APLS
Price
$25.73
Change
+$0.81 (+3.25%)
Updated
Oct 9, 04:59 PM (EDT)
Capitalization
3.25B
31 days until earnings call
DNLI
Price
$16.15
Change
+$0.50 (+3.19%)
Updated
Oct 9, 04:59 PM (EDT)
Capitalization
2.29B
20 days until earnings call
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APLS vs DNLI

Header iconAPLS vs DNLI Comparison
Open Charts APLS vs DNLIBanner chart's image
Apellis Pharmaceuticals
Price$25.73
Change+$0.81 (+3.25%)
Volume$76.13K
Capitalization3.25B
Denali Therapeutics
Price$16.15
Change+$0.50 (+3.19%)
Volume$30.15K
Capitalization2.29B
APLS vs DNLI Comparison Chart in %
APLS
Daily Signalchanged days ago
Gain/Loss if bought
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DNLI
Daily Signalchanged days ago
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APLS vs. DNLI commentary
Oct 10, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is APLS is a StrongBuy and DNLI is a Buy.

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COMPARISON
Comparison
Oct 10, 2025
Stock price -- (APLS: $25.73 vs. DNLI: $16.17)
Brand notoriety: APLS and DNLI are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: APLS: 141% vs. DNLI: 78%
Market capitalization -- APLS: $3.25B vs. DNLI: $2.29B
APLS [@Biotechnology] is valued at $3.25B. DNLI’s [@Biotechnology] market capitalization is $2.29B. The market cap for tickers in the [@Biotechnology] industry ranges from $107.98B to $0. The average market capitalization across the [@Biotechnology] industry is $2.04B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

APLS’s FA Score shows that 0 FA rating(s) are green whileDNLI’s FA Score has 0 green FA rating(s).

  • APLS’s FA Score: 0 green, 5 red.
  • DNLI’s FA Score: 0 green, 5 red.
According to our system of comparison, APLS is a better buy in the long-term than DNLI.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

APLS’s TA Score shows that 6 TA indicator(s) are bullish while DNLI’s TA Score has 5 bullish TA indicator(s).

  • APLS’s TA Score: 6 bullish, 5 bearish.
  • DNLI’s TA Score: 5 bullish, 5 bearish.
According to our system of comparison, APLS is a better buy in the short-term than DNLI.

Price Growth

APLS (@Biotechnology) experienced а +11.34% price change this week, while DNLI (@Biotechnology) price change was +6.38% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +8.88%. For the same industry, the average monthly price growth was +22.21%, and the average quarterly price growth was +89.30%.

Reported Earning Dates

APLS is expected to report earnings on Nov 10, 2025.

DNLI is expected to report earnings on Oct 30, 2025.

Industries' Descriptions

@Biotechnology (+8.88% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
APLS($3.25B) has a higher market cap than DNLI($2.29B). APLS YTD gains are higher at: -19.367 vs. DNLI (-20.658). APLS has higher annual earnings (EBITDA): -178.43M vs. DNLI (-521.52M). DNLI has more cash in the bank: 899M vs. APLS (370M). DNLI has less debt than APLS: DNLI (46.6M) vs APLS (470M). APLS has higher revenues than DNLI: APLS (755M) vs DNLI (0).
APLSDNLIAPLS / DNLI
Capitalization3.25B2.29B142%
EBITDA-178.43M-521.52M34%
Gain YTD-19.367-20.65894%
P/E RatioN/AN/A-
Revenue755M0-
Total Cash370M899M41%
Total Debt470M46.6M1,009%
FUNDAMENTALS RATINGS
APLS vs DNLI: Fundamental Ratings
APLS
DNLI
OUTLOOK RATING
1..100
615
VALUATION
overvalued / fair valued / undervalued
1..100
64
Fair valued
93
Overvalued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
9997
PRICE GROWTH RATING
1..100
5058
P/E GROWTH RATING
1..100
100100
SEASONALITY SCORE
1..100
8550

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

APLS's Valuation (64) in the Medical Distributors industry is in the same range as DNLI (93) in the Biotechnology industry. This means that APLS’s stock grew similarly to DNLI’s over the last 12 months.

APLS's Profit vs Risk Rating (100) in the Medical Distributors industry is in the same range as DNLI (100) in the Biotechnology industry. This means that APLS’s stock grew similarly to DNLI’s over the last 12 months.

DNLI's SMR Rating (97) in the Biotechnology industry is in the same range as APLS (99) in the Medical Distributors industry. This means that DNLI’s stock grew similarly to APLS’s over the last 12 months.

APLS's Price Growth Rating (50) in the Medical Distributors industry is in the same range as DNLI (58) in the Biotechnology industry. This means that APLS’s stock grew similarly to DNLI’s over the last 12 months.

APLS's P/E Growth Rating (100) in the Medical Distributors industry is in the same range as DNLI (100) in the Biotechnology industry. This means that APLS’s stock grew similarly to DNLI’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
APLSDNLI
RSI
ODDS (%)
Bullish Trend 2 days ago
81%
Bearish Trend 1 day ago
90%
Stochastic
ODDS (%)
Bearish Trend 2 days ago
88%
Bearish Trend 1 day ago
84%
Momentum
ODDS (%)
Bullish Trend 2 days ago
76%
Bullish Trend 1 day ago
80%
MACD
ODDS (%)
Bullish Trend 2 days ago
75%
Bullish Trend 1 day ago
82%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
79%
Bullish Trend 1 day ago
77%
TrendMonth
ODDS (%)
Bearish Trend 2 days ago
85%
Bullish Trend 1 day ago
72%
Advances
ODDS (%)
Bullish Trend 3 days ago
81%
Bullish Trend 1 day ago
76%
Declines
ODDS (%)
Bearish Trend 15 days ago
79%
Bearish Trend 3 days ago
81%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 1 day ago
86%
Aroon
ODDS (%)
Bearish Trend 2 days ago
86%
Bearish Trend 1 day ago
84%
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APLS
Daily Signalchanged days ago
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DNLI
Daily Signalchanged days ago
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