DNLI
Price
$16.94
Change
-$0.54 (-3.09%)
Updated
Nov 19, 04:59 PM (EDT)
Capitalization
2.56B
103 days until earnings call
Intraday BUY SELL Signals
LXRX
Price
$1.45
Change
-$0.02 (-1.36%)
Updated
Nov 19, 01:48 PM (EDT)
Capitalization
536.01M
119 days until earnings call
Intraday BUY SELL Signals
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DNLI vs LXRX

Header iconDNLI vs LXRX Comparison
Open Charts DNLI vs LXRXBanner chart's image
Denali Therapeutics
Price$16.94
Change-$0.54 (-3.09%)
Volume$33.8K
Capitalization2.56B
Lexicon Pharmaceuticals
Price$1.45
Change-$0.02 (-1.36%)
Volume$300
Capitalization536.01M
DNLI vs LXRX Comparison Chart in %
DNLI
Daily Signal:
Gain/Loss:
LXRX
Daily Signal:
Gain/Loss:
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VS
DNLI vs. LXRX commentary
Nov 19, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is DNLI is a Hold and LXRX is a Hold.

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COMPARISON
Comparison
Nov 19, 2025
Stock price -- (DNLI: $17.47 vs. LXRX: $1.48)
Brand notoriety: DNLI and LXRX are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: DNLI: 50% vs. LXRX: 52%
Market capitalization -- DNLI: $2.56B vs. LXRX: $536.01M
DNLI [@Biotechnology] is valued at $2.56B. LXRX’s [@Biotechnology] market capitalization is $536.01M. The market cap for tickers in the [@Biotechnology] industry ranges from $110.5B to $0. The average market capitalization across the [@Biotechnology] industry is $2.15B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

DNLI’s FA Score shows that 0 FA rating(s) are green whileLXRX’s FA Score has 1 green FA rating(s).

  • DNLI’s FA Score: 0 green, 5 red.
  • LXRX’s FA Score: 1 green, 4 red.
According to our system of comparison, LXRX is a better buy in the long-term than DNLI.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

DNLI’s TA Score shows that 6 TA indicator(s) are bullish while LXRX’s TA Score has 4 bullish TA indicator(s).

  • DNLI’s TA Score: 6 bullish, 4 bearish.
  • LXRX’s TA Score: 4 bullish, 4 bearish.
According to our system of comparison, DNLI is a better buy in the short-term than LXRX.

Price Growth

DNLI (@Biotechnology) experienced а -0.63% price change this week, while LXRX (@Biotechnology) price change was -5.45% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was -2.17%. For the same industry, the average monthly price growth was -5.68%, and the average quarterly price growth was +64.91%.

Reported Earning Dates

DNLI is expected to report earnings on Mar 02, 2026.

LXRX is expected to report earnings on Mar 18, 2026.

Industries' Descriptions

@Biotechnology (-2.17% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
DNLI($2.56B) has a higher market cap than LXRX($536M). LXRX YTD gains are higher at: 99.729 vs. DNLI (-14.279). LXRX has higher annual earnings (EBITDA): -107.44M vs. DNLI (-521.52M). DNLI has more cash in the bank: 899M vs. LXRX (139M). DNLI has less debt than LXRX: DNLI (46.6M) vs LXRX (57M). LXRX has higher revenues than DNLI: LXRX (58.4M) vs DNLI (0).
DNLILXRXDNLI / LXRX
Capitalization2.56B536M478%
EBITDA-521.52M-107.44M485%
Gain YTD-14.27999.729-14%
P/E RatioN/AN/A-
Revenue058.4M-
Total Cash899M139M647%
Total Debt46.6M57M82%
FUNDAMENTALS RATINGS
DNLI vs LXRX: Fundamental Ratings
DNLI
LXRX
OUTLOOK RATING
1..100
7410
VALUATION
overvalued / fair valued / undervalued
1..100
93
Overvalued
62
Fair valued
PROFIT vs RISK RATING
1..100
10098
SMR RATING
1..100
9596
PRICE GROWTH RATING
1..100
4837
P/E GROWTH RATING
1..100
9916
SEASONALITY SCORE
1..100
5030

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

LXRX's Valuation (62) in the Biotechnology industry is in the same range as DNLI (93). This means that LXRX’s stock grew similarly to DNLI’s over the last 12 months.

LXRX's Profit vs Risk Rating (98) in the Biotechnology industry is in the same range as DNLI (100). This means that LXRX’s stock grew similarly to DNLI’s over the last 12 months.

DNLI's SMR Rating (95) in the Biotechnology industry is in the same range as LXRX (96). This means that DNLI’s stock grew similarly to LXRX’s over the last 12 months.

LXRX's Price Growth Rating (37) in the Biotechnology industry is in the same range as DNLI (48). This means that LXRX’s stock grew similarly to DNLI’s over the last 12 months.

LXRX's P/E Growth Rating (16) in the Biotechnology industry is significantly better than the same rating for DNLI (99). This means that LXRX’s stock grew significantly faster than DNLI’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
DNLILXRX
RSI
ODDS (%)
Bearish Trend 2 days ago
86%
N/A
Stochastic
ODDS (%)
Bearish Trend 2 days ago
89%
Bearish Trend 2 days ago
84%
Momentum
ODDS (%)
Bullish Trend 2 days ago
86%
Bullish Trend 2 days ago
84%
MACD
ODDS (%)
Bullish Trend 2 days ago
76%
Bullish Trend 2 days ago
90%
TrendWeek
ODDS (%)
Bearish Trend 2 days ago
85%
Bearish Trend 2 days ago
85%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
72%
Bullish Trend 2 days ago
88%
Advances
ODDS (%)
Bullish Trend 9 days ago
75%
Bullish Trend 9 days ago
86%
Declines
ODDS (%)
Bearish Trend 7 days ago
82%
Bearish Trend 7 days ago
84%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
85%
Bearish Trend 2 days ago
84%
Aroon
ODDS (%)
Bullish Trend 2 days ago
66%
Bearish Trend 2 days ago
90%
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DNLI
Daily Signal:
Gain/Loss:
LXRX
Daily Signal:
Gain/Loss:
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Correlation & Price change

A.I.dvisor indicates that over the last year, LXRX has been loosely correlated with PLRX. These tickers have moved in lockstep 38% of the time. This A.I.-generated data suggests there is some statistical probability that if LXRX jumps, then PLRX could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To LXRX
1D Price
Change %
LXRX100%
+1.03%
PLRX - LXRX
38%
Loosely correlated
-5.45%
OCUL - LXRX
38%
Loosely correlated
-1.09%
VCYT - LXRX
37%
Loosely correlated
-1.35%
ABOS - LXRX
35%
Loosely correlated
+4.43%
DNLI - LXRX
34%
Loosely correlated
+0.58%
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