AMGN
Price
$349.58
Change
+$3.98 (+1.15%)
Updated
Jun 5 closing price
Capitalization
188.67B
53 days until earnings call
Intraday BUY SELL Signals
PFE
Price
$26.04
Change
+$0.35 (+1.36%)
Updated
Jun 5 closing price
Capitalization
148.41B
58 days until earnings call
Intraday BUY SELL Signals
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AMGN vs PFE

Header iconAMGN vs PFE Comparison
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AMGN vs PFE Comparison Chart in %
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Which Stock Would AI Choose? Amgen (AMGN) vs. Pfizer (PFE) Stock Comparison

Key Takeaways

  • Amgen (AMGN) delivered Q1 2026 earnings that beat expectations, with revenue of $8.62 billion and adjusted EPS (earnings per share) of $5.15, offsetting patent losses through growth drivers.
  • Pfizer (PFE) offers a higher dividend yield of 6.53%, compared to AMGN's 3.06%, attracting income-oriented investors.
  • Year-to-date (YTD), PFE has gained approximately 7%, outperforming AMGN's roughly 1% return, amid recent market volatility.
  • Both exhibit low beta values—AMGN at 0.44 and PFE at 0.31—indicating defensive positioning with reduced market sensitivity.
  • Analyst average price targets point to potential upside: $353 for AMGN (from ~$330) and $29 for PFE (from ~$26).
  • AMGN's forward PE ratio (price-to-earnings) of 14.75 suggests growth expectations, while PFE's 8.98 reflects value amid pipeline catalysts.

Introduction

Amgen (AMGN) and Pfizer (PFE), two pillars of the pharmaceutical industry, offer distinct profiles for investors navigating healthcare sector dynamics. AMGN emphasizes biotechnology innovation in areas like oncology and emerging obesity therapies, while PFE provides broad exposure to vaccines, oncology, and established drugs. This comparison is particularly relevant for traders seeking relative performance insights amid recent earnings cycles and dividend announcements, and for long-term investors balancing growth potential against income stability in a market favoring defensive plays. Key metrics reveal trade-offs in valuation, momentum, and risk, aiding informed positioning.

AMGN Overview and Recent Performance

Amgen Inc. is a biotechnology leader focused on human therapeutics, with key franchises in oncology, inflammation, and cardiovascular diseases, alongside pipeline advancements in obesity. In recent weeks, AMGN shares traded around $330, reflecting a market capitalization (market cap) of approximately $178 billion. The stock experienced a post-earnings pullback despite Q1 2026 results exceeding forecasts—revenue rose to $8.62 billion, adjusted EPS hit $5.15, and 16 products posted double-digit growth. Sentiment has been influenced by robust pipeline updates, including obesity drug MariTide progress and a dividend hike to $2.52 (ex-date May 15, 2026), though tax risks and competition tempered gains. YTD performance stands at about 1%, with a trailing PE ratio of 22.94 and beta of 0.44 signaling relative stability.

PFE Overview and Recent Performance

Pfizer Inc. operates as a global biopharmaceutical firm with diverse offerings in oncology, immunology, vaccines, and rare diseases. Recently, PFE shares hovered near $26, with a market cap of about $150 billion. Performance has shown resilience, with YTD gains around 7% and a one-month decline of roughly 5%, amid broader sector pressures. Key influences include anticipation of pipeline catalysts like FDA approvals for partnered drugs and a sturdy dividend of $0.43 (yield 6.53%, ex-date May 8, 2026), though patent expirations pose headwinds. Trading volume remains elevated, beta at 0.31 underscores low volatility, and trailing PE ratio of 19.36 reflects value positioning relative to peers.

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Head-to-Head Comparison

Both AMGN and PFE anchor the pharma sector but diverge in business models: AMGN's biotech emphasis drives innovation in high-growth areas like obesity and oncology, contrasting PFE's diversified portfolio bolstered by vaccines and M&A (mergers and acquisitions). Growth drivers favor AMGN's pipeline momentum, including MariTide, over PFE's post-COVID stabilization and combo therapies. Recent momentum shows PFE's superior YTD edge, yet AMGN's earnings beat signals rebound potential. Risk factors include patent cliffs for both, with PFE more exposed; sector exposure is shared in healthcare defensives. Market sentiment tilts positive for AMGN's execution amid analysts' upside targets, while PFE appeals via yield and value metrics like lower forward PE.

Tickeron AI Verdict

Tickeron's AI currently favors AMGN over PFE, based on stronger trend consistency from recent earnings outperformance, pipeline catalysts in obesity, and relative stability despite volatility. AMGN's growth offsetting patent risks positions it probabilistically ahead in the near term, though PFE's yield and valuation offer compelling counterbalance for conservative strategies.

Disclaimer

The information on this webpage is provided for general informational and educational purposes only and is not intended as investment advice, a recommendation to purchase or sell any security, or an offer or solicitation related to investments. It does not consider your personal financial situation, goals, or risk profile, and all investing carries inherent risks, including the possibility of losing your entire investment. For more details, please review our full disclaimer. Disclaimers and Limitations

VS
AMGN vs. PFE commentary
Jun 07, 2026

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is AMGN is a StrongBuy and PFE is a Buy.

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COMPARISON
Comparison
Jun 07, 2026
Stock price -- (AMGN: $349.58 vs. PFE: $26.04)
Brand notoriety: AMGN and PFE are both notable
Both companies represent the Pharmaceuticals: Major industry
Current volume relative to the 65-day Moving Average: AMGN: 137% vs. PFE: 94%
Market capitalization -- AMGN: $188.67B vs. PFE: $148.41B
AMGN [@Pharmaceuticals: Major] is valued at $188.67B. PFE’s [@Pharmaceuticals: Major] market capitalization is $148.41B. The market cap for tickers in the [@Pharmaceuticals: Major] industry ranges from $1.01T to $0. The average market capitalization across the [@Pharmaceuticals: Major] industry is $185.2B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

AMGN’s FA Score shows that 3 FA rating(s) are green whilePFE’s FA Score has 2 green FA rating(s).

  • AMGN’s FA Score: 3 green, 2 red.
  • PFE’s FA Score: 2 green, 3 red.
According to our system of comparison, AMGN is a better buy in the long-term than PFE.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

AMGN’s TA Score shows that 5 TA indicator(s) are bullish while PFE’s TA Score has 5 bullish TA indicator(s).

  • AMGN’s TA Score: 5 bullish, 4 bearish.
  • PFE’s TA Score: 5 bullish, 2 bearish.
According to our system of comparison, PFE is a better buy in the short-term than AMGN.

Price Growth

AMGN (@Pharmaceuticals: Major) experienced а +3.80% price change this week, while PFE (@Pharmaceuticals: Major) price change was -0.53% for the same time period.

The average weekly price growth across all stocks in the @Pharmaceuticals: Major industry was +0.22%. For the same industry, the average monthly price growth was +2.11%, and the average quarterly price growth was +2.84%.

Reported Earning Dates

AMGN is expected to report earnings on Jul 30, 2026.

PFE is expected to report earnings on Aug 04, 2026.

Industries' Descriptions

@Pharmaceuticals: Major (+0.22% weekly)

The Major Pharmaceuticals industry includes companies that are involved in various processes of creating drugs to treat/prevent diseases. These companies engage in research, testing and manufacturing, as well as the distribution of pharmaceuticals into markets. Johnson & Johnson, Merck & Co., Inc., Pfizer Inc. and Novartis are among the largest companies in this category.

SUMMARIES
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FUNDAMENTALS
Fundamentals
AMGN($189B) has a higher market cap than PFE($148B). AMGN has higher P/E ratio than PFE: AMGN (24.33) vs PFE (19.88). AMGN (8.356) and PFE (8.085) have similar YTD gains . PFE (17.2B) and AMGN (16.7B) have comparable annual earnings (EBITDA) . PFE has more cash in the bank: 13.1B vs. AMGN (12B). AMGN has less debt than PFE: AMGN (57.3B) vs PFE (63.7B). PFE has higher revenues than AMGN: PFE (63.3B) vs AMGN (37.2B).
AMGNPFEAMGN / PFE
Capitalization189B148B128%
EBITDA16.7B17.2B97%
Gain YTD8.3568.085103%
P/E Ratio24.3319.88122%
Revenue37.2B63.3B59%
Total Cash12B13.1B92%
Total Debt57.3B63.7B90%
FUNDAMENTALS RATINGS
AMGN vs PFE: Fundamental Ratings
AMGN
PFE
OUTLOOK RATING
1..100
4289
VALUATION
overvalued / fair valued / undervalued
1..100
6
Undervalued
5
Undervalued
PROFIT vs RISK RATING
1..100
24100
SMR RATING
1..100
1278
PRICE GROWTH RATING
1..100
4951
P/E GROWTH RATING
1..100
6033
SEASONALITY SCORE
1..100
65n/a

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

PFE's Valuation (5) in the Pharmaceuticals Major industry is in the same range as AMGN (6) in the Biotechnology industry. This means that PFE’s stock grew similarly to AMGN’s over the last 12 months.

AMGN's Profit vs Risk Rating (24) in the Biotechnology industry is significantly better than the same rating for PFE (100) in the Pharmaceuticals Major industry. This means that AMGN’s stock grew significantly faster than PFE’s over the last 12 months.

AMGN's SMR Rating (12) in the Biotechnology industry is significantly better than the same rating for PFE (78) in the Pharmaceuticals Major industry. This means that AMGN’s stock grew significantly faster than PFE’s over the last 12 months.

AMGN's Price Growth Rating (49) in the Biotechnology industry is in the same range as PFE (51) in the Pharmaceuticals Major industry. This means that AMGN’s stock grew similarly to PFE’s over the last 12 months.

PFE's P/E Growth Rating (33) in the Pharmaceuticals Major industry is in the same range as AMGN (60) in the Biotechnology industry. This means that PFE’s stock grew similarly to AMGN’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
AMGNPFE
RSI
ODDS (%)
Bullish Trend 2 days ago
68%
N/A
Stochastic
ODDS (%)
Bearish Trend 2 days ago
40%
Bullish Trend 2 days ago
65%
Momentum
ODDS (%)
Bullish Trend 2 days ago
54%
Bullish Trend 2 days ago
56%
MACD
ODDS (%)
Bullish Trend 2 days ago
56%
Bullish Trend 2 days ago
49%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
58%
Bearish Trend 2 days ago
58%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
56%
Bullish Trend 2 days ago
50%
Advances
ODDS (%)
Bullish Trend 2 days ago
56%
Bullish Trend 2 days ago
56%
Declines
ODDS (%)
Bearish Trend 5 days ago
52%
Bearish Trend 4 days ago
58%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
51%
Bullish Trend 2 days ago
59%
Aroon
ODDS (%)
Bearish Trend 2 days ago
54%
Bearish Trend 2 days ago
59%
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