AXSM
Price
$121.75
Change
-$0.11 (-0.09%)
Updated
Aug 28 closing price
Capitalization
6.08B
73 days until earnings call
IONS
Price
$42.62
Change
-$0.13 (-0.30%)
Updated
Aug 28 closing price
Capitalization
6.79B
62 days until earnings call
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AXSM vs IONS

Header iconAXSM vs IONS Comparison
Open Charts AXSM vs IONSBanner chart's image
Axsome Therapeutics
Price$121.75
Change-$0.11 (-0.09%)
Volume$369.67K
Capitalization6.08B
Ionis Pharmaceuticals
Price$42.62
Change-$0.13 (-0.30%)
Volume$1.1M
Capitalization6.79B
AXSM vs IONS Comparison Chart in %
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AXSM
Daily Signalchanged days ago
Gain/Loss if bought
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IONS
Daily Signalchanged days ago
Gain/Loss if bought
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AXSM vs. IONS commentary
Aug 29, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is AXSM is a Buy and IONS is a Buy.

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COMPARISON
Comparison
Aug 29, 2025
Stock price -- (AXSM: $121.75 vs. IONS: $42.62)
Brand notoriety: AXSM and IONS are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: AXSM: 58% vs. IONS: 54%
Market capitalization -- AXSM: $6.08B vs. IONS: $6.79B
AXSM [@Biotechnology] is valued at $6.08B. IONS’s [@Biotechnology] market capitalization is $6.79B. The market cap for tickers in the [@Biotechnology] industry ranges from $100.52B to $0. The average market capitalization across the [@Biotechnology] industry is $1.84B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

AXSM’s FA Score shows that 0 FA rating(s) are green whileIONS’s FA Score has 0 green FA rating(s).

  • AXSM’s FA Score: 0 green, 5 red.
  • IONS’s FA Score: 0 green, 5 red.
According to our system of comparison, AXSM is a better buy in the long-term than IONS.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

AXSM’s TA Score shows that 5 TA indicator(s) are bullish while IONS’s TA Score has 3 bullish TA indicator(s).

  • AXSM’s TA Score: 5 bullish, 5 bearish.
  • IONS’s TA Score: 3 bullish, 4 bearish.
According to our system of comparison, AXSM is a better buy in the short-term than IONS.

Price Growth

AXSM (@Biotechnology) experienced а +3.94% price change this week, while IONS (@Biotechnology) price change was -1.42% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +2.11%. For the same industry, the average monthly price growth was +20.33%, and the average quarterly price growth was +29.99%.

Reported Earning Dates

AXSM is expected to report earnings on Nov 10, 2025.

IONS is expected to report earnings on Oct 30, 2025.

Industries' Descriptions

@Biotechnology (+2.11% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
IONS($6.79B) has a higher market cap than AXSM($6.08B). AXSM YTD gains are higher at: 43.896 vs. IONS (21.911). IONS has higher annual earnings (EBITDA): -170.69M vs. AXSM (-230.81M). IONS has more cash in the bank: 2.29B vs. AXSM (303M). AXSM has less debt than IONS: AXSM (217M) vs IONS (1.42B). IONS has higher revenues than AXSM: IONS (944M) vs AXSM (495M).
AXSMIONSAXSM / IONS
Capitalization6.08B6.79B89%
EBITDA-230.81M-170.69M135%
Gain YTD43.89621.911200%
P/E RatioN/AN/A-
Revenue495M944M52%
Total Cash303M2.29B13%
Total Debt217M1.42B15%
FUNDAMENTALS RATINGS
AXSM vs IONS: Fundamental Ratings
AXSM
IONS
OUTLOOK RATING
1..100
2877
VALUATION
overvalued / fair valued / undervalued
1..100
90
Overvalued
96
Overvalued
PROFIT vs RISK RATING
1..100
57100
SMR RATING
1..100
100100
PRICE GROWTH RATING
1..100
4346
P/E GROWTH RATING
1..100
100100
SEASONALITY SCORE
1..100
5050

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

AXSM's Valuation (90) in the Pharmaceuticals Other industry is in the same range as IONS (96) in the Biotechnology industry. This means that AXSM’s stock grew similarly to IONS’s over the last 12 months.

AXSM's Profit vs Risk Rating (57) in the Pharmaceuticals Other industry is somewhat better than the same rating for IONS (100) in the Biotechnology industry. This means that AXSM’s stock grew somewhat faster than IONS’s over the last 12 months.

AXSM's SMR Rating (100) in the Pharmaceuticals Other industry is in the same range as IONS (100) in the Biotechnology industry. This means that AXSM’s stock grew similarly to IONS’s over the last 12 months.

AXSM's Price Growth Rating (43) in the Pharmaceuticals Other industry is in the same range as IONS (46) in the Biotechnology industry. This means that AXSM’s stock grew similarly to IONS’s over the last 12 months.

AXSM's P/E Growth Rating (100) in the Pharmaceuticals Other industry is in the same range as IONS (100) in the Biotechnology industry. This means that AXSM’s stock grew similarly to IONS’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
AXSMIONS
RSI
ODDS (%)
Bearish Trend 1 day ago
82%
N/A
Stochastic
ODDS (%)
Bearish Trend 1 day ago
74%
Bullish Trend 1 day ago
68%
Momentum
ODDS (%)
Bullish Trend 1 day ago
87%
Bearish Trend 1 day ago
72%
MACD
ODDS (%)
Bullish Trend 1 day ago
83%
Bearish Trend 1 day ago
65%
TrendWeek
ODDS (%)
Bullish Trend 1 day ago
77%
Bearish Trend 1 day ago
68%
TrendMonth
ODDS (%)
Bullish Trend 1 day ago
78%
Bullish Trend 1 day ago
72%
Advances
ODDS (%)
Bullish Trend 2 days ago
78%
Bullish Trend 2 days ago
64%
Declines
ODDS (%)
Bearish Trend 23 days ago
81%
Bearish Trend 4 days ago
68%
BollingerBands
ODDS (%)
Bearish Trend 1 day ago
83%
Bearish Trend 1 day ago
72%
Aroon
ODDS (%)
Bearish Trend 1 day ago
72%
Bullish Trend 1 day ago
68%
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AXSM
Daily Signalchanged days ago
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IONS
Daily Signalchanged days ago
Gain/Loss if bought
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AXSM and

Correlation & Price change

A.I.dvisor indicates that over the last year, AXSM has been loosely correlated with CRNX. These tickers have moved in lockstep 40% of the time. This A.I.-generated data suggests there is some statistical probability that if AXSM jumps, then CRNX could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To AXSM
1D Price
Change %
AXSM100%
-0.09%
CRNX - AXSM
40%
Loosely correlated
+0.82%
ALNY - AXSM
37%
Loosely correlated
-0.41%
XENE - AXSM
36%
Loosely correlated
-0.69%
IONS - AXSM
36%
Loosely correlated
-0.30%
VANI - AXSM
36%
Loosely correlated
-3.28%
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