IOVA
Price
$1.81
Change
-$0.02 (-1.09%)
Updated
Jun 5, 10:55 AM (EDT)
Capitalization
611.1M
63 days until earnings call
SPRO
Price
$2.62
Change
-$0.04 (-1.50%)
Updated
Jun 5, 01:21 PM (EDT)
Capitalization
148.72M
63 days until earnings call
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IOVA vs SPRO

Header iconIOVA vs SPRO Comparison
Open Charts IOVA vs SPROBanner chart's image
Iovance Biotherapeutics
Price$1.81
Change-$0.02 (-1.09%)
Volume$3.4K
Capitalization611.1M
Spero Therapeutics
Price$2.62
Change-$0.04 (-1.50%)
Volume$386
Capitalization148.72M
IOVA vs SPRO Comparison Chart
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IOVA
Daily Signalchanged days ago
Gain/Loss if bought
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SPRO
Daily Signalchanged days ago
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IOVA vs. SPRO commentary
Jun 05, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is IOVA is a Buy and SPRO is a Hold.

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COMPARISON
Comparison
Jun 05, 2025
Stock price -- (IOVA: $1.83 vs. SPRO: $2.66)
Brand notoriety: IOVA and SPRO are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: IOVA: 42% vs. SPRO: 52%
Market capitalization -- IOVA: $611.1M vs. SPRO: $148.72M
IOVA [@Biotechnology] is valued at $611.1M. SPRO’s [@Biotechnology] market capitalization is $148.72M. The market cap for tickers in the [@Biotechnology] industry ranges from $318.09B to $0. The average market capitalization across the [@Biotechnology] industry is $2.31B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

IOVA’s FA Score shows that 1 FA rating(s) are green whileSPRO’s FA Score has 1 green FA rating(s).

  • IOVA’s FA Score: 1 green, 4 red.
  • SPRO’s FA Score: 1 green, 4 red.
According to our system of comparison, SPRO is a better buy in the long-term than IOVA.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

IOVA’s TA Score shows that 6 TA indicator(s) are bullish while SPRO’s TA Score has 5 bullish TA indicator(s).

  • IOVA’s TA Score: 6 bullish, 2 bearish.
  • SPRO’s TA Score: 5 bullish, 4 bearish.
According to our system of comparison, IOVA is a better buy in the short-term than SPRO.

Price Growth

IOVA (@Biotechnology) experienced а +5.78% price change this week, while SPRO (@Biotechnology) price change was +13.19% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +5.05%. For the same industry, the average monthly price growth was +10.91%, and the average quarterly price growth was -1.52%.

Reported Earning Dates

IOVA is expected to report earnings on Aug 07, 2025.

SPRO is expected to report earnings on Aug 07, 2025.

Industries' Descriptions

@Biotechnology (+5.05% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
IOVA($611M) has a higher market cap than SPRO($149M). SPRO YTD gains are higher at: 158.252 vs. IOVA (-75.270). SPRO has higher annual earnings (EBITDA): -2.45M vs. IOVA (-354.01M). IOVA has more cash in the bank: 360M vs. SPRO (76.3M). SPRO has less debt than IOVA: SPRO (4.62M) vs IOVA (53.7M). IOVA has higher revenues than SPRO: IOVA (213M) vs SPRO (89.9M).
IOVASPROIOVA / SPRO
Capitalization611M149M410%
EBITDA-354.01M-2.45M14,467%
Gain YTD-75.270158.252-48%
P/E RatioN/A10.75-
Revenue213M89.9M237%
Total Cash360M76.3M472%
Total Debt53.7M4.62M1,162%
FUNDAMENTALS RATINGS
IOVA vs SPRO: Fundamental Ratings
IOVA
SPRO
OUTLOOK RATING
1..100
533
VALUATION
overvalued / fair valued / undervalued
1..100
24
Undervalued
57
Fair valued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
9465
PRICE GROWTH RATING
1..100
9834
P/E GROWTH RATING
1..100
1005
SEASONALITY SCORE
1..100
n/an/a

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

IOVA's Valuation (24) in the Biotechnology industry is somewhat better than the same rating for SPRO (57) in the Pharmaceuticals Major industry. This means that IOVA’s stock grew somewhat faster than SPRO’s over the last 12 months.

IOVA's Profit vs Risk Rating (100) in the Biotechnology industry is in the same range as SPRO (100) in the Pharmaceuticals Major industry. This means that IOVA’s stock grew similarly to SPRO’s over the last 12 months.

SPRO's SMR Rating (65) in the Pharmaceuticals Major industry is in the same range as IOVA (94) in the Biotechnology industry. This means that SPRO’s stock grew similarly to IOVA’s over the last 12 months.

SPRO's Price Growth Rating (34) in the Pharmaceuticals Major industry is somewhat better than the same rating for IOVA (98) in the Biotechnology industry. This means that SPRO’s stock grew somewhat faster than IOVA’s over the last 12 months.

SPRO's P/E Growth Rating (5) in the Pharmaceuticals Major industry is significantly better than the same rating for IOVA (100) in the Biotechnology industry. This means that SPRO’s stock grew significantly faster than IOVA’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
IOVASPRO
RSI
ODDS (%)
Bullish Trend 2 days ago
78%
Bearish Trend 2 days ago
86%
Stochastic
ODDS (%)
Bullish Trend 2 days ago
82%
Bearish Trend 2 days ago
86%
Momentum
ODDS (%)
Bearish Trend 2 days ago
83%
Bullish Trend 2 days ago
79%
MACD
ODDS (%)
Bullish Trend 2 days ago
77%
Bullish Trend 2 days ago
77%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
81%
Bullish Trend 2 days ago
73%
TrendMonth
ODDS (%)
Bearish Trend 2 days ago
87%
Bullish Trend 2 days ago
75%
Advances
ODDS (%)
Bullish Trend 2 days ago
80%
Bullish Trend 4 days ago
71%
Declines
ODDS (%)
Bearish Trend 15 days ago
88%
Bearish Trend 29 days ago
90%
BollingerBands
ODDS (%)
Bullish Trend 2 days ago
77%
Bearish Trend 2 days ago
74%
Aroon
ODDS (%)
Bullish Trend 2 days ago
79%
N/A
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IOVA
Daily Signalchanged days ago
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SPRO
Daily Signalchanged days ago
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