KALV
Price
$13.38
Change
-$0.12 (-0.89%)
Updated
Sep 17 closing price
Capitalization
676M
77 days until earnings call
SYRE
Price
$15.09
Change
+$0.27 (+1.82%)
Updated
Sep 17, 04:59 PM (EDT)
Capitalization
895.14M
50 days until earnings call
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KALV vs SYRE

Header iconKALV vs SYRE Comparison
Open Charts KALV vs SYREBanner chart's image
KalVista Pharmaceuticals
Price$13.38
Change-$0.12 (-0.89%)
Volume$606.39K
Capitalization676M
Spyre Therapeutics
Price$15.09
Change+$0.27 (+1.82%)
Volume$23.73K
Capitalization895.14M
KALV vs SYRE Comparison Chart in %
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KALV
Daily Signalchanged days ago
Gain/Loss if bought
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SYRE
Daily Signalchanged days ago
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KALV vs. SYRE commentary
Sep 18, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is KALV is a StrongBuy and SYRE is a Buy.

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COMPARISON
Comparison
Sep 18, 2025
Stock price -- (KALV: $13.38 vs. SYRE: $15.09)
Brand notoriety: KALV and SYRE are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: KALV: 55% vs. SYRE: 154%
Market capitalization -- KALV: $676M vs. SYRE: $895.14M
KALV [@Biotechnology] is valued at $676M. SYRE’s [@Biotechnology] market capitalization is $895.14M. The market cap for tickers in the [@Biotechnology] industry ranges from $100.34B to $0. The average market capitalization across the [@Biotechnology] industry is $1.89B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

KALV’s FA Score shows that 0 FA rating(s) are green whileSYRE’s FA Score has 0 green FA rating(s).

  • KALV’s FA Score: 0 green, 5 red.
  • SYRE’s FA Score: 0 green, 5 red.
According to our system of comparison, KALV is a better buy in the long-term than SYRE.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

KALV’s TA Score shows that 4 TA indicator(s) are bullish while SYRE’s TA Score has 4 bullish TA indicator(s).

  • KALV’s TA Score: 4 bullish, 6 bearish.
  • SYRE’s TA Score: 4 bullish, 5 bearish.
According to our system of comparison, SYRE is a better buy in the short-term than KALV.

Price Growth

KALV (@Biotechnology) experienced а -13.06% price change this week, while SYRE (@Biotechnology) price change was -6.74% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +1.28%. For the same industry, the average monthly price growth was +6.08%, and the average quarterly price growth was +34.58%.

Reported Earning Dates

KALV is expected to report earnings on Dec 04, 2025.

SYRE is expected to report earnings on Nov 06, 2025.

Industries' Descriptions

@Biotechnology (+1.28% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
SYRE($895M) has a higher market cap than KALV($676M). KALV YTD gains are higher at: 57.969 vs. SYRE (-35.180). KALV has higher annual earnings (EBITDA): -173.33M vs. SYRE (-222.15M). SYRE has more cash in the bank: 527M vs. KALV (221M). SYRE has less debt than KALV: SYRE (0) vs KALV (6.31M). KALV (0) and SYRE (0) have equivalent revenues.
KALVSYREKALV / SYRE
Capitalization676M895M76%
EBITDA-173.33M-222.15M78%
Gain YTD57.969-35.180-165%
P/E RatioN/A1.72-
Revenue00-
Total Cash221M527M42%
Total Debt6.31M0-
FUNDAMENTALS RATINGS
KALV vs SYRE: Fundamental Ratings
KALV
SYRE
OUTLOOK RATING
1..100
5610
VALUATION
overvalued / fair valued / undervalued
1..100
79
Overvalued
71
Overvalued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
9998
PRICE GROWTH RATING
1..100
4886
P/E GROWTH RATING
1..100
10080
SEASONALITY SCORE
1..100
34n/a

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

SYRE's Valuation (71) in the Pharmaceuticals Major industry is in the same range as KALV (79) in the Pharmaceuticals Other industry. This means that SYRE’s stock grew similarly to KALV’s over the last 12 months.

SYRE's Profit vs Risk Rating (100) in the Pharmaceuticals Major industry is in the same range as KALV (100) in the Pharmaceuticals Other industry. This means that SYRE’s stock grew similarly to KALV’s over the last 12 months.

SYRE's SMR Rating (98) in the Pharmaceuticals Major industry is in the same range as KALV (99) in the Pharmaceuticals Other industry. This means that SYRE’s stock grew similarly to KALV’s over the last 12 months.

KALV's Price Growth Rating (48) in the Pharmaceuticals Other industry is somewhat better than the same rating for SYRE (86) in the Pharmaceuticals Major industry. This means that KALV’s stock grew somewhat faster than SYRE’s over the last 12 months.

SYRE's P/E Growth Rating (80) in the Pharmaceuticals Major industry is in the same range as KALV (100) in the Pharmaceuticals Other industry. This means that SYRE’s stock grew similarly to KALV’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
KALVSYRE
RSI
ODDS (%)
Bearish Trend 1 day ago
84%
Bullish Trend 2 days ago
82%
Stochastic
ODDS (%)
Bullish Trend 1 day ago
79%
Bullish Trend 2 days ago
84%
Momentum
ODDS (%)
Bearish Trend 1 day ago
86%
Bearish Trend 2 days ago
89%
MACD
ODDS (%)
Bearish Trend 1 day ago
74%
Bearish Trend 2 days ago
90%
TrendWeek
ODDS (%)
Bearish Trend 1 day ago
84%
Bearish Trend 2 days ago
87%
TrendMonth
ODDS (%)
Bullish Trend 1 day ago
82%
Bearish Trend 2 days ago
89%
Advances
ODDS (%)
Bullish Trend 10 days ago
78%
Bullish Trend 13 days ago
85%
Declines
ODDS (%)
Bearish Trend 1 day ago
86%
Bearish Trend 2 days ago
90%
BollingerBands
ODDS (%)
Bearish Trend 1 day ago
83%
Bullish Trend 2 days ago
88%
Aroon
ODDS (%)
Bullish Trend 1 day ago
80%
N/A
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KALV
Daily Signalchanged days ago
Gain/Loss if bought
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SYRE
Daily Signalchanged days ago
Gain/Loss if bought
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KALV and

Correlation & Price change

A.I.dvisor indicates that over the last year, KALV has been loosely correlated with ATXS. These tickers have moved in lockstep 45% of the time. This A.I.-generated data suggests there is some statistical probability that if KALV jumps, then ATXS could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To KALV
1D Price
Change %
KALV100%
-0.89%
ATXS - KALV
45%
Loosely correlated
+1.79%
VRDN - KALV
45%
Loosely correlated
-0.21%
COGT - KALV
42%
Loosely correlated
-1.44%
IRON - KALV
40%
Loosely correlated
+1.15%
KYMR - KALV
39%
Loosely correlated
-1.35%
More

SYRE and

Correlation & Price change

A.I.dvisor indicates that over the last year, SYRE has been loosely correlated with CGON. These tickers have moved in lockstep 60% of the time. This A.I.-generated data suggests there is some statistical probability that if SYRE jumps, then CGON could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SYRE
1D Price
Change %
SYRE100%
+1.82%
CGON - SYRE
60%
Loosely correlated
+5.48%
IDYA - SYRE
59%
Loosely correlated
-1.13%
BEAM - SYRE
57%
Loosely correlated
-1.86%
XNCR - SYRE
57%
Loosely correlated
+7.31%
CRNX - SYRE
56%
Loosely correlated
+0.29%
More