GOSS
Price
$2.48
Change
+$0.39 (+18.66%)
Updated
Oct 24 closing price
Capitalization
567.62M
12 days until earnings call
Intraday Buy/Sell Signals
SYRE
Price
$23.37
Change
+$1.00 (+4.47%)
Updated
Oct 24 closing price
Capitalization
1.81B
12 days until earnings call
Intraday Buy/Sell Signals
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GOSS vs SYRE

Header iconGOSS vs SYRE Comparison
Open Charts GOSS vs SYREBanner chart's image
Gossamer Bio
Price$2.48
Change+$0.39 (+18.66%)
Volume$7.74M
Capitalization567.62M
Spyre Therapeutics
Price$23.37
Change+$1.00 (+4.47%)
Volume$700.7K
Capitalization1.81B
GOSS vs SYRE Comparison Chart in %
GOSS
Daily Signalchanged days ago
Gain/Loss if bought
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SYRE
Daily Signalchanged days ago
Gain/Loss if bought
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GOSS vs. SYRE commentary
Oct 25, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is GOSS is a Hold and SYRE is a Buy.

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COMPARISON
Comparison
Oct 25, 2025
Stock price -- (GOSS: $2.48 vs. SYRE: $23.37)
Brand notoriety: GOSS and SYRE are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: GOSS: 187% vs. SYRE: 78%
Market capitalization -- GOSS: $567.62M vs. SYRE: $1.81B
GOSS [@Biotechnology] is valued at $567.62M. SYRE’s [@Biotechnology] market capitalization is $1.81B. The market cap for tickers in the [@Biotechnology] industry ranges from $108.04B to $0. The average market capitalization across the [@Biotechnology] industry is $2.04B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

GOSS’s FA Score shows that 0 FA rating(s) are green whileSYRE’s FA Score has 0 green FA rating(s).

  • GOSS’s FA Score: 0 green, 5 red.
  • SYRE’s FA Score: 0 green, 5 red.
According to our system of comparison, both GOSS and SYRE are a bad buy in the long-term.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

GOSS’s TA Score shows that 3 TA indicator(s) are bullish while SYRE’s TA Score has 7 bullish TA indicator(s).

  • GOSS’s TA Score: 3 bullish, 5 bearish.
  • SYRE’s TA Score: 7 bullish, 4 bearish.
According to our system of comparison, SYRE is a better buy in the short-term than GOSS.

Price Growth

GOSS (@Biotechnology) experienced а +13.24% price change this week, while SYRE (@Biotechnology) price change was +4.01% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +0.97%. For the same industry, the average monthly price growth was +11.13%, and the average quarterly price growth was +63.98%.

Reported Earning Dates

GOSS is expected to report earnings on Nov 06, 2025.

SYRE is expected to report earnings on Nov 06, 2025.

Industries' Descriptions

@Biotechnology (+0.97% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
SYRE($1.81B) has a higher market cap than GOSS($568M). GOSS YTD gains are higher at: 174.154 vs. SYRE (0.387). GOSS has higher annual earnings (EBITDA): -128.6M vs. SYRE (-222.15M). SYRE has more cash in the bank: 527M vs. GOSS (213M). SYRE has less debt than GOSS: SYRE (0) vs GOSS (203M). GOSS has higher revenues than SYRE: GOSS (40.2M) vs SYRE (0).
GOSSSYREGOSS / SYRE
Capitalization568M1.81B31%
EBITDA-128.6M-222.15M58%
Gain YTD174.1540.38745,048%
P/E RatioN/A1.72-
Revenue40.2M0-
Total Cash213M527M40%
Total Debt203M0-
FUNDAMENTALS RATINGS
GOSS vs SYRE: Fundamental Ratings
GOSS
SYRE
OUTLOOK RATING
1..100
5427
VALUATION
overvalued / fair valued / undervalued
1..100
50
Fair valued
50
Fair valued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
10098
PRICE GROWTH RATING
1..100
4039
P/E GROWTH RATING
1..100
10082
SEASONALITY SCORE
1..100
5023

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

GOSS's Valuation (50) in the Pharmaceuticals Major industry is in the same range as SYRE (50). This means that GOSS’s stock grew similarly to SYRE’s over the last 12 months.

GOSS's Profit vs Risk Rating (100) in the Pharmaceuticals Major industry is in the same range as SYRE (100). This means that GOSS’s stock grew similarly to SYRE’s over the last 12 months.

SYRE's SMR Rating (98) in the Pharmaceuticals Major industry is in the same range as GOSS (100). This means that SYRE’s stock grew similarly to GOSS’s over the last 12 months.

SYRE's Price Growth Rating (39) in the Pharmaceuticals Major industry is in the same range as GOSS (40). This means that SYRE’s stock grew similarly to GOSS’s over the last 12 months.

SYRE's P/E Growth Rating (82) in the Pharmaceuticals Major industry is in the same range as GOSS (100). This means that SYRE’s stock grew similarly to GOSS’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
GOSSSYRE
RSI
ODDS (%)
N/A
Bearish Trend 2 days ago
90%
Stochastic
ODDS (%)
Bullish Trend 2 days ago
87%
Bearish Trend 2 days ago
90%
Momentum
ODDS (%)
Bullish Trend 2 days ago
81%
Bullish Trend 2 days ago
77%
MACD
ODDS (%)
Bearish Trend 5 days ago
89%
Bullish Trend 2 days ago
80%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
85%
Bullish Trend 2 days ago
83%
TrendMonth
ODDS (%)
Bearish Trend 2 days ago
89%
Bullish Trend 2 days ago
82%
Advances
ODDS (%)
N/A
Bullish Trend 2 days ago
83%
Declines
ODDS (%)
Bearish Trend 9 days ago
86%
Bearish Trend 4 days ago
90%
BollingerBands
ODDS (%)
Bullish Trend 2 days ago
89%
Bearish Trend 2 days ago
90%
Aroon
ODDS (%)
Bearish Trend 2 days ago
87%
Bullish Trend 2 days ago
79%
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GOSS
Daily Signalchanged days ago
Gain/Loss if bought
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SYRE
Daily Signalchanged days ago
Gain/Loss if bought
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GOSS and

Correlation & Price change

A.I.dvisor indicates that over the last year, GOSS has been loosely correlated with LITS. These tickers have moved in lockstep 46% of the time. This A.I.-generated data suggests there is some statistical probability that if GOSS jumps, then LITS could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To GOSS
1D Price
Change %
GOSS100%
+18.66%
LITS - GOSS
46%
Loosely correlated
+3.74%
APVO - GOSS
41%
Loosely correlated
-0.65%
ABEO - GOSS
40%
Loosely correlated
+1.11%
AUPH - GOSS
37%
Loosely correlated
+2.68%
CHRS - GOSS
36%
Loosely correlated
-1.20%
More

SYRE and

Correlation & Price change

A.I.dvisor indicates that over the last year, SYRE has been loosely correlated with BHVN. These tickers have moved in lockstep 58% of the time. This A.I.-generated data suggests there is some statistical probability that if SYRE jumps, then BHVN could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SYRE
1D Price
Change %
SYRE100%
+4.47%
BHVN - SYRE
58%
Loosely correlated
+1.84%
CGON - SYRE
58%
Loosely correlated
+4.03%
APGE - SYRE
58%
Loosely correlated
-0.93%
IDYA - SYRE
56%
Loosely correlated
+2.67%
VRDN - SYRE
55%
Loosely correlated
+0.41%
More