MDGL
Price
$440.89
Change
+$23.46 (+5.62%)
Updated
Sep 18, 04:59 PM (EDT)
Capitalization
9.82B
41 days until earnings call
SYBX
Price
$1.67
Change
-$0.04 (-2.34%)
Updated
Sep 18, 04:59 PM (EDT)
Capitalization
19.54M
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MDGL vs SYBX

Header iconMDGL vs SYBX Comparison
Open Charts MDGL vs SYBXBanner chart's image
Madrigal Pharmaceuticals
Price$440.89
Change+$23.46 (+5.62%)
Volume$3.27K
Capitalization9.82B
Synlogic
Price$1.67
Change-$0.04 (-2.34%)
Volume$200
Capitalization19.54M
MDGL vs SYBX Comparison Chart in %
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MDGL
Daily Signalchanged days ago
Gain/Loss if bought
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SYBX
Daily Signalchanged days ago
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MDGL vs. SYBX commentary
Sep 19, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is MDGL is a Hold and SYBX is a StrongBuy.

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COMPARISON
Comparison
Sep 19, 2025
Stock price -- (MDGL: $440.75 vs. SYBX: $1.67)
Brand notoriety: MDGL and SYBX are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: MDGL: 101% vs. SYBX: 34%
Market capitalization -- MDGL: $9.82B vs. SYBX: $19.54M
MDGL [@Biotechnology] is valued at $9.82B. SYBX’s [@Biotechnology] market capitalization is $19.54M. The market cap for tickers in the [@Biotechnology] industry ranges from $99.25B to $0. The average market capitalization across the [@Biotechnology] industry is $1.89B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

MDGL’s FA Score shows that 1 FA rating(s) are green whileSYBX’s FA Score has 1 green FA rating(s).

  • MDGL’s FA Score: 1 green, 4 red.
  • SYBX’s FA Score: 1 green, 4 red.
According to our system of comparison, MDGL is a better buy in the long-term than SYBX.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

MDGL’s TA Score shows that 4 TA indicator(s) are bullish while SYBX’s TA Score has 3 bullish TA indicator(s).

  • MDGL’s TA Score: 4 bullish, 4 bearish.
  • SYBX’s TA Score: 3 bullish, 4 bearish.
According to our system of comparison, MDGL is a better buy in the short-term than SYBX.

Price Growth

MDGL (@Biotechnology) experienced а +0.30% price change this week, while SYBX (@Biotechnology) price change was +13.61% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +2.03%. For the same industry, the average monthly price growth was +12.13%, and the average quarterly price growth was +38.54%.

Reported Earning Dates

MDGL is expected to report earnings on Oct 30, 2025.

Industries' Descriptions

@Biotechnology (+2.03% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
MDGL($9.82B) has a higher market cap than SYBX($19.5M). MDGL YTD gains are higher at: 42.836 vs. SYBX (19.286). SYBX has higher annual earnings (EBITDA): -11.07M vs. MDGL (-266.74M). MDGL has more cash in the bank: 797M vs. SYBX (17M). SYBX has less debt than MDGL: SYBX (0) vs MDGL (124M). MDGL has higher revenues than SYBX: MDGL (516M) vs SYBX (0).
MDGLSYBXMDGL / SYBX
Capitalization9.82B19.5M50,379%
EBITDA-266.74M-11.07M2,410%
Gain YTD42.83619.286222%
P/E RatioN/A6.36-
Revenue516M0-
Total Cash797M17M4,688%
Total Debt124M0-
FUNDAMENTALS RATINGS
MDGL vs SYBX: Fundamental Ratings
MDGL
SYBX
OUTLOOK RATING
1..100
7715
VALUATION
overvalued / fair valued / undervalued
1..100
65
Fair valued
86
Overvalued
PROFIT vs RISK RATING
1..100
29100
SMR RATING
1..100
9795
PRICE GROWTH RATING
1..100
3840
P/E GROWTH RATING
1..100
10022
SEASONALITY SCORE
1..100
n/a90

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

MDGL's Valuation (65) in the Pharmaceuticals Other industry is in the same range as SYBX (86) in the Biotechnology industry. This means that MDGL’s stock grew similarly to SYBX’s over the last 12 months.

MDGL's Profit vs Risk Rating (29) in the Pharmaceuticals Other industry is significantly better than the same rating for SYBX (100) in the Biotechnology industry. This means that MDGL’s stock grew significantly faster than SYBX’s over the last 12 months.

SYBX's SMR Rating (95) in the Biotechnology industry is in the same range as MDGL (97) in the Pharmaceuticals Other industry. This means that SYBX’s stock grew similarly to MDGL’s over the last 12 months.

MDGL's Price Growth Rating (38) in the Pharmaceuticals Other industry is in the same range as SYBX (40) in the Biotechnology industry. This means that MDGL’s stock grew similarly to SYBX’s over the last 12 months.

SYBX's P/E Growth Rating (22) in the Biotechnology industry is significantly better than the same rating for MDGL (100) in the Pharmaceuticals Other industry. This means that SYBX’s stock grew significantly faster than MDGL’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
MDGLSYBX
RSI
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 2 days ago
90%
Stochastic
ODDS (%)
Bullish Trend 2 days ago
73%
Bearish Trend 2 days ago
90%
Momentum
ODDS (%)
Bearish Trend 2 days ago
82%
Bullish Trend 2 days ago
85%
MACD
ODDS (%)
Bearish Trend 2 days ago
79%
Bullish Trend 2 days ago
86%
TrendWeek
ODDS (%)
Bearish Trend 2 days ago
80%
Bullish Trend 2 days ago
83%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
76%
Bullish Trend 2 days ago
81%
Advances
ODDS (%)
Bullish Trend 11 days ago
78%
Bullish Trend 3 days ago
83%
Declines
ODDS (%)
Bearish Trend 4 days ago
80%
Bearish Trend about 1 month ago
87%
BollingerBands
ODDS (%)
N/A
Bearish Trend 2 days ago
90%
Aroon
ODDS (%)
Bullish Trend 2 days ago
79%
N/A
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MDGL
Daily Signalchanged days ago
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SYBX
Daily Signalchanged days ago
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SYBX and

Correlation & Price change

A.I.dvisor indicates that over the last year, SYBX has been loosely correlated with NEUP. These tickers have moved in lockstep 64% of the time. This A.I.-generated data suggests there is some statistical probability that if SYBX jumps, then NEUP could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SYBX
1D Price
Change %
SYBX100%
-2.34%
NEUP - SYBX
64%
Loosely correlated
-10.54%
BTAI - SYBX
37%
Loosely correlated
+3.47%
SBHMY - SYBX
34%
Loosely correlated
N/A
MDGL - SYBX
31%
Poorly correlated
+5.59%
AUTL - SYBX
29%
Poorly correlated
+6.69%
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