KALA
Price
$5.25
Change
+$0.56 (+11.91%)
Updated
Jun 26 closing price
Capitalization
33.91M
SYRE
Price
$16.02
Change
+$0.61 (+3.96%)
Updated
Jun 26 closing price
Capitalization
966.86M
34 days until earnings call
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KALA vs SYRE

Header iconKALA vs SYRE Comparison
Open Charts KALA vs SYREBanner chart's image
Kala BIO
Price$5.25
Change+$0.56 (+11.91%)
Volume$138.14K
Capitalization33.91M
Spyre Therapeutics
Price$16.02
Change+$0.61 (+3.96%)
Volume$567.93K
Capitalization966.86M
KALA vs SYRE Comparison Chart in %
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KALA
Daily Signalchanged days ago
Gain/Loss if bought
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SYRE
Daily Signalchanged days ago
Gain/Loss if bought
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KALA vs. SYRE commentary
Jun 27, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is KALA is a Buy and SYRE is a Buy.

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COMPARISON
Comparison
Jun 27, 2025
Stock price -- (KALA: $5.26 vs. SYRE: $16.02)
Brand notoriety: KALA and SYRE are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: KALA: 184% vs. SYRE: 109%
Market capitalization -- KALA: $33.91M vs. SYRE: $966.86M
KALA [@Biotechnology] is valued at $33.91M. SYRE’s [@Biotechnology] market capitalization is $966.86M. The market cap for tickers in the [@Biotechnology] industry ranges from $301.01B to $0. The average market capitalization across the [@Biotechnology] industry is $2.32B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

KALA’s FA Score shows that 0 FA rating(s) are green whileSYRE’s FA Score has 0 green FA rating(s).

  • KALA’s FA Score: 0 green, 5 red.
  • SYRE’s FA Score: 0 green, 5 red.
According to our system of comparison, KALA is a better buy in the long-term than SYRE.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

KALA’s TA Score shows that 7 TA indicator(s) are bullish while SYRE’s TA Score has 5 bullish TA indicator(s).

  • KALA’s TA Score: 7 bullish, 3 bearish.
  • SYRE’s TA Score: 5 bullish, 5 bearish.
According to our system of comparison, KALA is a better buy in the short-term than SYRE.

Price Growth

KALA (@Biotechnology) experienced а +23.94% price change this week, while SYRE (@Biotechnology) price change was +6.23% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +3.59%. For the same industry, the average monthly price growth was +34.25%, and the average quarterly price growth was +14.95%.

Reported Earning Dates

KALA is expected to report earnings on Mar 31, 2025.

SYRE is expected to report earnings on Jul 31, 2025.

Industries' Descriptions

@Biotechnology (+3.59% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
SYRE($967M) has a higher market cap than KALA($33.9M). KALA YTD gains are higher at: -24.280 vs. SYRE (-31.186). KALA has higher annual earnings (EBITDA): -29.97M vs. SYRE (-214.36M). SYRE has more cash in the bank: 565M vs. KALA (42.2M). SYRE has less debt than KALA: SYRE (0) vs KALA (32.3M). KALA (0) and SYRE (0) have equivalent revenues.
KALASYREKALA / SYRE
Capitalization33.9M967M4%
EBITDA-29.97M-214.36M14%
Gain YTD-24.280-31.18678%
P/E RatioN/A1.72-
Revenue00-
Total Cash42.2M565M7%
Total Debt32.3M0-
FUNDAMENTALS RATINGS
KALA vs SYRE: Fundamental Ratings
KALA
SYRE
OUTLOOK RATING
1..100
556
VALUATION
overvalued / fair valued / undervalued
1..100
64
Fair valued
75
Overvalued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
10098
PRICE GROWTH RATING
1..100
6163
P/E GROWTH RATING
1..100
9883
SEASONALITY SCORE
1..100
n/an/a

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

KALA's Valuation (64) in the Pharmaceuticals Major industry is in the same range as SYRE (75). This means that KALA’s stock grew similarly to SYRE’s over the last 12 months.

KALA's Profit vs Risk Rating (100) in the Pharmaceuticals Major industry is in the same range as SYRE (100). This means that KALA’s stock grew similarly to SYRE’s over the last 12 months.

SYRE's SMR Rating (98) in the Pharmaceuticals Major industry is in the same range as KALA (100). This means that SYRE’s stock grew similarly to KALA’s over the last 12 months.

KALA's Price Growth Rating (61) in the Pharmaceuticals Major industry is in the same range as SYRE (63). This means that KALA’s stock grew similarly to SYRE’s over the last 12 months.

SYRE's P/E Growth Rating (83) in the Pharmaceuticals Major industry is in the same range as KALA (98). This means that SYRE’s stock grew similarly to KALA’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
KALASYRE
RSI
ODDS (%)
Bearish Trend 1 day ago
87%
Bearish Trend 1 day ago
88%
Stochastic
ODDS (%)
Bullish Trend 1 day ago
85%
Bullish Trend 1 day ago
85%
Momentum
ODDS (%)
Bullish Trend 1 day ago
88%
Bearish Trend 1 day ago
89%
MACD
ODDS (%)
Bullish Trend 1 day ago
76%
Bearish Trend 1 day ago
90%
TrendWeek
ODDS (%)
Bullish Trend 1 day ago
79%
Bullish Trend 1 day ago
84%
TrendMonth
ODDS (%)
Bullish Trend 1 day ago
75%
Bullish Trend 1 day ago
84%
Advances
ODDS (%)
Bullish Trend 1 day ago
76%
Bullish Trend 3 days ago
85%
Declines
ODDS (%)
Bearish Trend 5 days ago
90%
Bearish Trend 5 days ago
90%
BollingerBands
ODDS (%)
Bearish Trend 1 day ago
90%
Bearish Trend 1 day ago
90%
Aroon
ODDS (%)
Bullish Trend 1 day ago
75%
Bullish Trend 1 day ago
89%
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KALA
Daily Signalchanged days ago
Gain/Loss if bought
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SYRE
Daily Signalchanged days ago
Gain/Loss if bought
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KALA and

Correlation & Price change

A.I.dvisor tells us that KALA and PALI have been poorly correlated (+31% of the time) for the last year. This A.I.-generated data suggests there is low statistical probability that KALA and PALI's prices will move in lockstep.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To KALA
1D Price
Change %
KALA100%
+11.81%
PALI - KALA
31%
Poorly correlated
-1.64%
ARDX - KALA
28%
Poorly correlated
+1.52%
PMVP - KALA
28%
Poorly correlated
-0.92%
SYRE - KALA
28%
Poorly correlated
+3.96%
ENTX - KALA
27%
Poorly correlated
+1.52%
More

SYRE and

Correlation & Price change

A.I.dvisor indicates that over the last year, SYRE has been loosely correlated with CGON. These tickers have moved in lockstep 58% of the time. This A.I.-generated data suggests there is some statistical probability that if SYRE jumps, then CGON could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SYRE
1D Price
Change %
SYRE100%
+3.96%
CGON - SYRE
58%
Loosely correlated
+0.04%
BEAM - SYRE
57%
Loosely correlated
+2.27%
IMNM - SYRE
56%
Loosely correlated
+1.27%
IDYA - SYRE
53%
Loosely correlated
+1.27%
ACLX - SYRE
53%
Loosely correlated
+1.16%
More