AGIO
Price
$40.50
Change
+$0.57 (+1.43%)
Updated
Oct 3 closing price
Capitalization
2.35B
24 days until earnings call
ZYME
Price
$17.18
Change
+$0.24 (+1.42%)
Updated
Oct 6, 10:55 AM (EDT)
Capitalization
1.28B
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AGIO vs ZYME

Header iconAGIO vs ZYME Comparison
Open Charts AGIO vs ZYMEBanner chart's image
Agios Pharmaceuticals
Price$40.50
Change+$0.57 (+1.43%)
Volume$525.44K
Capitalization2.35B
Zymeworks
Price$17.18
Change+$0.24 (+1.42%)
Volume$1K
Capitalization1.28B
AGIO vs ZYME Comparison Chart in %
AGIO
Daily Signalchanged days ago
Gain/Loss if bought
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ZYME
Daily Signalchanged days ago
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AGIO vs. ZYME commentary
Oct 06, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is AGIO is a StrongBuy and ZYME is a Hold.

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COMPARISON
Comparison
Oct 06, 2025
Stock price -- (AGIO: $40.50 vs. ZYME: $16.94)
Brand notoriety: AGIO and ZYME are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: AGIO: 63% vs. ZYME: 105%
Market capitalization -- AGIO: $2.35B vs. ZYME: $1.28B
AGIO [@Biotechnology] is valued at $2.35B. ZYME’s [@Biotechnology] market capitalization is $1.28B. The market cap for tickers in the [@Biotechnology] industry ranges from $103.4B to $0. The average market capitalization across the [@Biotechnology] industry is $2.05B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

AGIO’s FA Score shows that 1 FA rating(s) are green whileZYME’s FA Score has 0 green FA rating(s).

  • AGIO’s FA Score: 1 green, 4 red.
  • ZYME’s FA Score: 0 green, 5 red.
According to our system of comparison, AGIO is a better buy in the long-term than ZYME.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

AGIO’s TA Score shows that 6 TA indicator(s) are bullish while ZYME’s TA Score has 4 bullish TA indicator(s).

  • AGIO’s TA Score: 6 bullish, 3 bearish.
  • ZYME’s TA Score: 4 bullish, 4 bearish.
According to our system of comparison, AGIO is a better buy in the short-term than ZYME.

Price Growth

AGIO (@Biotechnology) experienced а +4.03% price change this week, while ZYME (@Biotechnology) price change was +2.05% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +4.93%. For the same industry, the average monthly price growth was +13.10%, and the average quarterly price growth was +80.18%.

Reported Earning Dates

AGIO is expected to report earnings on Oct 30, 2025.

Industries' Descriptions

@Biotechnology (+4.93% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
AGIO($2.35B) has a higher market cap than ZYME($1.28B). AGIO YTD gains are higher at: 23.250 vs. ZYME (15.710). ZYME has higher annual earnings (EBITDA): -69.77M vs. AGIO (-456.28M). AGIO has more cash in the bank: 939M vs. ZYME (281M). ZYME has less debt than AGIO: ZYME (18.7M) vs AGIO (48.8M). ZYME has higher revenues than AGIO: ZYME (123M) vs AGIO (40.9M).
AGIOZYMEAGIO / ZYME
Capitalization2.35B1.28B183%
EBITDA-456.28M-69.77M654%
Gain YTD23.25015.710148%
P/E Ratio3.54N/A-
Revenue40.9M123M33%
Total Cash939M281M334%
Total Debt48.8M18.7M261%
FUNDAMENTALS RATINGS
AGIO vs ZYME: Fundamental Ratings
AGIO
ZYME
OUTLOOK RATING
1..100
872
VALUATION
overvalued / fair valued / undervalued
1..100
43
Fair valued
47
Fair valued
PROFIT vs RISK RATING
1..100
96100
SMR RATING
1..100
1795
PRICE GROWTH RATING
1..100
4740
P/E GROWTH RATING
1..100
5962
SEASONALITY SCORE
1..100
7544

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

AGIO's Valuation (43) in the Biotechnology industry is in the same range as ZYME (47) in the Pharmaceuticals Major industry. This means that AGIO’s stock grew similarly to ZYME’s over the last 12 months.

AGIO's Profit vs Risk Rating (96) in the Biotechnology industry is in the same range as ZYME (100) in the Pharmaceuticals Major industry. This means that AGIO’s stock grew similarly to ZYME’s over the last 12 months.

AGIO's SMR Rating (17) in the Biotechnology industry is significantly better than the same rating for ZYME (95) in the Pharmaceuticals Major industry. This means that AGIO’s stock grew significantly faster than ZYME’s over the last 12 months.

ZYME's Price Growth Rating (40) in the Pharmaceuticals Major industry is in the same range as AGIO (47) in the Biotechnology industry. This means that ZYME’s stock grew similarly to AGIO’s over the last 12 months.

AGIO's P/E Growth Rating (59) in the Biotechnology industry is in the same range as ZYME (62) in the Pharmaceuticals Major industry. This means that AGIO’s stock grew similarly to ZYME’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
AGIOZYME
RSI
ODDS (%)
N/A
Bearish Trend 4 days ago
86%
Stochastic
ODDS (%)
Bearish Trend 4 days ago
77%
Bearish Trend 4 days ago
82%
Momentum
ODDS (%)
Bullish Trend 4 days ago
76%
Bullish Trend 4 days ago
79%
MACD
ODDS (%)
Bullish Trend 4 days ago
77%
Bullish Trend 4 days ago
71%
TrendWeek
ODDS (%)
Bullish Trend 4 days ago
79%
Bullish Trend 4 days ago
80%
TrendMonth
ODDS (%)
Bearish Trend 4 days ago
76%
Bullish Trend 4 days ago
82%
Advances
ODDS (%)
Bullish Trend 7 days ago
78%
Bullish Trend 8 days ago
82%
Declines
ODDS (%)
Bearish Trend 5 days ago
75%
Bearish Trend 5 days ago
83%
BollingerBands
ODDS (%)
Bearish Trend 4 days ago
69%
Bearish Trend 4 days ago
81%
Aroon
ODDS (%)
Bullish Trend 4 days ago
77%
Bullish Trend 4 days ago
85%
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AGIO
Daily Signalchanged days ago
Gain/Loss if bought
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ZYME
Daily Signalchanged days ago
Gain/Loss if bought
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AGIO and

Correlation & Price change

A.I.dvisor indicates that over the last year, AGIO has been loosely correlated with LGND. These tickers have moved in lockstep 50% of the time. This A.I.-generated data suggests there is some statistical probability that if AGIO jumps, then LGND could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To AGIO
1D Price
Change %
AGIO100%
+1.43%
LGND - AGIO
50%
Loosely correlated
+0.48%
VRDN - AGIO
46%
Loosely correlated
+2.03%
CRNX - AGIO
46%
Loosely correlated
-1.57%
AXON - AGIO
45%
Loosely correlated
-0.70%
ZYME - AGIO
45%
Loosely correlated
+0.24%
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