MRK
Price
$113.87
Change
-$1.57 (-1.36%)
Updated
Jun 18 closing price
Capitalization
281.24B
45 days until earnings call
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SNY
Price
$42.38
Change
-$0.12 (-0.28%)
Updated
Jun 18 closing price
Capitalization
101B
40 days until earnings call
Intraday BUY SELL Signals
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MRK vs SNY

MRK vs SNY Comparison Chart in %
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Which Stock Would AI Choose? Merck & Co. (MRK) vs. Sanofi (SNY) Stock Comparison

Key Takeaways

  • MRK has significantly outperformed SNY year-to-date (YTD), with a gain of approximately 12% compared to SNY's 1.5%.
  • MRK's market capitalization stands at around $290 billion, dwarfing SNY's $115 billion, reflecting greater scale.
  • MRK trades at a lower trailing P/E ratio (price-to-earnings) of 16 versus SNY's 20, suggesting relative value.
  • Both stocks benefit from recent regulatory approvals, but MRK shows stronger profit margins at 28% compared to SNY's 17%.
  • In recent market activity, SNY has lagged with a 4.6% decline over the past 30 days amid broader underperformance.

Introduction

Merck & Co. (MRK) and Sanofi (SNY) are leading pharmaceutical giants with diversified portfolios in oncology, immunology, and vaccines. This comparison analyzes their recent performance, financial metrics, and market positioning amid evolving healthcare sector dynamics. Investors seeking exposure to stable dividend payers or growth in biologics, as well as traders monitoring short-term momentum, will find insights into relative strengths, such as MRK's robust oncology franchise versus SNY's immunology focus. With both facing upcoming earnings, understanding these contrasts aids informed stock comparison decisions.

MRK Overview and Recent Performance

Merck & Co. (MRK) is a global healthcare leader specializing in innovative medicines, vaccines, and animal health products. Its blockbuster drug Keytruda drives oncology revenue, complemented by Gardasil for HPV prevention. In recent weeks, MRK shares have traded around $117, with YTD gains of 12% and a 52-week range of $73-$125. Sentiment is mixed ahead of Q1 earnings on April 30, influenced by EU approval for RSV preventive Enflonsia, bolstering its pediatric portfolio, though valuation concerns persist amid year-over-year EPS (earnings per share) pressures. TTM revenue reached $65 billion with a 28% profit margin, supported by 5% quarterly revenue growth.

SNY Overview and Recent Performance

Sanofi (SNY), a French multinational, focuses on vaccines, rare diseases, and consumer healthcare, with Dupixent (co-developed with Regeneron) as a key immunology asset. Shares hover near $48, up modestly YTD at 1.5% but within a 52-week range of $43-$56. Recent market activity shows underperformance, with a 4.6% drop over the past 30 days, ahead of Q1 earnings on April 23. Positive developments include EU approvals for Dupixent in pediatric urticaria, yet broader sentiment reflects challenges in growth consistency. TTM revenue was $47 billion, with a 17% profit margin and 7% quarterly revenue growth.

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Head-to-Head Comparison

Both MRK and SNY operate diversified pharma business models exposed to patent risks and R&D costs, but MRK emphasizes oncology and vaccines while SNY leans into immunology and rare diseases. Growth drivers differ: MRK's Keytruda pipeline extensions contrast SNY's Dupixent expansions. Recent momentum favors MRK with superior YTD returns and stability, versus SNY's relative lag. Risk factors include regulatory hurdles and competition for both, though MRK's higher ROE (return on equity, 37%) signals better capital efficiency than SNY's 7%. Market sentiment tilts toward MRK pre-earnings, highlighting trade-offs in valuation and sector momentum.

Tickeron AI Verdict

Tickeron’s AI models currently favor MRK over SNY, driven by stronger trend consistency, 12% YTD gains, superior margins, and catalysts like Enflonsia approval. SNY offers value via lower forward P/E but trails in relative performance and momentum. This positioning suggests higher probability of near-term outperformance for MRK in volatile healthcare markets.

Disclaimer

The information on this webpage is provided for general informational and educational purposes only and is not intended as investment advice, a recommendation to purchase or sell any security, or an offer or solicitation related to investments. It does not consider your personal financial situation, goals, or risk profile, and all investing carries inherent risks, including the possibility of losing your entire investment. For more details, please review our full disclaimer. Disclaimers and Limitations

VS
MRK vs. SNY commentary
Jun 20, 2026

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is MRK is a Hold and SNY is a Hold.

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COMPARISON
Comparison
Jun 20, 2026
Stock price -- (MRK: $113.87 vs. SNY: $42.38)
Brand notoriety: MRK: Notable vs. SNY: Not notable
Both companies represent the Pharmaceuticals: Major industry
Current volume relative to the 65-day Moving Average: MRK: 288% vs. SNY: 148%
Market capitalization -- MRK: $281.24B vs. SNY: $101B
MRK [@Pharmaceuticals: Major] is valued at $281.24B. SNY’s [@Pharmaceuticals: Major] market capitalization is $101B. The market cap for tickers in the [@Pharmaceuticals: Major] industry ranges from $979.64B to $0. The average market capitalization across the [@Pharmaceuticals: Major] industry is $179.55B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

MRK’s FA Score shows that 3 FA rating(s) are green whileSNY’s FA Score has 1 green FA rating(s).

  • MRK’s FA Score: 3 green, 2 red.
  • SNY’s FA Score: 1 green, 4 red.
According to our system of comparison, MRK is a better buy in the long-term than SNY.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

MRK’s TA Score shows that 4 TA indicator(s) are bullish while SNY’s TA Score has 2 bullish TA indicator(s).

  • MRK’s TA Score: 4 bullish, 6 bearish.
  • SNY’s TA Score: 2 bullish, 8 bearish.
According to our system of comparison, MRK is a better buy in the short-term than SNY.

Price Growth

MRK (@Pharmaceuticals: Major) experienced а -5.03% price change this week, while SNY (@Pharmaceuticals: Major) price change was -3.92% for the same time period.

The average weekly price growth across all stocks in the @Pharmaceuticals: Major industry was +1.18%. For the same industry, the average monthly price growth was +8.31%, and the average quarterly price growth was +2.32%.

Reported Earning Dates

MRK is expected to report earnings on Aug 04, 2026.

SNY is expected to report earnings on Jul 30, 2026.

Industries' Descriptions

@Pharmaceuticals: Major (+1.18% weekly)

The Major Pharmaceuticals industry includes companies that are involved in various processes of creating drugs to treat/prevent diseases. These companies engage in research, testing and manufacturing, as well as the distribution of pharmaceuticals into markets. Johnson & Johnson, Merck & Co., Inc., Pfizer Inc. and Novartis are among the largest companies in this category.

SUMMARIES
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FUNDAMENTALS
Fundamentals
MRK($281B) has a higher market cap than SNY($101B). MRK has higher P/E ratio than SNY: MRK (32.08) vs SNY (18.43). MRK YTD gains are higher at: 9.765 vs. SNY (-7.701). MRK has higher annual earnings (EBITDA): 19.4B vs. SNY (8.52B). SNY has less debt than MRK: SNY (20B) vs MRK (49.1B). MRK has higher revenues than SNY: MRK (65.8B) vs SNY (47.4B).
MRKSNYMRK / SNY
Capitalization281B101B278%
EBITDA19.4B8.52B228%
Gain YTD9.765-7.701-127%
P/E Ratio32.0818.43174%
Revenue65.8B47.4B139%
Total CashN/A5.54B-
Total Debt49.1B20B246%
FUNDAMENTALS RATINGS
MRK vs SNY: Fundamental Ratings
MRK
SNY
OUTLOOK RATING
1..100
1058
VALUATION
overvalued / fair valued / undervalued
1..100
9
Undervalued
3
Undervalued
PROFIT vs RISK RATING
1..100
51100
SMR RATING
1..100
4771
PRICE GROWTH RATING
1..100
3060
P/E GROWTH RATING
1..100
541
SEASONALITY SCORE
1..100
5050

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

SNY's Valuation (3) in the Pharmaceuticals Major industry is in the same range as MRK (9). This means that SNY’s stock grew similarly to MRK’s over the last 12 months.

MRK's Profit vs Risk Rating (51) in the Pharmaceuticals Major industry is somewhat better than the same rating for SNY (100). This means that MRK’s stock grew somewhat faster than SNY’s over the last 12 months.

MRK's SMR Rating (47) in the Pharmaceuticals Major industry is in the same range as SNY (71). This means that MRK’s stock grew similarly to SNY’s over the last 12 months.

MRK's Price Growth Rating (30) in the Pharmaceuticals Major industry is in the same range as SNY (60). This means that MRK’s stock grew similarly to SNY’s over the last 12 months.

MRK's P/E Growth Rating (5) in the Pharmaceuticals Major industry is somewhat better than the same rating for SNY (41). This means that MRK’s stock grew somewhat faster than SNY’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
MRKSNY
RSI
ODDS (%)
Bearish Trend 3 days ago
50%
Bearish Trend 20 days ago
55%
Stochastic
ODDS (%)
Bullish Trend 3 days ago
65%
Bullish Trend 3 days ago
54%
Momentum
ODDS (%)
Bearish Trend 3 days ago
55%
Bearish Trend 3 days ago
47%
MACD
ODDS (%)
Bearish Trend 3 days ago
62%
Bearish Trend 3 days ago
47%
TrendWeek
ODDS (%)
Bearish Trend 3 days ago
49%
Bearish Trend 3 days ago
50%
TrendMonth
ODDS (%)
Bullish Trend 3 days ago
53%
Bearish Trend 3 days ago
43%
Advances
ODDS (%)
Bullish Trend 4 days ago
54%
Bullish Trend 9 days ago
50%
Declines
ODDS (%)
Bearish Trend 6 days ago
51%
Bearish Trend 3 days ago
49%
BollingerBands
ODDS (%)
Bearish Trend 3 days ago
54%
Bearish Trend 3 days ago
56%
Aroon
ODDS (%)
Bullish Trend 3 days ago
64%
Bearish Trend 3 days ago
55%
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MRK
Daily Signal:
Gain/Loss:
SNY
Daily Signal:
Gain/Loss:
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Correlation & Price change

A.I.dvisor indicates that over the last year, SNY has been loosely correlated with NVS. These tickers have moved in lockstep 49% of the time. This A.I.-generated data suggests there is some statistical probability that if SNY jumps, then NVS could also see price increases.

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1Y
5Y
Ticker /
NAME
Correlation
To SNY
1D Price
Change %
SNY100%
-0.28%
NVS - SNY
49%
Loosely correlated
-2.52%
BMY - SNY
47%
Loosely correlated
-2.32%
PFE - SNY
44%
Loosely correlated
-2.74%
MRK - SNY
44%
Loosely correlated
-1.36%
GSK - SNY
41%
Loosely correlated
-2.84%
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