Capitalization
920.03M
14 days until earnings call
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NBIX vs OPK

Header iconNBIX vs OPK Comparison
Open Charts NBIX vs OPKBanner chart's image
Neurocrine Biosciences
Price$134.97
Change+$1.48 (+1.11%)
Volume$100
Capitalization13.72B
OPKO Health
Price$1.41
Change+$0.04 (+2.94%)
Volume$825
Capitalization920.03M
NBIX vs OPK Comparison Chart in %
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NBIX
Daily Signalchanged days ago
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OPK
Daily Signalchanged days ago
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NBIX vs. OPK commentary
Jul 17, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is NBIX is a Hold and OPK is a Buy.

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COMPARISON
Comparison
Jul 17, 2025
Stock price -- (NBIX: $133.48 vs. OPK: $1.36)
Brand notoriety: NBIX and OPK are both not notable
NBIX represents the Pharmaceuticals: Other, while OPK is part of the Medical Specialties industry
Current volume relative to the 65-day Moving Average: NBIX: 86% vs. OPK: 63%
Market capitalization -- NBIX: $13.72B vs. OPK: $920.03M
NBIX [@Pharmaceuticals: Other] is valued at $13.72B. OPK’s [@Medical Specialties] market capitalization is $920.03M. The market cap for tickers in the [@Pharmaceuticals: Other] industry ranges from $77.48B to $0. The market cap for tickers in the [@Medical Specialties] industry ranges from $3.82T to $0. The average market capitalization across the [@Pharmaceuticals: Other] industry is $3.81B. The average market capitalization across the [@Medical Specialties] industry is $8.62B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

NBIX’s FA Score shows that 0 FA rating(s) are green whileOPK’s FA Score has 0 green FA rating(s).

  • NBIX’s FA Score: 0 green, 5 red.
  • OPK’s FA Score: 0 green, 5 red.
According to our system of comparison, NBIX is a better buy in the long-term than OPK.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

NBIX’s TA Score shows that 4 TA indicator(s) are bullish while OPK’s TA Score has 7 bullish TA indicator(s).

  • NBIX’s TA Score: 4 bullish, 4 bearish.
  • OPK’s TA Score: 7 bullish, 2 bearish.
According to our system of comparison, OPK is a better buy in the short-term than NBIX.

Price Growth

NBIX (@Pharmaceuticals: Other) experienced а -0.02% price change this week, while OPK (@Medical Specialties) price change was -1.45% for the same time period.

The average weekly price growth across all stocks in the @Pharmaceuticals: Other industry was -2.02%. For the same industry, the average monthly price growth was +5.49%, and the average quarterly price growth was +72.55%.

The average weekly price growth across all stocks in the @Medical Specialties industry was -1.35%. For the same industry, the average monthly price growth was +1.87%, and the average quarterly price growth was -1.26%.

Reported Earning Dates

NBIX is expected to report earnings on Nov 04, 2025.

OPK is expected to report earnings on Nov 05, 2025.

Industries' Descriptions

@Pharmaceuticals: Other (-2.02% weekly)

Pharmaceuticals (Other) comprise companies that are involved in the discovery, development or manufacturing of therapeutic and preventative medicines. They often collaborate with or acquire other pharmaceutical/healthcare firms. Examples of companies in this segment include Bausch Health Companies Inc., Icon Plc and Perrigo Company Plc.

@Medical Specialties (-1.35% weekly)

Medical specialties are companies that make equipment used by the health care industry. Equipment manufactured and distributed by these companies include dialysis machines, blood analysis equipment, surgical equipment, dental instruments, and diagnostic tools, among other items. Large companies typically aim to produce and distribute high-quality products across a broad market spectrum. Smaller firms are more likely to specialize in a particular market segment. Due to the industry’s close association with medical treatments, they typically have low sensitivity to macroeconomic fluctuations. Within this industry, Abbott Laboratories, Medtronic Plc and Thermo Fisher Scientific Inc. are some of the companies with multi-billion market capitalizations in the U.S. stock markets.

SUMMARIES
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FUNDAMENTALS
Fundamentals
NBIX($13.7B) has a higher market cap than OPK($920M). NBIX has higher P/E ratio than OPK: NBIX (57.20) vs OPK (26.11). NBIX YTD gains are higher at: -2.212 vs. OPK (-7.483). NBIX has higher annual earnings (EBITDA): 358M vs. OPK (-65.52M). NBIX has more cash in the bank: 1.03B vs. OPK (95.9M). OPK has less debt than NBIX: OPK (327M) vs NBIX (428M). NBIX has higher revenues than OPK: NBIX (1.89B) vs OPK (863M).
NBIXOPKNBIX / OPK
Capitalization13.7B920M1,489%
EBITDA358M-65.52M-546%
Gain YTD-2.212-7.48330%
P/E Ratio57.2026.11219%
Revenue1.89B863M219%
Total Cash1.03B95.9M1,076%
Total Debt428M327M131%
FUNDAMENTALS RATINGS
NBIX vs OPK: Fundamental Ratings
NBIX
OPK
OUTLOOK RATING
1..100
7181
VALUATION
overvalued / fair valued / undervalued
1..100
72
Overvalued
67
Overvalued
PROFIT vs RISK RATING
1..100
82100
SMR RATING
1..100
6190
PRICE GROWTH RATING
1..100
5077
P/E GROWTH RATING
1..100
3498
SEASONALITY SCORE
1..100
n/an/a

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

OPK's Valuation (67) in the Biotechnology industry is in the same range as NBIX (72). This means that OPK’s stock grew similarly to NBIX’s over the last 12 months.

NBIX's Profit vs Risk Rating (82) in the Biotechnology industry is in the same range as OPK (100). This means that NBIX’s stock grew similarly to OPK’s over the last 12 months.

NBIX's SMR Rating (61) in the Biotechnology industry is in the same range as OPK (90). This means that NBIX’s stock grew similarly to OPK’s over the last 12 months.

NBIX's Price Growth Rating (50) in the Biotechnology industry is in the same range as OPK (77). This means that NBIX’s stock grew similarly to OPK’s over the last 12 months.

NBIX's P/E Growth Rating (34) in the Biotechnology industry is somewhat better than the same rating for OPK (98). This means that NBIX’s stock grew somewhat faster than OPK’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
NBIXOPK
RSI
ODDS (%)
Bearish Trend 2 days ago
57%
N/A
Stochastic
ODDS (%)
Bearish Trend 2 days ago
61%
Bearish Trend 2 days ago
79%
Momentum
ODDS (%)
Bullish Trend 2 days ago
69%
Bullish Trend 2 days ago
77%
MACD
ODDS (%)
Bullish Trend 2 days ago
69%
Bullish Trend 2 days ago
80%
TrendWeek
ODDS (%)
Bearish Trend 2 days ago
61%
Bearish Trend 2 days ago
81%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
72%
Bullish Trend 2 days ago
72%
Advances
ODDS (%)
Bullish Trend 8 days ago
72%
Bullish Trend 9 days ago
74%
Declines
ODDS (%)
Bearish Trend 21 days ago
62%
Bearish Trend 3 days ago
80%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
77%
Bullish Trend 2 days ago
82%
Aroon
ODDS (%)
Bullish Trend 2 days ago
74%
Bullish Trend 2 days ago
73%
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NBIX
Daily Signalchanged days ago
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OPK
Daily Signalchanged days ago
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NBIX and

Correlation & Price change

A.I.dvisor tells us that NBIX and LFCR have been poorly correlated (+33% of the time) for the last year. This A.I.-generated data suggests there is low statistical probability that NBIX and LFCR's prices will move in lockstep.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To NBIX
1D Price
Change %
NBIX100%
+1.71%
LFCR - NBIX
33%
Poorly correlated
-0.13%
EOLS - NBIX
30%
Poorly correlated
-0.76%
ELAN - NBIX
30%
Poorly correlated
-0.68%
CGC - NBIX
29%
Poorly correlated
+0.92%
TLRY - NBIX
27%
Poorly correlated
+1.58%
More

OPK and

Correlation & Price change

A.I.dvisor indicates that over the last year, OPK has been loosely correlated with ICUI. These tickers have moved in lockstep 41% of the time. This A.I.-generated data suggests there is some statistical probability that if OPK jumps, then ICUI could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To OPK
1D Price
Change %
OPK100%
+2.26%
ICUI - OPK
41%
Loosely correlated
-1.31%
ZIMV - OPK
39%
Loosely correlated
-1.36%
CRL - OPK
35%
Loosely correlated
+0.34%
XAIR - OPK
35%
Loosely correlated
+2.53%
CLPT - OPK
34%
Loosely correlated
+1.61%
More