PFE
Price
$25.21
Change
-$0.71 (-2.74%)
Updated
Jun 18 closing price
Capitalization
143.68B
45 days until earnings call
Intraday BUY SELL Signals
SNY
Price
$42.38
Change
-$0.12 (-0.28%)
Updated
Jun 18 closing price
Capitalization
101B
40 days until earnings call
Intraday BUY SELL Signals
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PFE vs SNY

PFE vs SNY Comparison Chart in %
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Which Stock Would AI Choose? Pfizer Inc. (PFE) vs. Sanofi (SNY) Stock Comparison

Key Takeaways

  • PFE has outperformed SNY year-to-date with approximately 12% gains compared to SNY's modest 1.5% rise, driven by oncology pipeline advancements.
  • Both stocks trade at similar forward P/E ratios (price-to-earnings) around 20, indicating comparable valuations in the pharmaceutical sector.
  • PFE's market capitalization exceeds $156 billion, larger than SNY's $115 billion, reflecting broader global exposure.
  • Recent weeks show SNY gaining about 6% over the past month versus PFE's 2%, buoyed by immunology approvals.
  • PFE benefits from momentum in weight loss and cancer treatments, while SNY focuses on Dupixent expansions.
  • Tickeron's AI analysis leans toward PFE for superior trend consistency and growth catalysts in recent market activity.

Introduction

Pharmaceutical giants PFE (Pfizer Inc.) and SNY (Sanofi) represent cornerstone holdings in healthcare portfolios, offering exposure to innovative drugs, vaccines, and chronic disease treatments. This comparison evaluates their recent stock performance, business drivers, and market positioning amid shifting sector dynamics like oncology breakthroughs and immunology expansions. Traders seeking momentum plays and long-term investors eyeing dividend stability will find value in understanding their relative strengths, especially as both navigate post-pandemic revenue transitions and pipeline developments in recent market activity.

PFE Overview and Recent Performance

Pfizer Inc. (PFE), a leading biopharmaceutical company, specializes in vaccines, oncology, and internal medicine, with blockbuster products like Prevnar and ongoing COVID-19 therapeutics. In recent weeks, PFE shares have hovered around $27.50, up over 10% year-to-date and 33% over the past year, outperforming broader indices. This momentum stems from positive analyst initiations, such as CICC's Outperform rating, and pipeline progress including a Priority Review for PADCEV plus Keytruda in bladder cancer and potential Lyme disease vaccine advancements. Sentiment has improved despite COVID sales declines, fueled by explorations into obesity treatments challenging established GLP-1 leaders, enhancing long-term growth prospects.

SNY Overview and Recent Performance

Sanofi (SNY), a diversified global healthcare firm, excels in immunology, rare diseases, and consumer health, anchored by Dupixent collaborations with Regeneron. Shares trade near $48, with about 1.5% year-to-date gains and roughly 6% monthly appreciation in recent market activity, reflecting stability amid volatility. Key influences include EU approvals for Dupixent in pediatric urticaria and expansions into radiopharmaceuticals via partnerships like Telix. Upcoming Q1 2026 earnings on April 23 add anticipation, while collaborations in oncology, AI-driven discovery, and protein degradation bolster pipeline diversity. Investor sentiment remains steady, supported by consistent dividend payouts despite modest YTD returns.

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Head-to-Head Comparison

Both PFE and SNY operate in the large-cap pharmaceutical space, but diverge in focus: PFE emphasizes vaccines and oncology amid pipeline diversification, while SNY prioritizes immunology via Dupixent and rare disease therapies. Growth drivers contrast with PFE's obesity and cancer catalysts versus SNY's partnership-driven approvals. Recent momentum favors PFE on YTD basis, though SNY shows short-term strength. Risk factors include patent cliffs for both, but PFE faces steeper COVID revenue drops. Sector exposure is similar in healthcare, yet PFE garners stronger market sentiment from U.S.-centric innovations.

Tickeron AI Verdict

Tickeron’s AI models currently favor PFE over SNY, citing superior year-to-date trend consistency, oncology momentum, and relative valuation stability. While SNY offers defensive positioning through diversified partnerships, PFE's catalysts like potential weight loss entries provide higher probabilistic upside in prevailing conditions.

Disclaimer

The information on this webpage is provided for general informational and educational purposes only and is not intended as investment advice, a recommendation to purchase or sell any security, or an offer or solicitation related to investments. It does not consider your personal financial situation, goals, or risk profile, and all investing carries inherent risks, including the possibility of losing your entire investment. For more details, please review our full disclaimer. Disclaimers and Limitations

VS
PFE vs. SNY commentary
Jun 20, 2026

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is PFE is a Hold and SNY is a Hold.

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COMPARISON
Comparison
Jun 20, 2026
Stock price -- (PFE: $25.21 vs. SNY: $42.38)
Brand notoriety: PFE: Notable vs. SNY: Not notable
Both companies represent the Pharmaceuticals: Major industry
Current volume relative to the 65-day Moving Average: PFE: 328% vs. SNY: 148%
Market capitalization -- PFE: $143.68B vs. SNY: $101B
PFE [@Pharmaceuticals: Major] is valued at $143.68B. SNY’s [@Pharmaceuticals: Major] market capitalization is $101B. The market cap for tickers in the [@Pharmaceuticals: Major] industry ranges from $979.64B to $0. The average market capitalization across the [@Pharmaceuticals: Major] industry is $179.55B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

PFE’s FA Score shows that 1 FA rating(s) are green whileSNY’s FA Score has 1 green FA rating(s).

  • PFE’s FA Score: 1 green, 4 red.
  • SNY’s FA Score: 1 green, 4 red.
According to our system of comparison, both PFE and SNY are a bad buy in the long-term.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

PFE’s TA Score shows that 2 TA indicator(s) are bullish while SNY’s TA Score has 2 bullish TA indicator(s).

  • PFE’s TA Score: 2 bullish, 6 bearish.
  • SNY’s TA Score: 2 bullish, 8 bearish.
According to our system of comparison, PFE is a better buy in the short-term than SNY.

Price Growth

PFE (@Pharmaceuticals: Major) experienced а -3.67% price change this week, while SNY (@Pharmaceuticals: Major) price change was -3.92% for the same time period.

The average weekly price growth across all stocks in the @Pharmaceuticals: Major industry was +1.18%. For the same industry, the average monthly price growth was +8.31%, and the average quarterly price growth was +2.32%.

Reported Earning Dates

PFE is expected to report earnings on Aug 04, 2026.

SNY is expected to report earnings on Jul 30, 2026.

Industries' Descriptions

@Pharmaceuticals: Major (+1.18% weekly)

The Major Pharmaceuticals industry includes companies that are involved in various processes of creating drugs to treat/prevent diseases. These companies engage in research, testing and manufacturing, as well as the distribution of pharmaceuticals into markets. Johnson & Johnson, Merck & Co., Inc., Pfizer Inc. and Novartis are among the largest companies in this category.

SUMMARIES
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FUNDAMENTALS
Fundamentals
PFE($144B) has a higher market cap than SNY($101B). PFE (19.24) and SNY (18.43) have similar P/E ratio . PFE YTD gains are higher at: 4.640 vs. SNY (-7.701). PFE has higher annual earnings (EBITDA): 17.2B vs. SNY (8.52B). PFE has more cash in the bank: 13.1B vs. SNY (5.54B). SNY has less debt than PFE: SNY (20B) vs PFE (63.7B). PFE has higher revenues than SNY: PFE (63.3B) vs SNY (47.4B).
PFESNYPFE / SNY
Capitalization144B101B143%
EBITDA17.2B8.52B202%
Gain YTD4.640-7.701-60%
P/E Ratio19.2418.43104%
Revenue63.3B47.4B134%
Total Cash13.1B5.54B236%
Total Debt63.7B20B319%
FUNDAMENTALS RATINGS
PFE vs SNY: Fundamental Ratings
PFE
SNY
OUTLOOK RATING
1..100
1358
VALUATION
overvalued / fair valued / undervalued
1..100
5
Undervalued
3
Undervalued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
7871
PRICE GROWTH RATING
1..100
5660
P/E GROWTH RATING
1..100
4141
SEASONALITY SCORE
1..100
n/a50

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

SNY's Valuation (3) in the Pharmaceuticals Major industry is in the same range as PFE (5). This means that SNY’s stock grew similarly to PFE’s over the last 12 months.

SNY's Profit vs Risk Rating (100) in the Pharmaceuticals Major industry is in the same range as PFE (100). This means that SNY’s stock grew similarly to PFE’s over the last 12 months.

SNY's SMR Rating (71) in the Pharmaceuticals Major industry is in the same range as PFE (78). This means that SNY’s stock grew similarly to PFE’s over the last 12 months.

PFE's Price Growth Rating (56) in the Pharmaceuticals Major industry is in the same range as SNY (60). This means that PFE’s stock grew similarly to SNY’s over the last 12 months.

PFE's P/E Growth Rating (41) in the Pharmaceuticals Major industry is in the same range as SNY (41). This means that PFE’s stock grew similarly to SNY’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
PFESNY
RSI
ODDS (%)
N/A
Bearish Trend 20 days ago
55%
Stochastic
ODDS (%)
Bearish Trend 3 days ago
57%
Bullish Trend 3 days ago
54%
Momentum
ODDS (%)
Bearish Trend 3 days ago
52%
Bearish Trend 3 days ago
47%
MACD
ODDS (%)
Bearish Trend 3 days ago
67%
Bearish Trend 3 days ago
47%
TrendWeek
ODDS (%)
Bearish Trend 3 days ago
58%
Bearish Trend 3 days ago
50%
TrendMonth
ODDS (%)
Bearish Trend 3 days ago
54%
Bearish Trend 3 days ago
43%
Advances
ODDS (%)
Bullish Trend 9 days ago
56%
Bullish Trend 9 days ago
50%
Declines
ODDS (%)
Bearish Trend 3 days ago
58%
Bearish Trend 3 days ago
49%
BollingerBands
ODDS (%)
Bullish Trend 5 days ago
59%
Bearish Trend 3 days ago
56%
Aroon
ODDS (%)
Bearish Trend 3 days ago
58%
Bearish Trend 3 days ago
55%
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PFE
Daily Signal:
Gain/Loss:
SNY
Daily Signal:
Gain/Loss:
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PFE and

Correlation & Price change

A.I.dvisor indicates that over the last year, PFE has been loosely correlated with BMY. These tickers have moved in lockstep 59% of the time. This A.I.-generated data suggests there is some statistical probability that if PFE jumps, then BMY could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To PFE
1D Price
Change %
PFE100%
-2.74%
BMY - PFE
59%
Loosely correlated
-2.32%
MRK - PFE
55%
Loosely correlated
-1.36%
AMGN - PFE
53%
Loosely correlated
-1.19%
NVS - PFE
53%
Loosely correlated
-2.52%
BIIB - PFE
51%
Loosely correlated
-1.05%
More

SNY and

Correlation & Price change

A.I.dvisor indicates that over the last year, SNY has been loosely correlated with NVS. These tickers have moved in lockstep 49% of the time. This A.I.-generated data suggests there is some statistical probability that if SNY jumps, then NVS could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SNY
1D Price
Change %
SNY100%
-0.28%
NVS - SNY
49%
Loosely correlated
-2.52%
BMY - SNY
47%
Loosely correlated
-2.32%
PFE - SNY
44%
Loosely correlated
-2.74%
MRK - SNY
44%
Loosely correlated
-1.36%
GSK - SNY
41%
Loosely correlated
-2.84%
More