DNLI
Price
$14.39
Change
-$0.03 (-0.21%)
Updated
Jun 5, 04:16 PM (EDT)
Capitalization
2.09B
56 days until earnings call
PRTA
Price
$5.06
Change
+$0.18 (+3.69%)
Updated
Jun 5, 04:36 PM (EDT)
Capitalization
262.68M
63 days until earnings call
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DNLI vs PRTA

Header iconDNLI vs PRTA Comparison
Open Charts DNLI vs PRTABanner chart's image
Denali Therapeutics
Price$14.39
Change-$0.03 (-0.21%)
Volume$100
Capitalization2.09B
Prothena
Price$5.06
Change+$0.18 (+3.69%)
Volume$1.45K
Capitalization262.68M
DNLI vs PRTA Comparison Chart
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DNLI
Daily Signalchanged days ago
Gain/Loss if bought
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PRTA
Daily Signalchanged days ago
Gain/Loss if bought
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DNLI vs. PRTA commentary
Jun 05, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is DNLI is a Hold and PRTA is a StrongBuy.

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COMPARISON
Comparison
Jun 05, 2025
Stock price -- (DNLI: $14.42 vs. PRTA: $4.88)
Brand notoriety: DNLI and PRTA are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: DNLI: 133% vs. PRTA: 77%
Market capitalization -- DNLI: $2.09B vs. PRTA: $262.68M
DNLI [@Biotechnology] is valued at $2.09B. PRTA’s [@Biotechnology] market capitalization is $262.68M. The market cap for tickers in the [@Biotechnology] industry ranges from $318.09B to $0. The average market capitalization across the [@Biotechnology] industry is $2.31B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

DNLI’s FA Score shows that 0 FA rating(s) are green whilePRTA’s FA Score has 0 green FA rating(s).

  • DNLI’s FA Score: 0 green, 5 red.
  • PRTA’s FA Score: 0 green, 5 red.
According to our system of comparison, DNLI is a better buy in the long-term than PRTA.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

DNLI’s TA Score shows that 4 TA indicator(s) are bullish while PRTA’s TA Score has 4 bullish TA indicator(s).

  • DNLI’s TA Score: 4 bullish, 5 bearish.
  • PRTA’s TA Score: 4 bullish, 3 bearish.
According to our system of comparison, PRTA is a better buy in the short-term than DNLI.

Price Growth

DNLI (@Biotechnology) experienced а +10.68% price change this week, while PRTA (@Biotechnology) price change was +6.55% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +4.11%. For the same industry, the average monthly price growth was +9.95%, and the average quarterly price growth was -2.16%.

Reported Earning Dates

DNLI is expected to report earnings on Jul 31, 2025.

PRTA is expected to report earnings on Aug 07, 2025.

Industries' Descriptions

@Biotechnology (+4.11% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
DNLI($2.1B) has a higher market cap than PRTA($263M). DNLI YTD gains are higher at: -29.244 vs. PRTA (-64.765). PRTA has higher annual earnings (EBITDA): -137.71M vs. DNLI (-505.16M). DNLI has more cash in the bank: 818M vs. PRTA (418M). PRTA has less debt than DNLI: PRTA (10.2M) vs DNLI (48.6M). PRTA has higher revenues than DNLI: PRTA (138M) vs DNLI (0).
DNLIPRTADNLI / PRTA
Capitalization2.1B263M797%
EBITDA-505.16M-137.71M367%
Gain YTD-29.244-64.76545%
P/E RatioN/AN/A-
Revenue0138M-
Total Cash818M418M196%
Total Debt48.6M10.2M476%
FUNDAMENTALS RATINGS
DNLI vs PRTA: Fundamental Ratings
DNLI
PRTA
OUTLOOK RATING
1..100
602
VALUATION
overvalued / fair valued / undervalued
1..100
93
Overvalued
56
Fair valued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
4090
PRICE GROWTH RATING
1..100
8897
P/E GROWTH RATING
1..100
9894
SEASONALITY SCORE
1..100
5045

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

PRTA's Valuation (56) in the Biotechnology industry is somewhat better than the same rating for DNLI (93). This means that PRTA’s stock grew somewhat faster than DNLI’s over the last 12 months.

PRTA's Profit vs Risk Rating (100) in the Biotechnology industry is in the same range as DNLI (100). This means that PRTA’s stock grew similarly to DNLI’s over the last 12 months.

DNLI's SMR Rating (40) in the Biotechnology industry is somewhat better than the same rating for PRTA (90). This means that DNLI’s stock grew somewhat faster than PRTA’s over the last 12 months.

DNLI's Price Growth Rating (88) in the Biotechnology industry is in the same range as PRTA (97). This means that DNLI’s stock grew similarly to PRTA’s over the last 12 months.

PRTA's P/E Growth Rating (94) in the Biotechnology industry is in the same range as DNLI (98). This means that PRTA’s stock grew similarly to DNLI’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
DNLIPRTA
RSI
ODDS (%)
Bearish Trend 3 days ago
81%
Bullish Trend 2 days ago
77%
Stochastic
ODDS (%)
Bearish Trend 2 days ago
81%
Bullish Trend 2 days ago
79%
Momentum
ODDS (%)
Bullish Trend 2 days ago
77%
N/A
MACD
ODDS (%)
Bullish Trend 2 days ago
86%
Bearish Trend 2 days ago
82%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
78%
Bullish Trend 2 days ago
79%
TrendMonth
ODDS (%)
Bearish Trend 2 days ago
85%
Bearish Trend 2 days ago
88%
Advances
ODDS (%)
Bullish Trend 17 days ago
78%
Bullish Trend 2 days ago
75%
Declines
ODDS (%)
Bearish Trend 9 days ago
80%
Bearish Trend 10 days ago
87%
BollingerBands
ODDS (%)
N/A
Bullish Trend 2 days ago
68%
Aroon
ODDS (%)
Bearish Trend 2 days ago
83%
Bearish Trend 2 days ago
87%
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DNLI
Daily Signalchanged days ago
Gain/Loss if bought
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PRTA
Daily Signalchanged days ago
Gain/Loss if bought
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DNLI and

Correlation & Price change

A.I.dvisor indicates that over the last year, DNLI has been loosely correlated with NRIX. These tickers have moved in lockstep 56% of the time. This A.I.-generated data suggests there is some statistical probability that if DNLI jumps, then NRIX could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To DNLI
1D Price
Change %
DNLI100%
+3.52%
NRIX - DNLI
56%
Loosely correlated
+0.66%
BEAM - DNLI
55%
Loosely correlated
+1.60%
ARWR - DNLI
54%
Loosely correlated
+0.78%
RGNX - DNLI
54%
Loosely correlated
-0.49%
DAWN - DNLI
52%
Loosely correlated
-0.72%
More

PRTA and

Correlation & Price change

A.I.dvisor indicates that over the last year, PRTA has been loosely correlated with RCKT. These tickers have moved in lockstep 54% of the time. This A.I.-generated data suggests there is some statistical probability that if PRTA jumps, then RCKT could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To PRTA
1D Price
Change %
PRTA100%
+1.04%
RCKT - PRTA
54%
Loosely correlated
-1.35%
DNLI - PRTA
44%
Loosely correlated
+3.52%
KRYS - PRTA
40%
Loosely correlated
+0.86%
RVMD - PRTA
39%
Loosely correlated
-0.49%
AXON - PRTA
38%
Loosely correlated
+2.76%
More