IOVA
Price
$2.49
Change
+$0.29 (+13.18%)
Updated
Sep 5 closing price
Capitalization
901.02M
61 days until earnings call
OPK
Price
$1.35
Change
-$0.03 (-2.17%)
Updated
Sep 5 closing price
Capitalization
1.07B
60 days until earnings call
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IOVA vs OPK

Header iconIOVA vs OPK Comparison
Open Charts IOVA vs OPKBanner chart's image
Iovance Biotherapeutics
Price$2.49
Change+$0.29 (+13.18%)
Volume$15.23M
Capitalization901.02M
OPKO Health
Price$1.35
Change-$0.03 (-2.17%)
Volume$1.62M
Capitalization1.07B
IOVA vs OPK Comparison Chart in %
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IOVA
Daily Signalchanged days ago
Gain/Loss if bought
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OPK
Daily Signalchanged days ago
Gain/Loss if bought
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A.I.Advisor
published Highlights

Notable companies

The most notable companies in this group are Amgen (NASDAQ:AMGN), Gilead Sciences (NASDAQ:GILD), Regeneron Pharmaceuticals (NASDAQ:REGN), IQVIA Holdings (NYSE:IQV), Biogen (NASDAQ:BIIB), Incyte Corp (NASDAQ:INCY), Illumina (NASDAQ:ILMN), Exelixis (NASDAQ:EXEL), Exact Sciences Corp (NASDAQ:EXAS), Moderna (NASDAQ:MRNA).

Industry description

Few industries pique investor interest like the high-risk, high-reward biotechnology sector. It is not unusual for a biotech company’s stock to soar in value following the development of a successful product...even if it is just as likely that tens of millions of dollars in research will lead to nothing substantial. Biotech companies earn headlines for developing lifesaving and (potentially) massively lucrative treatments for illness, but the industry’s scope extends beyond healthcare to food and agriculture, industrial processing, and more. Any company producing technology that incorporates biological organisms falls within the sector. The search for the next big thing in biotech may come with risk, but investors have reason for optimism. Biotech products like DNA sequencing and gene therapy are experiencing increased demand and decreasing prices, while rising populations around the world mean demand for food and agricultural products resistant to environmental factors. Biotech’s biggest names include multinational corporations like Johnson & Johnson, Amgen, and Roche, who each sport market capitalizations in the hundreds of billions of dollars. With new government rules opening China as a market for new treatments, the biotech sector holds significant growth potential – and corresponding profitability for investors.

Market Cap

The average market capitalization across the biotechnology Theme is 6.91B. The market cap for tickers in the group ranges from 658 to 186.01B. TMO holds the highest valuation in this group at 186.01B. The lowest valued company is MTEM at 658.

High and low price notable news

The average weekly price growth across all stocks in the biotechnology Theme was 4%. For the same Theme, the average monthly price growth was 15%, and the average quarterly price growth was 46%. NBY experienced the highest price growth at 110%, while ADAP experienced the biggest fall at -30%.

Volume

The average weekly volume growth across all stocks in the biotechnology Theme was 8%. For the same stocks of the Theme, the average monthly volume growth was -17% and the average quarterly volume growth was 3%

Fundamental Analysis Ratings

The average fundamental analysis ratings, where 1 is best and 100 is worst, are as follows

Valuation Rating: 59
P/E Growth Rating: 76
Price Growth Rating: 54
SMR Rating: 87
Profit Risk Rating: 89
Seasonality Score: -26 (-100 ... +100)

Market Cap

The average market capitalization across the group is 986.31M. The market cap for tickers in the group ranges from 901.02M to 1.07B. OPK holds the highest valuation in this group at 1.07B. The lowest valued company is IOVA at 901.02M.

High and low price notable news

The average weekly price growth across all stocks in the group was 5%. For the same group, the average monthly price growth was 1%, and the average quarterly price growth was -31%. IOVA experienced the highest price growth at 12%, while OPK experienced the biggest fall at -2%.

Volume

The average weekly volume growth across all stocks in the group was 52%. For the same stocks of the group, the average monthly volume growth was -8% and the average quarterly volume growth was -12%

Fundamental Analysis Ratings

The average fundamental analysis ratings, where 1 is best and 100 is worst, are as follows

Valuation Rating: 40
P/E Growth Rating: 99
Price Growth Rating: 62
SMR Rating: 95
Profit Risk Rating: 100
Seasonality Score: -36 (-100 ... +100)
VS
IOVA vs. OPK commentary
Sep 06, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is IOVA is a StrongBuy and OPK is a Hold.

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COMPARISON
Comparison
Sep 06, 2025
Stock price -- (IOVA: $2.49 vs. OPK: $1.35)
Brand notoriety: IOVA and OPK are both not notable
IOVA represents the Biotechnology, while OPK is part of the Medical Specialties industry
Current volume relative to the 65-day Moving Average: IOVA: 93% vs. OPK: 60%
Market capitalization -- IOVA: $901.02M vs. OPK: $1.07B
IOVA [@Biotechnology] is valued at $901.02M. OPK’s [@Medical Specialties] market capitalization is $1.07B. The market cap for tickers in the [@Biotechnology] industry ranges from $101.56B to $0. The market cap for tickers in the [@Medical Specialties] industry ranges from $3.82T to $0. The average market capitalization across the [@Biotechnology] industry is $1.91B. The average market capitalization across the [@Medical Specialties] industry is $10.68B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

OPK’s FA Score shows that 0 FA rating(s) are green whileIOVA’s FA Score has 1 green FA rating(s).

  • OPK’s FA Score: 0 green, 5 red.
  • IOVA’s FA Score: 1 green, 4 red.
According to our system of comparison, IOVA is a better buy in the long-term than OPK.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

IOVA’s TA Score shows that 4 TA indicator(s) are bullish while OPK’s TA Score has 4 bullish TA indicator(s).

  • IOVA’s TA Score: 4 bullish, 2 bearish.
  • OPK’s TA Score: 4 bullish, 4 bearish.
According to our system of comparison, IOVA is a better buy in the short-term than OPK.

Price Growth

IOVA (@Biotechnology) experienced а +11.66% price change this week, while OPK (@Medical Specialties) price change was -2.17% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +2.52%. For the same industry, the average monthly price growth was +14.48%, and the average quarterly price growth was +31.71%.

The average weekly price growth across all stocks in the @Medical Specialties industry was +1.01%. For the same industry, the average monthly price growth was +8.25%, and the average quarterly price growth was +13.64%.

Reported Earning Dates

IOVA is expected to report earnings on Nov 06, 2025.

OPK is expected to report earnings on Nov 05, 2025.

Industries' Descriptions

@Biotechnology (+2.52% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

@Medical Specialties (+1.01% weekly)

Medical specialties are companies that make equipment used by the health care industry. Equipment manufactured and distributed by these companies include dialysis machines, blood analysis equipment, surgical equipment, dental instruments, and diagnostic tools, among other items. Large companies typically aim to produce and distribute high-quality products across a broad market spectrum. Smaller firms are more likely to specialize in a particular market segment. Due to the industry’s close association with medical treatments, they typically have low sensitivity to macroeconomic fluctuations. Within this industry, Abbott Laboratories, Medtronic Plc and Thermo Fisher Scientific Inc. are some of the companies with multi-billion market capitalizations in the U.S. stock markets.

SUMMARIES
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FUNDAMENTALS
Fundamentals
OPK($1.07B) has a higher market cap than IOVA($901M). OPK YTD gains are higher at: -8.163 vs. IOVA (-66.351). OPK has higher annual earnings (EBITDA): 59.6M vs. IOVA (-364.8M). IOVA has more cash in the bank: 301M vs. OPK (272M). IOVA has less debt than OPK: IOVA (53.2M) vs OPK (396M). OPK has higher revenues than IOVA: OPK (664M) vs IOVA (242M).
IOVAOPKIOVA / OPK
Capitalization901M1.07B84%
EBITDA-364.8M59.6M-612%
Gain YTD-66.351-8.163813%
P/E RatioN/AN/A-
Revenue242M664M36%
Total Cash301M272M111%
Total Debt53.2M396M13%
FUNDAMENTALS RATINGS
OPK vs IOVA: Fundamental Ratings
OPK
IOVA
OUTLOOK RATING
1..100
2467
VALUATION
overvalued / fair valued / undervalued
1..100
56
Fair valued
24
Undervalued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
9497
PRICE GROWTH RATING
1..100
6065
P/E GROWTH RATING
1..100
98100
SEASONALITY SCORE
1..100
4924

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

IOVA's Valuation (24) in the Biotechnology industry is in the same range as OPK (56). This means that IOVA’s stock grew similarly to OPK’s over the last 12 months.

IOVA's Profit vs Risk Rating (100) in the Biotechnology industry is in the same range as OPK (100). This means that IOVA’s stock grew similarly to OPK’s over the last 12 months.

OPK's SMR Rating (94) in the Biotechnology industry is in the same range as IOVA (97). This means that OPK’s stock grew similarly to IOVA’s over the last 12 months.

OPK's Price Growth Rating (60) in the Biotechnology industry is in the same range as IOVA (65). This means that OPK’s stock grew similarly to IOVA’s over the last 12 months.

OPK's P/E Growth Rating (98) in the Biotechnology industry is in the same range as IOVA (100). This means that OPK’s stock grew similarly to IOVA’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
IOVAOPK
RSI
ODDS (%)
N/A
N/A
Stochastic
ODDS (%)
Bullish Trend 2 days ago
82%
Bearish Trend 2 days ago
83%
Momentum
ODDS (%)
Bearish Trend 2 days ago
82%
Bearish Trend 2 days ago
86%
MACD
ODDS (%)
N/A
Bearish Trend 2 days ago
75%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
80%
Bearish Trend 2 days ago
80%
TrendMonth
ODDS (%)
Bearish Trend 2 days ago
88%
Bullish Trend 2 days ago
73%
Advances
ODDS (%)
Bullish Trend 16 days ago
79%
Bullish Trend 20 days ago
75%
Declines
ODDS (%)
Bearish Trend 10 days ago
89%
Bearish Trend 5 days ago
80%
BollingerBands
ODDS (%)
Bullish Trend 2 days ago
84%
N/A
Aroon
ODDS (%)
N/A
Bullish Trend 2 days ago
76%
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IOVA
Daily Signalchanged days ago
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OPK
Daily Signalchanged days ago
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IOVA and Stocks

Correlation & Price change

A.I.dvisor indicates that over the last year, IOVA has been loosely correlated with PLX. These tickers have moved in lockstep 46% of the time. This A.I.-generated data suggests there is some statistical probability that if IOVA jumps, then PLX could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To IOVA
1D Price
Change %
IOVA100%
+13.18%
PLX - IOVA
46%
Loosely correlated
-3.14%
VCYT - IOVA
43%
Loosely correlated
+2.89%
ROIV - IOVA
43%
Loosely correlated
+2.78%
IDYA - IOVA
40%
Loosely correlated
+5.15%
XNCR - IOVA
39%
Loosely correlated
+2.15%
More

OPK and Stocks

Correlation & Price change

A.I.dvisor indicates that over the last year, OPK has been loosely correlated with ICUI. These tickers have moved in lockstep 41% of the time. This A.I.-generated data suggests there is some statistical probability that if OPK jumps, then ICUI could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To OPK
1D Price
Change %
OPK100%
-2.17%
ICUI - OPK
41%
Loosely correlated
+4.47%
CLPT - OPK
39%
Loosely correlated
-0.27%
UTMD - OPK
36%
Loosely correlated
+1.04%
XAIR - OPK
35%
Loosely correlated
+1.84%
NOTV - OPK
34%
Loosely correlated
+2.50%
More