APLS
Price
$23.15
Change
-$0.99 (-4.10%)
Updated
Oct 14 closing price
Capitalization
2.92B
26 days until earnings call
KRYS
Price
$188.05
Change
+$3.31 (+1.79%)
Updated
Oct 14 closing price
Capitalization
5.44B
26 days until earnings call
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APLS vs KRYS

Header iconAPLS vs KRYS Comparison
Open Charts APLS vs KRYSBanner chart's image
Apellis Pharmaceuticals
Price$23.15
Change-$0.99 (-4.10%)
Volume$1.46M
Capitalization2.92B
Krystal Biotech
Price$188.05
Change+$3.31 (+1.79%)
Volume$224.36K
Capitalization5.44B
APLS vs KRYS Comparison Chart in %
APLS
Daily Signalchanged days ago
Gain/Loss if bought
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KRYS
Daily Signalchanged days ago
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APLS vs. KRYS commentary
Oct 15, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is APLS is a Hold and KRYS is a Hold.

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COMPARISON
Comparison
Oct 15, 2025
Stock price -- (APLS: $23.15 vs. KRYS: $188.05)
Brand notoriety: APLS and KRYS are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: APLS: 67% vs. KRYS: 67%
Market capitalization -- APLS: $2.92B vs. KRYS: $5.44B
APLS [@Biotechnology] is valued at $2.92B. KRYS’s [@Biotechnology] market capitalization is $5.44B. The market cap for tickers in the [@Biotechnology] industry ranges from $105.69B to $0. The average market capitalization across the [@Biotechnology] industry is $2.02B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

APLS’s FA Score shows that 0 FA rating(s) are green whileKRYS’s FA Score has 1 green FA rating(s).

  • APLS’s FA Score: 0 green, 5 red.
  • KRYS’s FA Score: 1 green, 4 red.
According to our system of comparison, KRYS is a better buy in the long-term than APLS.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

APLS’s TA Score shows that 5 TA indicator(s) are bullish while KRYS’s TA Score has 8 bullish TA indicator(s).

  • APLS’s TA Score: 5 bullish, 6 bearish.
  • KRYS’s TA Score: 8 bullish, 3 bearish.
According to our system of comparison, KRYS is a better buy in the short-term than APLS.

Price Growth

APLS (@Biotechnology) experienced а -8.19% price change this week, while KRYS (@Biotechnology) price change was +2.75% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +0.70%. For the same industry, the average monthly price growth was +13.93%, and the average quarterly price growth was +78.06%.

Reported Earning Dates

APLS is expected to report earnings on Nov 10, 2025.

KRYS is expected to report earnings on Nov 10, 2025.

Industries' Descriptions

@Biotechnology (+0.70% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
KRYS($5.44B) has a higher market cap than APLS($2.92B). KRYS YTD gains are higher at: 20.037 vs. APLS (-27.468). KRYS has higher annual earnings (EBITDA): 158M vs. APLS (-178.43M). KRYS has more cash in the bank: 682M vs. APLS (370M). KRYS has less debt than APLS: KRYS (9.68M) vs APLS (470M). APLS has higher revenues than KRYS: APLS (755M) vs KRYS (359M).
APLSKRYSAPLS / KRYS
Capitalization2.92B5.44B54%
EBITDA-178.43M158M-113%
Gain YTD-27.46820.037-137%
P/E RatioN/A38.22-
Revenue755M359M210%
Total Cash370M682M54%
Total Debt470M9.68M4,855%
FUNDAMENTALS RATINGS
APLS vs KRYS: Fundamental Ratings
APLS
KRYS
OUTLOOK RATING
1..100
723
VALUATION
overvalued / fair valued / undervalued
1..100
63
Fair valued
79
Overvalued
PROFIT vs RISK RATING
1..100
10029
SMR RATING
1..100
9954
PRICE GROWTH RATING
1..100
4842
P/E GROWTH RATING
1..100
10067
SEASONALITY SCORE
1..100
85n/a

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

APLS's Valuation (63) in the Medical Distributors industry is in the same range as KRYS (79) in the Pharmaceuticals Major industry. This means that APLS’s stock grew similarly to KRYS’s over the last 12 months.

KRYS's Profit vs Risk Rating (29) in the Pharmaceuticals Major industry is significantly better than the same rating for APLS (100) in the Medical Distributors industry. This means that KRYS’s stock grew significantly faster than APLS’s over the last 12 months.

KRYS's SMR Rating (54) in the Pharmaceuticals Major industry is somewhat better than the same rating for APLS (99) in the Medical Distributors industry. This means that KRYS’s stock grew somewhat faster than APLS’s over the last 12 months.

KRYS's Price Growth Rating (42) in the Pharmaceuticals Major industry is in the same range as APLS (48) in the Medical Distributors industry. This means that KRYS’s stock grew similarly to APLS’s over the last 12 months.

KRYS's P/E Growth Rating (67) in the Pharmaceuticals Major industry is somewhat better than the same rating for APLS (100) in the Medical Distributors industry. This means that KRYS’s stock grew somewhat faster than APLS’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
APLSKRYS
RSI
ODDS (%)
Bullish Trend 1 day ago
78%
Bearish Trend 1 day ago
71%
Stochastic
ODDS (%)
Bearish Trend 1 day ago
78%
Bearish Trend 1 day ago
80%
Momentum
ODDS (%)
Bullish Trend 1 day ago
77%
Bullish Trend 1 day ago
80%
MACD
ODDS (%)
Bullish Trend 1 day ago
77%
Bullish Trend 1 day ago
82%
TrendWeek
ODDS (%)
Bearish Trend 1 day ago
80%
Bullish Trend 1 day ago
78%
TrendMonth
ODDS (%)
Bearish Trend 1 day ago
85%
Bullish Trend 1 day ago
80%
Advances
ODDS (%)
Bullish Trend 8 days ago
81%
Bullish Trend 1 day ago
79%
Declines
ODDS (%)
Bearish Trend 1 day ago
80%
Bearish Trend 20 days ago
75%
BollingerBands
ODDS (%)
Bearish Trend 1 day ago
90%
Bullish Trend 6 days ago
82%
Aroon
ODDS (%)
Bearish Trend 1 day ago
84%
Bullish Trend 1 day ago
74%
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APLS
Daily Signalchanged days ago
Gain/Loss if bought
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KRYS
Daily Signalchanged days ago
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KRYS and

Correlation & Price change

A.I.dvisor indicates that over the last year, KRYS has been loosely correlated with VRDN. These tickers have moved in lockstep 53% of the time. This A.I.-generated data suggests there is some statistical probability that if KRYS jumps, then VRDN could also see price increases.

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Correlation
To KRYS
1D Price
Change %
KRYS100%
+1.79%
VRDN - KRYS
53%
Loosely correlated
-2.81%
XNCR - KRYS
51%
Loosely correlated
-11.03%
NUVL - KRYS
50%
Loosely correlated
-5.66%
CGON - KRYS
50%
Loosely correlated
-0.23%
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49%
Loosely correlated
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