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SEPN
Stock ticker: NASDAQ
AS OF
Aug 21 closing price
Price
$11.70
Change
+$0.61 (+5.50%)
Capitalization
521.65M

SEPN Septerna Inc Forecast, Technical & Fundamental Analysis

Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform... Show more

SEPN
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A.I.Advisor
a Summary for SEPN with price predictions
Aug 21, 2025

SEPN sees MACD Histogram crosses below signal line

SEPN saw its Moving Average Convergence Divergence Histogram (MACD) turn negative on July 30, 2025. This is a bearish signal that suggests the stock could decline going forward. Tickeron's A.I.dvisor looked at 2 instances where the indicator turned negative. In of the 2 cases the stock moved lower in the days that followed. This puts the odds of a downward move at .

Price Prediction Chart

Technical Analysis (Indicators)

Bearish Trend Analysis

The 10-day RSI Indicator for SEPN moved out of overbought territory on July 29, 2025. This could be a bearish sign for the stock. Traders may want to consider selling the stock or buying put options. Tickeron's A.I.dvisor looked at 4 similar instances where the indicator moved out of overbought territory. In of the 4 cases, the stock moved lower in the following days. This puts the odds of a move lower at .

The 10-day moving average for SEPN crossed bearishly below the 50-day moving average on August 20, 2025. This indicates that the trend has shifted lower and could be considered a sell signal. In of 1 past instances when the 10-day crossed below the 50-day, the stock continued to move higher over the following month. The odds of a continued downward trend are .

Following a 3-day decline, the stock is projected to fall further. Considering past instances where SEPN declined for three days, the price rose further in of 62 cases within the following month. The odds of a continued downward trend are .

Bullish Trend Analysis

The Stochastic Oscillator suggests the stock price trend may be in a reversal from a downward trend to an upward trend. of 10 cases where SEPN's Stochastic Oscillator exited the oversold zone resulted in an increase in price. Tickeron's analysis proposes that the odds of a continued upward trend are .

The Momentum Indicator moved above the 0 level on August 21, 2025. You may want to consider a long position or call options on SEPN as a result. In of 14 past instances where the momentum indicator moved above 0, the stock continued to climb. The odds of a continued upward trend are .

SEPN moved above its 50-day moving average on August 21, 2025 date and that indicates a change from a downward trend to an upward trend.

Following a 3-day Advance, the price is estimated to grow further. Considering data from situations where SEPN advanced for three days, in of 37 cases, the price rose further within the following month. The odds of a continued upward trend are .

SEPN may jump back above the lower band and head toward the middle band. Traders may consider buying the stock or exploring call options.

The Aroon Indicator entered an Uptrend today. In of 21 cases where SEPN Aroon's Indicator entered an Uptrend, the price rose further within the following month. The odds of a continued Uptrend are .

Fundamental Analysis (Ratings)

The Tickeron Price Growth Rating for this company is (best 1 - 100 worst), indicating steady price growth. SEPN’s price grows at a higher rate over the last 12 months as compared to S&P 500 index constituents.

The Tickeron Valuation Rating of (best 1 - 100 worst) indicates that the company is slightly overvalued in the industry. This rating compares market capitalization estimated by our proprietary formula with the current market capitalization. This rating is based on the following metrics, as compared to industry averages: P/B Ratio (1.382) is normal, around the industry mean (19.773). P/E Ratio (0.000) is within average values for comparable stocks, (54.197). Projected Growth (PEG Ratio) (0.000) is also within normal values, averaging (2.633). Dividend Yield (0.000) settles around the average of (0.043) among similar stocks. P/S Ratio (714.286) is also within normal values, averaging (300.579).

The Tickeron PE Growth Rating for this company is (best 1 - 100 worst), pointing to worse than average earnings growth. The PE Growth rating is based on a comparative analysis of stock PE ratio increase over the last 12 months compared against S&P 500 index constituents.

The Tickeron SMR rating for this company is (best 1 - 100 worst), indicating weak sales and an unprofitable business model. SMR (Sales, Margin, Return on Equity) rating is based on comparative analysis of weighted Sales, Income Margin and Return on Equity values compared against S&P 500 index constituents. The weighted SMR value is a proprietary formula developed by Tickeron and represents an overall profitability measure for a stock.

The Tickeron Profit vs. Risk Rating rating for this company is (best 1 - 100 worst), indicating that the returns do not compensate for the risks. SEPN’s unstable profits reported over time resulted in significant Drawdowns within these last five years. A stable profit reduces stock drawdown and volatility. The average Profit vs. Risk Rating rating for the industry is 95, placing this stock worse than average.

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SEPN
Daily Signalchanged days ago
Gain/Loss if bought
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A.I. Advisor
published Earnings

SEPN is expected to report earnings to rise 16.07% to -64 cents per share on November 19

Septerna Inc SEPN Stock Earnings Reports
Q3'25
Est.
$-0.65
Q2'25
Beat
by $0.07
Q1'25
Beat
by $0.05
The last earnings report on August 11 showed earnings per share of -56 cents, beating the estimate of -62 cents. With 142.83K shares outstanding, the current market capitalization sits at 521.65M.
A.I. Advisor
published General Information

General Information

Industry Biotechnology

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