PROK
Price
$2.71
Change
+$0.18 (+7.11%)
Updated
Sep 18 closing price
Capitalization
368.53M
60 days until earnings call
ZYME
Price
$16.49
Change
+$0.62 (+3.91%)
Updated
Sep 18 closing price
Capitalization
1.25B
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PROK vs ZYME

Header iconPROK vs ZYME Comparison
Open Charts PROK vs ZYMEBanner chart's image
ProKidney
Price$2.71
Change+$0.18 (+7.11%)
Volume$1.3M
Capitalization368.53M
Zymeworks
Price$16.49
Change+$0.62 (+3.91%)
Volume$827.03K
Capitalization1.25B
PROK vs ZYME Comparison Chart in %
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PROK
Daily Signalchanged days ago
Gain/Loss if bought
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ZYME
Daily Signalchanged days ago
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PROK vs. ZYME commentary
Sep 19, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is PROK is a Hold and ZYME is a Hold.

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COMPARISON
Comparison
Sep 19, 2025
Stock price -- (PROK: $2.73 vs. ZYME: $16.49)
Brand notoriety: PROK and ZYME are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: PROK: 35% vs. ZYME: 176%
Market capitalization -- PROK: $368.53M vs. ZYME: $1.25B
PROK [@Biotechnology] is valued at $368.53M. ZYME’s [@Biotechnology] market capitalization is $1.25B. The market cap for tickers in the [@Biotechnology] industry ranges from $99.25B to $0. The average market capitalization across the [@Biotechnology] industry is $1.92B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

PROK’s FA Score shows that 0 FA rating(s) are green whileZYME’s FA Score has 0 green FA rating(s).

  • PROK’s FA Score: 0 green, 5 red.
  • ZYME’s FA Score: 0 green, 5 red.
According to our system of comparison, ZYME is a better buy in the long-term than PROK.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

PROK’s TA Score shows that 4 TA indicator(s) are bullish while ZYME’s TA Score has 6 bullish TA indicator(s).

  • PROK’s TA Score: 4 bullish, 5 bearish.
  • ZYME’s TA Score: 6 bullish, 4 bearish.
According to our system of comparison, ZYME is a better buy in the short-term than PROK.

Price Growth

PROK (@Biotechnology) experienced а -8.39% price change this week, while ZYME (@Biotechnology) price change was +1.04% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +2.03%. For the same industry, the average monthly price growth was +12.13%, and the average quarterly price growth was +38.54%.

Reported Earning Dates

PROK is expected to report earnings on Nov 18, 2025.

Industries' Descriptions

@Biotechnology (+2.03% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
ZYME($1.25B) has a higher market cap than PROK($369M). PROK YTD gains are higher at: 61.538 vs. ZYME (12.637). ZYME has higher annual earnings (EBITDA): -69.77M vs. PROK (-157.52M). PROK (295M) and ZYME (281M) have equal amount of cash in the bank . PROK has less debt than ZYME: PROK (4.42M) vs ZYME (18.7M). ZYME has higher revenues than PROK: ZYME (123M) vs PROK (527K).
PROKZYMEPROK / ZYME
Capitalization369M1.25B30%
EBITDA-157.52M-69.77M226%
Gain YTD61.53812.637487%
P/E RatioN/AN/A-
Revenue527K123M0%
Total Cash295M281M105%
Total Debt4.42M18.7M24%
FUNDAMENTALS RATINGS
ZYME: Fundamental Ratings
ZYME
OUTLOOK RATING
1..100
19
VALUATION
overvalued / fair valued / undervalued
1..100
42
Fair valued
PROFIT vs RISK RATING
1..100
100
SMR RATING
1..100
95
PRICE GROWTH RATING
1..100
42
P/E GROWTH RATING
1..100
61
SEASONALITY SCORE
1..100
50

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

TECHNICAL ANALYSIS
Technical Analysis
PROKZYME
RSI
ODDS (%)
N/A
Bearish Trend 1 day ago
76%
Stochastic
ODDS (%)
Bullish Trend 1 day ago
69%
Bearish Trend 1 day ago
90%
Momentum
ODDS (%)
Bullish Trend 1 day ago
69%
Bullish Trend 1 day ago
74%
MACD
ODDS (%)
Bullish Trend 1 day ago
74%
Bullish Trend 1 day ago
70%
TrendWeek
ODDS (%)
Bearish Trend 1 day ago
69%
Bullish Trend 1 day ago
79%
TrendMonth
ODDS (%)
Bullish Trend 1 day ago
70%
Bullish Trend 1 day ago
81%
Advances
ODDS (%)
Bullish Trend 23 days ago
73%
Bullish Trend 1 day ago
82%
Declines
ODDS (%)
Bearish Trend 5 days ago
81%
Bearish Trend 18 days ago
83%
BollingerBands
ODDS (%)
Bearish Trend 1 day ago
68%
Bearish Trend 1 day ago
77%
Aroon
ODDS (%)
Bearish Trend 1 day ago
76%
Bullish Trend 1 day ago
85%
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PROK
Daily Signalchanged days ago
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ZYME
Daily Signalchanged days ago
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PROK and

Correlation & Price change

A.I.dvisor indicates that over the last year, PROK has been loosely correlated with RLYB. These tickers have moved in lockstep 44% of the time. This A.I.-generated data suggests there is some statistical probability that if PROK jumps, then RLYB could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To PROK
1D Price
Change %
PROK100%
+7.91%
RLYB - PROK
44%
Loosely correlated
+5.54%
NRIX - PROK
39%
Loosely correlated
+4.67%
APGE - PROK
38%
Loosely correlated
+2.07%
KYMR - PROK
37%
Loosely correlated
+6.40%
ZYME - PROK
37%
Loosely correlated
+3.91%
More

ZYME and

Correlation & Price change

A.I.dvisor indicates that over the last year, ZYME has been loosely correlated with NRIX. These tickers have moved in lockstep 50% of the time. This A.I.-generated data suggests there is some statistical probability that if ZYME jumps, then NRIX could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To ZYME
1D Price
Change %
ZYME100%
+3.91%
NRIX - ZYME
50%
Loosely correlated
+4.67%
VRDN - ZYME
48%
Loosely correlated
+5.42%
XNCR - ZYME
47%
Loosely correlated
+8.54%
ELVN - ZYME
47%
Loosely correlated
+4.76%
ABEO - ZYME
47%
Loosely correlated
N/A
More