ANNX
Price
$2.54
Change
+$0.09 (+3.67%)
Updated
Aug 4, 04:59 PM (EDT)
Capitalization
277.58M
14 days until earnings call
SYRE
Price
$16.18
Change
-$0.08 (-0.49%)
Updated
Aug 4, 04:59 PM (EDT)
Capitalization
975.31M
Earnings call today
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ANNX vs SYRE

Header iconANNX vs SYRE Comparison
Open Charts ANNX vs SYREBanner chart's image
Annexon
Price$2.54
Change+$0.09 (+3.67%)
Volume$7.37K
Capitalization277.58M
Spyre Therapeutics
Price$16.18
Change-$0.08 (-0.49%)
Volume$21.5K
Capitalization975.31M
ANNX vs SYRE Comparison Chart in %
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ANNX
Daily Signalchanged days ago
Gain/Loss if bought
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SYRE
Daily Signalchanged days ago
Gain/Loss if bought
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ANNX vs. SYRE commentary
Aug 05, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is ANNX is a Hold and SYRE is a Hold.

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COMPARISON
Comparison
Aug 05, 2025
Stock price -- (ANNX: $2.45 vs. SYRE: $16.26)
Brand notoriety: ANNX and SYRE are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: ANNX: 62% vs. SYRE: 93%
Market capitalization -- ANNX: $268.8M vs. SYRE: $981.35M
ANNX [@Biotechnology] is valued at $268.8M. SYRE’s [@Biotechnology] market capitalization is $981.35M. The market cap for tickers in the [@Biotechnology] industry ranges from $213.98B to $0. The average market capitalization across the [@Biotechnology] industry is $2.32B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

ANNX’s FA Score shows that 1 FA rating(s) are green whileSYRE’s FA Score has 0 green FA rating(s).

  • ANNX’s FA Score: 1 green, 4 red.
  • SYRE’s FA Score: 0 green, 5 red.
According to our system of comparison, ANNX is a better buy in the long-term than SYRE.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

ANNX’s TA Score shows that 5 TA indicator(s) are bullish while SYRE’s TA Score has 3 bullish TA indicator(s).

  • ANNX’s TA Score: 5 bullish, 4 bearish.
  • SYRE’s TA Score: 3 bullish, 5 bearish.
According to our system of comparison, ANNX is a better buy in the short-term than SYRE.

Price Growth

ANNX (@Biotechnology) experienced а -2.39% price change this week, while SYRE (@Biotechnology) price change was -8.60% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was -2.87%. For the same industry, the average monthly price growth was +14.71%, and the average quarterly price growth was +10.87%.

Reported Earning Dates

ANNX is expected to report earnings on Nov 12, 2025.

SYRE is expected to report earnings on Nov 06, 2025.

Industries' Descriptions

@Biotechnology (-2.87% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
SYRE($975M) has a higher market cap than ANNX($278M). SYRE YTD gains are higher at: -30.155 vs. ANNX (-52.242). ANNX has higher annual earnings (EBITDA): -180.76M vs. SYRE (-214.36M). SYRE has more cash in the bank: 565M vs. ANNX (264M). SYRE has less debt than ANNX: SYRE (0) vs ANNX (28.3M). ANNX (0) and SYRE (0) have equivalent revenues.
ANNXSYREANNX / SYRE
Capitalization278M975M29%
EBITDA-180.76M-214.36M84%
Gain YTD-52.242-30.155173%
P/E RatioN/A1.72-
Revenue00-
Total Cash264M565M47%
Total Debt28.3M0-
FUNDAMENTALS RATINGS
SYRE: Fundamental Ratings
SYRE
OUTLOOK RATING
1..100
50
VALUATION
overvalued / fair valued / undervalued
1..100
74
Overvalued
PROFIT vs RISK RATING
1..100
100
SMR RATING
1..100
98
PRICE GROWTH RATING
1..100
62
P/E GROWTH RATING
1..100
80
SEASONALITY SCORE
1..100
19

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

TECHNICAL ANALYSIS
Technical Analysis
ANNXSYRE
RSI
ODDS (%)
Bearish Trend 4 days ago
90%
N/A
Stochastic
ODDS (%)
Bullish Trend 4 days ago
83%
Bearish Trend 4 days ago
86%
Momentum
ODDS (%)
Bullish Trend 4 days ago
81%
Bearish Trend 4 days ago
84%
MACD
ODDS (%)
Bearish Trend 4 days ago
83%
Bearish Trend 4 days ago
80%
TrendWeek
ODDS (%)
Bearish Trend 4 days ago
87%
Bearish Trend 4 days ago
87%
TrendMonth
ODDS (%)
Bearish Trend 4 days ago
86%
Bullish Trend 4 days ago
84%
Advances
ODDS (%)
Bullish Trend 12 days ago
84%
Bullish Trend 13 days ago
85%
Declines
ODDS (%)
Bearish Trend 7 days ago
89%
Bearish Trend 4 days ago
90%
BollingerBands
ODDS (%)
Bearish Trend 4 days ago
90%
Bearish Trend 4 days ago
90%
Aroon
ODDS (%)
Bullish Trend 4 days ago
79%
Bullish Trend 4 days ago
81%
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ANNX
Daily Signalchanged days ago
Gain/Loss if bought
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SYRE
Daily Signalchanged days ago
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ANNX and

Correlation & Price change

A.I.dvisor indicates that over the last year, ANNX has been loosely correlated with IDYA. These tickers have moved in lockstep 50% of the time. This A.I.-generated data suggests there is some statistical probability that if ANNX jumps, then IDYA could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To ANNX
1D Price
Change %
ANNX100%
+2.08%
IDYA - ANNX
50%
Loosely correlated
-0.33%
OCUL - ANNX
47%
Loosely correlated
+2.94%
ZYME - ANNX
45%
Loosely correlated
+0.08%
NRIX - ANNX
45%
Loosely correlated
-1.95%
SYRE - ANNX
44%
Loosely correlated
-4.18%
More

SYRE and

Correlation & Price change

A.I.dvisor indicates that over the last year, SYRE has been loosely correlated with IDYA. These tickers have moved in lockstep 60% of the time. This A.I.-generated data suggests there is some statistical probability that if SYRE jumps, then IDYA could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SYRE
1D Price
Change %
SYRE100%
-4.18%
IDYA - SYRE
60%
Loosely correlated
-0.33%
CGON - SYRE
58%
Loosely correlated
-1.42%
BEAM - SYRE
58%
Loosely correlated
-4.46%
XNCR - SYRE
57%
Loosely correlated
-4.09%
IMNM - SYRE
55%
Loosely correlated
+0.67%
More