CALC
Price
$2.91
Change
+$0.30 (+11.49%)
Updated
Aug 15 closing price
Capitalization
40.66M
OBIO
Price
$2.56
Change
-$0.09 (-3.38%)
Updated
Aug 15 closing price
Capitalization
138.39M
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CALC vs OBIO

Header iconCALC vs OBIO Comparison
Open Charts CALC vs OBIOBanner chart's image
CalciMedica
Price$2.91
Change+$0.30 (+11.49%)
Volume$28.76K
Capitalization40.66M
Orchestra BioMed Holdings
Price$2.56
Change-$0.09 (-3.38%)
Volume$240.66K
Capitalization138.39M
CALC vs OBIO Comparison Chart in %
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CALC
Daily Signalchanged days ago
Gain/Loss if bought
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OBIO
Daily Signalchanged days ago
Gain/Loss if bought
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CALC vs. OBIO commentary
Aug 17, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is CALC is a Hold and OBIO is a Hold.

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COMPARISON
Comparison
Aug 17, 2025
Stock price -- (CALC: $2.91 vs. OBIO: $2.57)
Brand notoriety: CALC and OBIO are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: CALC: 38% vs. OBIO: 75%
Market capitalization -- CALC: $40.66M vs. OBIO: $138.39M
CALC [@Biotechnology] is valued at $40.66M. OBIO’s [@Biotechnology] market capitalization is $138.39M. The market cap for tickers in the [@Biotechnology] industry ranges from $100.71B to $0. The average market capitalization across the [@Biotechnology] industry is $1.88B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

CALC’s FA Score shows that 1 FA rating(s) are green whileOBIO’s FA Score has 0 green FA rating(s).

  • CALC’s FA Score: 1 green, 4 red.
  • OBIO’s FA Score: 0 green, 5 red.
According to our system of comparison, CALC is a better buy in the long-term than OBIO.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

CALC’s TA Score shows that 3 TA indicator(s) are bullish while OBIO’s TA Score has 5 bullish TA indicator(s).

  • CALC’s TA Score: 3 bullish, 4 bearish.
  • OBIO’s TA Score: 5 bullish, 5 bearish.
According to our system of comparison, OBIO is a better buy in the short-term than CALC.

Price Growth

CALC (@Biotechnology) experienced а +6.20% price change this week, while OBIO (@Biotechnology) price change was -5.35% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +9.90%. For the same industry, the average monthly price growth was +26.70%, and the average quarterly price growth was +20.91%.

Industries' Descriptions

@Biotechnology (+9.90% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
OBIO($138M) has a higher market cap than CALC($40.7M). CALC YTD gains are higher at: -17.797 vs. OBIO (-35.875). CALC has higher annual earnings (EBITDA): -28.87M vs. OBIO (-68.48M). OBIO has more cash in the bank: 49.9M vs. CALC (24.6M). CALC has less debt than OBIO: CALC (8.6M) vs OBIO (16.4M). OBIO has higher revenues than CALC: OBIO (2.89M) vs CALC (0).
CALCOBIOCALC / OBIO
Capitalization40.7M138M29%
EBITDA-28.87M-68.48M42%
Gain YTD-17.797-35.87550%
P/E Ratio0.30N/A-
Revenue02.89M-
Total Cash24.6M49.9M49%
Total Debt8.6M16.4M52%
TECHNICAL ANALYSIS
Technical Analysis
CALCOBIO
RSI
ODDS (%)
Bearish Trend 2 days ago
90%
Bullish Trend 2 days ago
79%
Stochastic
ODDS (%)
Bullish Trend 2 days ago
71%
Bullish Trend 2 days ago
56%
Momentum
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 2 days ago
58%
MACD
ODDS (%)
Bearish Trend 2 days ago
85%
Bearish Trend 2 days ago
47%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
74%
Bearish Trend 2 days ago
61%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
76%
Bearish Trend 2 days ago
62%
Advances
ODDS (%)
Bullish Trend 2 days ago
78%
Bullish Trend 20 days ago
61%
Declines
ODDS (%)
Bearish Trend 4 days ago
89%
Bearish Trend 10 days ago
73%
BollingerBands
ODDS (%)
N/A
Bullish Trend 2 days ago
60%
Aroon
ODDS (%)
Bullish Trend 2 days ago
72%
Bullish Trend 2 days ago
66%
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CALC
Daily Signalchanged days ago
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OBIO
Daily Signalchanged days ago
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CALC and

Correlation & Price change

A.I.dvisor tells us that CALC and OBIO have been poorly correlated (+33% of the time) for the last year. This A.I.-generated data suggests there is low statistical probability that CALC and OBIO's prices will move in lockstep.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To CALC
1D Price
Change %
CALC100%
+11.49%
OBIO - CALC
33%
Poorly correlated
-3.57%
THAR - CALC
31%
Poorly correlated
+2.27%
ALDX - CALC
26%
Poorly correlated
+1.70%
VTYX - CALC
26%
Poorly correlated
-5.67%
TRAW - CALC
26%
Poorly correlated
-6.79%
More