OBIO
Price
$4.65
Change
+$0.42 (+9.93%)
Updated
Nov 19, 04:59 PM (EDT)
Capitalization
263.13M
Intraday BUY SELL Signals
PVLA
Price
$97.00
Change
+$14.06 (+16.95%)
Updated
Nov 19, 04:59 PM (EDT)
Capitalization
1.15B
Intraday BUY SELL Signals
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OBIO vs PVLA

Header iconOBIO vs PVLA Comparison
Open Charts OBIO vs PVLABanner chart's image
Orchestra BioMed Holdings
Price$4.65
Change+$0.42 (+9.93%)
Volume$4.68K
Capitalization263.13M
Palvella Therapeutics
Price$97.00
Change+$14.06 (+16.95%)
Volume$7.09K
Capitalization1.15B
OBIO vs PVLA Comparison Chart in %
OBIO
Daily Signal:
Gain/Loss:
PVLA
Daily Signal:
Gain/Loss:
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VS
OBIO vs. PVLA commentary
Nov 20, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is OBIO is a Hold and PVLA is a Hold.

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COMPARISON
Comparison
Nov 20, 2025
Stock price -- (OBIO: $4.24 vs. PVLA: $82.94)
Brand notoriety: OBIO and PVLA are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: OBIO: 142% vs. PVLA: 127%
Market capitalization -- OBIO: $263.13M vs. PVLA: $1.15B
OBIO [@Biotechnology] is valued at $263.13M. PVLA’s [@Biotechnology] market capitalization is $1.15B. The market cap for tickers in the [@Biotechnology] industry ranges from $106.82B to $0. The average market capitalization across the [@Biotechnology] industry is $2.15B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

OBIO’s FA Score shows that 0 FA rating(s) are green whilePVLA’s FA Score has 1 green FA rating(s).

  • OBIO’s FA Score: 0 green, 5 red.
  • PVLA’s FA Score: 1 green, 4 red.
According to our system of comparison, both OBIO and PVLA are a bad buy in the long-term.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

OBIO’s TA Score shows that 3 TA indicator(s) are bullish while PVLA’s TA Score has 4 bullish TA indicator(s).

  • OBIO’s TA Score: 3 bullish, 5 bearish.
  • PVLA’s TA Score: 4 bullish, 4 bearish.
According to our system of comparison, PVLA is a better buy in the short-term than OBIO.

Price Growth

OBIO (@Biotechnology) experienced а +3.41% price change this week, while PVLA (@Biotechnology) price change was +6.54% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was -2.17%. For the same industry, the average monthly price growth was -5.68%, and the average quarterly price growth was +64.91%.

Industries' Descriptions

@Biotechnology (-2.17% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
PVLA($1.15B) has a higher market cap than OBIO($263M). PVLA YTD gains are higher at: 709.000 vs. OBIO (16.500). PVLA has higher annual earnings (EBITDA): -23.27M vs. OBIO (-70.94M). PVLA has more cash in the bank: 70.4M vs. OBIO (33.9M). OBIO has higher revenues than PVLA: OBIO (2.94M) vs PVLA (0).
OBIOPVLAOBIO / PVLA
Capitalization263M1.15B23%
EBITDA-70.94M-23.27M305%
Gain YTD16.500709.0002%
P/E RatioN/A14.22-
Revenue2.94M0-
Total Cash33.9M70.4M48%
Total Debt16.4MN/A-
FUNDAMENTALS RATINGS
PVLA: Fundamental Ratings
PVLA
OUTLOOK RATING
1..100
77
VALUATION
overvalued / fair valued / undervalued
1..100
77
Overvalued
PROFIT vs RISK RATING
1..100
100
SMR RATING
1..100
96
PRICE GROWTH RATING
1..100
34
P/E GROWTH RATING
1..100
9
SEASONALITY SCORE
1..100
38

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

TECHNICAL ANALYSIS
Technical Analysis
OBIOPVLA
RSI
ODDS (%)
Bearish Trend 2 days ago
48%
Bearish Trend 3 days ago
72%
Stochastic
ODDS (%)
Bearish Trend 2 days ago
71%
Bearish Trend 2 days ago
86%
Momentum
ODDS (%)
Bullish Trend 2 days ago
55%
Bullish Trend 2 days ago
86%
MACD
ODDS (%)
Bearish Trend 2 days ago
50%
Bullish Trend 2 days ago
84%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
52%
Bullish Trend 2 days ago
83%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
51%
Bullish Trend 2 days ago
81%
Advances
ODDS (%)
Bullish Trend 2 days ago
64%
Bullish Trend 14 days ago
86%
Declines
ODDS (%)
Bearish Trend 6 days ago
75%
Bearish Trend 16 days ago
84%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
64%
Bearish Trend 2 days ago
74%
Aroon
ODDS (%)
Bullish Trend 2 days ago
62%
Bullish Trend 2 days ago
85%
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OBIO
Daily Signal:
Gain/Loss:
PVLA
Daily Signal:
Gain/Loss:
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OBIO and

Correlation & Price change

A.I.dvisor indicates that over the last year, OBIO has been loosely correlated with RXRX. These tickers have moved in lockstep 40% of the time. This A.I.-generated data suggests there is some statistical probability that if OBIO jumps, then RXRX could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To OBIO
1D Price
Change %
OBIO100%
+10.17%
RXRX - OBIO
40%
Loosely correlated
-3.12%
XBIT - OBIO
38%
Loosely correlated
-8.30%
RGNX - OBIO
37%
Loosely correlated
-2.84%
BEAM - OBIO
37%
Loosely correlated
-4.24%
OCUL - OBIO
37%
Loosely correlated
+2.81%
More

PVLA and

Correlation & Price change

A.I.dvisor indicates that over the last year, PVLA has been loosely correlated with DRMA. These tickers have moved in lockstep 42% of the time. This A.I.-generated data suggests there is some statistical probability that if PVLA jumps, then DRMA could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To PVLA
1D Price
Change %
PVLA100%
+17.05%
DRMA - PVLA
42%
Loosely correlated
-7.87%
OCUL - PVLA
39%
Loosely correlated
+2.81%
TPST - PVLA
35%
Loosely correlated
-48.59%
OBIO - PVLA
35%
Loosely correlated
+10.17%
LEGN - PVLA
34%
Loosely correlated
-4.72%
More