ALNY
Price
$451.20
Change
+$7.56 (+1.70%)
Updated
Aug 26 closing price
Capitalization
59.14B
57 days until earnings call
IONS
Price
$42.17
Change
+$0.35 (+0.84%)
Updated
Aug 26 closing price
Capitalization
6.72B
64 days until earnings call
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ALNY vs IONS

Header iconALNY vs IONS Comparison
Open Charts ALNY vs IONSBanner chart's image
Alnylam Pharmaceuticals
Price$451.20
Change+$7.56 (+1.70%)
Volume$1.18M
Capitalization59.14B
Ionis Pharmaceuticals
Price$42.17
Change+$0.35 (+0.84%)
Volume$2.6M
Capitalization6.72B
ALNY vs IONS Comparison Chart in %
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ALNY
Daily Signalchanged days ago
Gain/Loss if bought
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IONS
Daily Signalchanged days ago
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ALNY vs. IONS commentary
Aug 27, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is ALNY is a StrongBuy and IONS is a Buy.

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COMPARISON
Comparison
Aug 27, 2025
Stock price -- (ALNY: $451.20 vs. IONS: $42.17)
Brand notoriety: ALNY and IONS are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: ALNY: 107% vs. IONS: 128%
Market capitalization -- ALNY: $59.14B vs. IONS: $6.72B
ALNY [@Biotechnology] is valued at $59.14B. IONS’s [@Biotechnology] market capitalization is $6.72B. The market cap for tickers in the [@Biotechnology] industry ranges from $99.27B to $0. The average market capitalization across the [@Biotechnology] industry is $1.85B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

ALNY’s FA Score shows that 1 FA rating(s) are green whileIONS’s FA Score has 0 green FA rating(s).

  • ALNY’s FA Score: 1 green, 4 red.
  • IONS’s FA Score: 0 green, 5 red.
According to our system of comparison, ALNY is a better buy in the long-term than IONS.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

ALNY’s TA Score shows that 3 TA indicator(s) are bullish while IONS’s TA Score has 3 bullish TA indicator(s).

  • ALNY’s TA Score: 3 bullish, 5 bearish.
  • IONS’s TA Score: 3 bullish, 4 bearish.
According to our system of comparison, IONS is a better buy in the short-term than ALNY.

Price Growth

ALNY (@Biotechnology) experienced а -1.54% price change this week, while IONS (@Biotechnology) price change was -0.73% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +4.28%. For the same industry, the average monthly price growth was +23.07%, and the average quarterly price growth was +32.06%.

Reported Earning Dates

ALNY is expected to report earnings on Oct 23, 2025.

IONS is expected to report earnings on Oct 30, 2025.

Industries' Descriptions

@Biotechnology (+4.28% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
ALNY($59.1B) has a higher market cap than IONS($6.72B). ALNY YTD gains are higher at: 91.747 vs. IONS (20.624). IONS (-170.69M) and ALNY (-170.84M) have comparable annual earnings (EBITDA) . ALNY has more cash in the bank: 2.86B vs. IONS (2.29B). ALNY has less debt than IONS: ALNY (1.3B) vs IONS (1.42B). ALNY has higher revenues than IONS: ALNY (2.46B) vs IONS (944M).
ALNYIONSALNY / IONS
Capitalization59.1B6.72B879%
EBITDA-170.84M-170.69M100%
Gain YTD91.74720.624445%
P/E RatioN/AN/A-
Revenue2.46B944M261%
Total Cash2.86B2.29B125%
Total Debt1.3B1.42B91%
FUNDAMENTALS RATINGS
ALNY vs IONS: Fundamental Ratings
ALNY
IONS
OUTLOOK RATING
1..100
2777
VALUATION
overvalued / fair valued / undervalued
1..100
97
Overvalued
96
Overvalued
PROFIT vs RISK RATING
1..100
10100
SMR RATING
1..100
10097
PRICE GROWTH RATING
1..100
3646
P/E GROWTH RATING
1..100
10066
SEASONALITY SCORE
1..100
5050

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

IONS's Valuation (96) in the Biotechnology industry is in the same range as ALNY (97). This means that IONS’s stock grew similarly to ALNY’s over the last 12 months.

ALNY's Profit vs Risk Rating (10) in the Biotechnology industry is significantly better than the same rating for IONS (100). This means that ALNY’s stock grew significantly faster than IONS’s over the last 12 months.

IONS's SMR Rating (97) in the Biotechnology industry is in the same range as ALNY (100). This means that IONS’s stock grew similarly to ALNY’s over the last 12 months.

ALNY's Price Growth Rating (36) in the Biotechnology industry is in the same range as IONS (46). This means that ALNY’s stock grew similarly to IONS’s over the last 12 months.

IONS's P/E Growth Rating (66) in the Biotechnology industry is somewhat better than the same rating for ALNY (100). This means that IONS’s stock grew somewhat faster than ALNY’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
ALNYIONS
RSI
ODDS (%)
Bearish Trend 2 days ago
71%
N/A
Stochastic
ODDS (%)
Bearish Trend 2 days ago
68%
Bearish Trend 2 days ago
73%
Momentum
ODDS (%)
Bullish Trend 6 days ago
79%
Bullish Trend 2 days ago
69%
MACD
ODDS (%)
Bearish Trend 2 days ago
69%
Bearish Trend 2 days ago
70%
TrendWeek
ODDS (%)
Bearish Trend 2 days ago
64%
Bearish Trend 2 days ago
68%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
73%
Bearish Trend 2 days ago
69%
Advances
ODDS (%)
Bullish Trend 6 days ago
76%
Bullish Trend 6 days ago
64%
Declines
ODDS (%)
Bearish Trend 2 days ago
64%
Bearish Trend 2 days ago
68%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
64%
Bearish Trend 2 days ago
72%
Aroon
ODDS (%)
Bullish Trend 2 days ago
78%
Bullish Trend 2 days ago
69%
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ALNY
Daily Signalchanged days ago
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IONS
Daily Signalchanged days ago
Gain/Loss if bought
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ALNY and

Correlation & Price change

A.I.dvisor indicates that over the last year, ALNY has been loosely correlated with IONS. These tickers have moved in lockstep 56% of the time. This A.I.-generated data suggests there is some statistical probability that if ALNY jumps, then IONS could also see price increases.

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1W
1M
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6M
1Y
5Y
Ticker /
NAME
Correlation
To ALNY
1D Price
Change %
ALNY100%
+1.70%
IONS - ALNY
56%
Loosely correlated
+0.84%
SGMO - ALNY
42%
Loosely correlated
-1.82%
ARGX - ALNY
39%
Loosely correlated
+4.54%
INSM - ALNY
38%
Loosely correlated
+3.00%
AXSM - ALNY
38%
Loosely correlated
+4.16%
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