CSTL
Price
$37.88
Change
+$2.16 (+6.05%)
Updated
Nov 21 closing price
Capitalization
1.11B
102 days until earnings call
Intraday BUY SELL Signals
RGEN
Price
$162.51
Change
+$8.15 (+5.28%)
Updated
Nov 21 closing price
Capitalization
9.15B
95 days until earnings call
Intraday BUY SELL Signals
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CSTL vs RGEN

Header iconCSTL vs RGEN Comparison
Open Charts CSTL vs RGENBanner chart's image
Castle Biosciences
Price$37.88
Change+$2.16 (+6.05%)
Volume$727.79K
Capitalization1.11B
Repligen
Price$162.51
Change+$8.15 (+5.28%)
Volume$892.07K
Capitalization9.15B
CSTL vs RGEN Comparison Chart in %
CSTL
Daily Signal:
Gain/Loss:
RGEN
Daily Signal:
Gain/Loss:
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VS
CSTL vs. RGEN commentary
Nov 22, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is CSTL is a Hold and RGEN is a Hold.

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COMPARISON
Comparison
Nov 22, 2025
Stock price -- (CSTL: $37.91 vs. RGEN: $162.60)
Brand notoriety: CSTL and RGEN are both not notable
CSTL represents the Medical Specialties, while RGEN is part of the Pharmaceuticals: Other industry
Current volume relative to the 65-day Moving Average: CSTL: 188% vs. RGEN: 89%
Market capitalization -- CSTL: $1.11B vs. RGEN: $9.15B
CSTL [@Medical Specialties] is valued at $1.11B. RGEN’s [@Pharmaceuticals: Other] market capitalization is $9.15B. The market cap for tickers in the [@Medical Specialties] industry ranges from $3.82T to $0. The market cap for tickers in the [@Pharmaceuticals: Other] industry ranges from $199.09B to $0. The average market capitalization across the [@Medical Specialties] industry is $12.32B. The average market capitalization across the [@Pharmaceuticals: Other] industry is $11.75B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

CSTL’s FA Score shows that 0 FA rating(s) are green whileRGEN’s FA Score has 1 green FA rating(s).

  • CSTL’s FA Score: 0 green, 5 red.
  • RGEN’s FA Score: 1 green, 4 red.
According to our system of comparison, RGEN is a better buy in the long-term than CSTL.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

CSTL’s TA Score shows that 5 TA indicator(s) are bullish while RGEN’s TA Score has 5 bullish TA indicator(s).

  • CSTL’s TA Score: 5 bullish, 4 bearish.
  • RGEN’s TA Score: 5 bullish, 4 bearish.
According to our system of comparison, both CSTL and RGEN are a good buy in the short-term.

Price Growth

CSTL (@Medical Specialties) experienced а +13.33% price change this week, while RGEN (@Pharmaceuticals: Other) price change was +6.71% for the same time period.

The average weekly price growth across all stocks in the @Medical Specialties industry was +0.55%. For the same industry, the average monthly price growth was +0.85%, and the average quarterly price growth was +30.79%.

The average weekly price growth across all stocks in the @Pharmaceuticals: Other industry was -0.94%. For the same industry, the average monthly price growth was +2.64%, and the average quarterly price growth was +10.24%.

Reported Earning Dates

CSTL is expected to report earnings on Mar 04, 2026.

RGEN is expected to report earnings on Feb 25, 2026.

Industries' Descriptions

@Medical Specialties (+0.55% weekly)

Medical specialties are companies that make equipment used by the health care industry. Equipment manufactured and distributed by these companies include dialysis machines, blood analysis equipment, surgical equipment, dental instruments, and diagnostic tools, among other items. Large companies typically aim to produce and distribute high-quality products across a broad market spectrum. Smaller firms are more likely to specialize in a particular market segment. Due to the industry’s close association with medical treatments, they typically have low sensitivity to macroeconomic fluctuations. Within this industry, Abbott Laboratories, Medtronic Plc and Thermo Fisher Scientific Inc. are some of the companies with multi-billion market capitalizations in the U.S. stock markets.

@Pharmaceuticals: Other (-0.94% weekly)

Pharmaceuticals (Other) comprise companies that are involved in the discovery, development or manufacturing of therapeutic and preventative medicines. They often collaborate with or acquire other pharmaceutical/healthcare firms. Examples of companies in this segment include Bausch Health Companies Inc., Icon Plc and Perrigo Company Plc.

SUMMARIES
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FUNDAMENTALS
Fundamentals
RGEN($9.15B) has a higher market cap than CSTL($1.11B). RGEN has higher P/E ratio than CSTL: RGEN (8130.00) vs CSTL (30.24). CSTL YTD gains are higher at: 42.251 vs. RGEN (12.964). RGEN has higher annual earnings (EBITDA): 99.5M vs. CSTL (32.6M). RGEN has more cash in the bank: 709M vs. CSTL (276M). CSTL has less debt than RGEN: CSTL (37.4M) vs RGEN (686M). RGEN has higher revenues than CSTL: RGEN (674M) vs CSTL (346M).
CSTLRGENCSTL / RGEN
Capitalization1.11B9.15B12%
EBITDA32.6M99.5M33%
Gain YTD42.25112.964326%
P/E Ratio30.248130.000%
Revenue346M674M51%
Total Cash276M709M39%
Total Debt37.4M686M5%
FUNDAMENTALS RATINGS
CSTL vs RGEN: Fundamental Ratings
CSTL
RGEN
OUTLOOK RATING
1..100
9013
VALUATION
overvalued / fair valued / undervalued
1..100
57
Fair valued
97
Overvalued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
8786
PRICE GROWTH RATING
1..100
3544
P/E GROWTH RATING
1..100
9932
SEASONALITY SCORE
1..100
n/a50

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

CSTL's Valuation (57) in the null industry is somewhat better than the same rating for RGEN (97) in the Biotechnology industry. This means that CSTL’s stock grew somewhat faster than RGEN’s over the last 12 months.

CSTL's Profit vs Risk Rating (100) in the null industry is in the same range as RGEN (100) in the Biotechnology industry. This means that CSTL’s stock grew similarly to RGEN’s over the last 12 months.

RGEN's SMR Rating (86) in the Biotechnology industry is in the same range as CSTL (87) in the null industry. This means that RGEN’s stock grew similarly to CSTL’s over the last 12 months.

CSTL's Price Growth Rating (35) in the null industry is in the same range as RGEN (44) in the Biotechnology industry. This means that CSTL’s stock grew similarly to RGEN’s over the last 12 months.

RGEN's P/E Growth Rating (32) in the Biotechnology industry is significantly better than the same rating for CSTL (99) in the null industry. This means that RGEN’s stock grew significantly faster than CSTL’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
CSTLRGEN
RSI
ODDS (%)
Bearish Trend 2 days ago
77%
Bearish Trend 2 days ago
77%
Stochastic
ODDS (%)
Bearish Trend 2 days ago
79%
Bearish Trend 2 days ago
79%
Momentum
ODDS (%)
Bullish Trend 3 days ago
78%
Bullish Trend 2 days ago
74%
MACD
ODDS (%)
Bullish Trend 2 days ago
66%
Bullish Trend 2 days ago
81%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
81%
Bullish Trend 2 days ago
74%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
76%
Bullish Trend 2 days ago
71%
Advances
ODDS (%)
Bullish Trend 2 days ago
78%
Bullish Trend 4 days ago
75%
Declines
ODDS (%)
Bearish Trend 9 days ago
82%
Bearish Trend 16 days ago
81%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
76%
Bearish Trend 2 days ago
74%
Aroon
ODDS (%)
Bullish Trend 2 days ago
86%
Bullish Trend 2 days ago
80%
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CSTL
Daily Signal:
Gain/Loss:
RGEN
Daily Signal:
Gain/Loss:
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CSTL and

Correlation & Price change

A.I.dvisor indicates that over the last year, CSTL has been loosely correlated with TCMD. These tickers have moved in lockstep 50% of the time. This A.I.-generated data suggests there is some statistical probability that if CSTL jumps, then TCMD could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To CSTL
1D Price
Change %
CSTL100%
+6.13%
TCMD - CSTL
50%
Loosely correlated
+7.19%
NTRA - CSTL
43%
Loosely correlated
+2.25%
GH - CSTL
38%
Loosely correlated
+5.03%
OFIX - CSTL
38%
Loosely correlated
+6.79%
PACB - CSTL
36%
Loosely correlated
+18.09%
More

RGEN and

Correlation & Price change

A.I.dvisor indicates that over the last year, RGEN has been closely correlated with DHR. These tickers have moved in lockstep 67% of the time. This A.I.-generated data suggests there is a high statistical probability that if RGEN jumps, then DHR could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To RGEN
1D Price
Change %
RGEN100%
+5.34%
DHR - RGEN
67%
Closely correlated
+2.34%
A - RGEN
65%
Loosely correlated
+4.27%
BIO - RGEN
60%
Loosely correlated
+4.31%
MTD - RGEN
59%
Loosely correlated
+3.78%
TMO - RGEN
58%
Loosely correlated
+2.57%
More