APGE
Price
$38.22
Change
+$0.70 (+1.87%)
Updated
Sep 26 closing price
Capitalization
2.28B
50 days until earnings call
SYRE
Price
$16.24
Change
+$0.63 (+4.04%)
Updated
Sep 26 closing price
Capitalization
980.91M
38 days until earnings call
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APGE vs SYRE

Header iconAPGE vs SYRE Comparison
Open Charts APGE vs SYREBanner chart's image
Apogee Therapeutics
Price$38.22
Change+$0.70 (+1.87%)
Volume$649.02K
Capitalization2.28B
Spyre Therapeutics
Price$16.24
Change+$0.63 (+4.04%)
Volume$985.41K
Capitalization980.91M
APGE vs SYRE Comparison Chart in %
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APGE
Daily Signalchanged days ago
Gain/Loss if bought
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SYRE
Daily Signalchanged days ago
Gain/Loss if bought
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APGE vs. SYRE commentary
Sep 29, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is APGE is a Buy and SYRE is a Buy.

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COMPARISON
Comparison
Sep 29, 2025
Stock price -- (APGE: $38.22 vs. SYRE: $16.24)
Brand notoriety: APGE and SYRE are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: APGE: 122% vs. SYRE: 177%
Market capitalization -- APGE: $2.28B vs. SYRE: $980.91M
APGE [@Biotechnology] is valued at $2.28B. SYRE’s [@Biotechnology] market capitalization is $980.91M. The market cap for tickers in the [@Biotechnology] industry ranges from $98.9B to $0. The average market capitalization across the [@Biotechnology] industry is $1.9B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

APGE’s FA Score shows that 0 FA rating(s) are green whileSYRE’s FA Score has 0 green FA rating(s).

  • APGE’s FA Score: 0 green, 5 red.
  • SYRE’s FA Score: 0 green, 5 red.
According to our system of comparison, APGE is a better buy in the long-term than SYRE.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

APGE’s TA Score shows that 5 TA indicator(s) are bullish while SYRE’s TA Score has 6 bullish TA indicator(s).

  • APGE’s TA Score: 5 bullish, 2 bearish.
  • SYRE’s TA Score: 6 bullish, 4 bearish.
According to our system of comparison, APGE is a better buy in the short-term than SYRE.

Price Growth

APGE (@Biotechnology) experienced а +4.63% price change this week, while SYRE (@Biotechnology) price change was +9.14% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +3.96%. For the same industry, the average monthly price growth was +9.24%, and the average quarterly price growth was +51.43%.

Reported Earning Dates

APGE is expected to report earnings on Nov 18, 2025.

SYRE is expected to report earnings on Nov 06, 2025.

Industries' Descriptions

@Biotechnology (+3.96% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
APGE($2.28B) has a higher market cap than SYRE($981M). APGE YTD gains are higher at: -15.629 vs. SYRE (-30.241). SYRE has higher annual earnings (EBITDA): -222.15M vs. APGE (-270.1M). SYRE (527M) and APGE (505M) have equal amount of cash in the bank . SYRE has less debt than APGE: SYRE (0) vs APGE (10.8M). APGE (0) and SYRE (0) have equivalent revenues.
APGESYREAPGE / SYRE
Capitalization2.28B981M232%
EBITDA-270.1M-222.15M122%
Gain YTD-15.629-30.24152%
P/E RatioN/A1.72-
Revenue00-
Total Cash505M527M96%
Total Debt10.8M0-
FUNDAMENTALS RATINGS
SYRE: Fundamental Ratings
SYRE
OUTLOOK RATING
1..100
21
VALUATION
overvalued / fair valued / undervalued
1..100
71
Overvalued
PROFIT vs RISK RATING
1..100
100
SMR RATING
1..100
98
PRICE GROWTH RATING
1..100
63
P/E GROWTH RATING
1..100
79
SEASONALITY SCORE
1..100
43

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

TECHNICAL ANALYSIS
Technical Analysis
APGESYRE
RSI
ODDS (%)
N/A
Bullish Trend 4 days ago
89%
Stochastic
ODDS (%)
Bearish Trend 4 days ago
84%
Bullish Trend 4 days ago
84%
Momentum
ODDS (%)
Bullish Trend 4 days ago
77%
Bullish Trend 4 days ago
84%
MACD
ODDS (%)
Bullish Trend 4 days ago
78%
Bullish Trend 4 days ago
87%
TrendWeek
ODDS (%)
Bullish Trend 4 days ago
83%
Bullish Trend 4 days ago
83%
TrendMonth
ODDS (%)
Bullish Trend 4 days ago
81%
Bearish Trend 4 days ago
89%
Advances
ODDS (%)
Bullish Trend 6 days ago
83%
Bullish Trend 6 days ago
84%
Declines
ODDS (%)
Bearish Trend 14 days ago
75%
Bearish Trend 14 days ago
90%
BollingerBands
ODDS (%)
N/A
Bullish Trend 4 days ago
83%
Aroon
ODDS (%)
Bullish Trend 4 days ago
84%
Bearish Trend 4 days ago
89%
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APGE
Daily Signalchanged days ago
Gain/Loss if bought
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SYRE
Daily Signalchanged days ago
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APGE and

Correlation & Price change

A.I.dvisor indicates that over the last year, APGE has been loosely correlated with SYRE. These tickers have moved in lockstep 55% of the time. This A.I.-generated data suggests there is some statistical probability that if APGE jumps, then SYRE could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To APGE
1D Price
Change %
APGE100%
+1.87%
SYRE - APGE
55%
Loosely correlated
+4.04%
DYN - APGE
50%
Loosely correlated
+4.53%
NUVL - APGE
50%
Loosely correlated
+4.99%
CRNX - APGE
49%
Loosely correlated
+27.92%
CGON - APGE
49%
Loosely correlated
+2.91%
More

SYRE and

Correlation & Price change

A.I.dvisor indicates that over the last year, SYRE has been loosely correlated with IDYA. These tickers have moved in lockstep 59% of the time. This A.I.-generated data suggests there is some statistical probability that if SYRE jumps, then IDYA could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SYRE
1D Price
Change %
SYRE100%
+4.04%
IDYA - SYRE
59%
Loosely correlated
+4.44%
CGON - SYRE
59%
Loosely correlated
+2.91%
XNCR - SYRE
57%
Loosely correlated
+12.00%
CRNX - SYRE
56%
Loosely correlated
+27.92%
BEAM - SYRE
55%
Loosely correlated
-0.52%
More