CALC
Price
$3.16
Change
+$0.09 (+2.93%)
Updated
Nov 19, 04:59 PM (EDT)
Capitalization
45.48M
Intraday BUY SELL Signals
OBIO
Price
$4.65
Change
+$0.42 (+9.93%)
Updated
Nov 19, 04:59 PM (EDT)
Capitalization
263.13M
Intraday BUY SELL Signals
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CALC vs OBIO

Header iconCALC vs OBIO Comparison
Open Charts CALC vs OBIOBanner chart's image
CalciMedica
Price$3.16
Change+$0.09 (+2.93%)
Volume$5.56K
Capitalization45.48M
Orchestra BioMed Holdings
Price$4.65
Change+$0.42 (+9.93%)
Volume$4.68K
Capitalization263.13M
CALC vs OBIO Comparison Chart in %
CALC
Daily Signal:
Gain/Loss:
OBIO
Daily Signal:
Gain/Loss:
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VS
CALC vs. OBIO commentary
Nov 20, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is CALC is a Hold and OBIO is a Hold.

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COMPARISON
Comparison
Nov 20, 2025
Stock price -- (CALC: $3.16 vs. OBIO: $4.66)
Brand notoriety: CALC and OBIO are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: CALC: 191% vs. OBIO: 179%
Market capitalization -- CALC: $45.48M vs. OBIO: $263.13M
CALC [@Biotechnology] is valued at $45.48M. OBIO’s [@Biotechnology] market capitalization is $263.13M. The market cap for tickers in the [@Biotechnology] industry ranges from $106.82B to $0. The average market capitalization across the [@Biotechnology] industry is $2.15B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

CALC’s FA Score shows that 1 FA rating(s) are green whileOBIO’s FA Score has 0 green FA rating(s).

  • CALC’s FA Score: 1 green, 4 red.
  • OBIO’s FA Score: 0 green, 5 red.
According to our system of comparison, CALC is a better buy in the long-term than OBIO.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

CALC’s TA Score shows that 4 TA indicator(s) are bullish while OBIO’s TA Score has 3 bullish TA indicator(s).

  • CALC’s TA Score: 4 bullish, 5 bearish.
  • OBIO’s TA Score: 3 bullish, 5 bearish.
According to our system of comparison, both CALC and OBIO are a bad buy in the short-term.

Price Growth

CALC (@Biotechnology) experienced а -5.51% price change this week, while OBIO (@Biotechnology) price change was +5.43% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was -2.19%. For the same industry, the average monthly price growth was -5.74%, and the average quarterly price growth was +63.93%.

Industries' Descriptions

@Biotechnology (-2.19% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
OBIO($263M) has a higher market cap than CALC($45.5M). OBIO YTD gains are higher at: 16.500 vs. CALC (-10.847). CALC has higher annual earnings (EBITDA): -30.55M vs. OBIO (-70.94M). OBIO has more cash in the bank: 33.9M vs. CALC (18M). CALC has less debt than OBIO: CALC (8.5M) vs OBIO (16.4M). OBIO has higher revenues than CALC: OBIO (2.94M) vs CALC (0).
CALCOBIOCALC / OBIO
Capitalization45.5M263M17%
EBITDA-30.55M-70.94M43%
Gain YTD-10.84716.500-66%
P/E Ratio0.30N/A-
Revenue02.94M-
Total Cash18M33.9M53%
Total Debt8.5M16.4M52%
TECHNICAL ANALYSIS
Technical Analysis
CALCOBIO
RSI
ODDS (%)
N/A
Bearish Trend 2 days ago
48%
Stochastic
ODDS (%)
Bullish Trend 2 days ago
87%
Bearish Trend 2 days ago
71%
Momentum
ODDS (%)
Bullish Trend 2 days ago
76%
Bullish Trend 2 days ago
55%
MACD
ODDS (%)
Bullish Trend 2 days ago
88%
Bearish Trend 2 days ago
50%
TrendWeek
ODDS (%)
Bearish Trend 2 days ago
90%
Bullish Trend 2 days ago
52%
TrendMonth
ODDS (%)
Bearish Trend 2 days ago
89%
Bullish Trend 2 days ago
51%
Advances
ODDS (%)
Bullish Trend 8 days ago
77%
Bullish Trend 2 days ago
64%
Declines
ODDS (%)
Bearish Trend 6 days ago
88%
Bearish Trend 6 days ago
75%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 2 days ago
64%
Aroon
ODDS (%)
Bearish Trend 2 days ago
90%
Bullish Trend 2 days ago
62%
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CALC
Daily Signal:
Gain/Loss:
OBIO
Daily Signal:
Gain/Loss:
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CALC and

Correlation & Price change

A.I.dvisor tells us that CALC and OBIO have been poorly correlated (+33% of the time) for the last year. This A.I.-generated data suggests there is low statistical probability that CALC and OBIO's prices will move in lockstep.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To CALC
1D Price
Change %
CALC100%
+2.80%
OBIO - CALC
33%
Poorly correlated
+10.17%
MTNB - CALC
28%
Poorly correlated
-31.52%
ABOS - CALC
27%
Poorly correlated
-6.02%
ALDX - CALC
26%
Poorly correlated
-1.02%
VTYX - CALC
26%
Poorly correlated
-2.77%
More

OBIO and

Correlation & Price change

A.I.dvisor indicates that over the last year, OBIO has been loosely correlated with RXRX. These tickers have moved in lockstep 40% of the time. This A.I.-generated data suggests there is some statistical probability that if OBIO jumps, then RXRX could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To OBIO
1D Price
Change %
OBIO100%
+10.17%
RXRX - OBIO
40%
Loosely correlated
-3.12%
XBIT - OBIO
38%
Loosely correlated
-8.30%
RGNX - OBIO
37%
Loosely correlated
-2.84%
BEAM - OBIO
37%
Loosely correlated
-4.24%
OCUL - OBIO
37%
Loosely correlated
+2.81%
More