HOWL
Price
$1.41
Change
-$0.05 (-3.45%)
Updated
Sep 17, 04:59 PM (EDT)
Capitalization
66.31M
50 days until earnings call
OBIO
Price
$2.46
Change
-$0.07 (-2.77%)
Updated
Sep 17, 04:59 PM (EDT)
Capitalization
136.51M
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HOWL vs OBIO

Header iconHOWL vs OBIO Comparison
Open Charts HOWL vs OBIOBanner chart's image
Werewolf Therapeutics
Price$1.41
Change-$0.05 (-3.45%)
Volume$388
Capitalization66.31M
Orchestra BioMed Holdings
Price$2.46
Change-$0.07 (-2.77%)
Volume$2.58K
Capitalization136.51M
HOWL vs OBIO Comparison Chart in %
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HOWL
Daily Signalchanged days ago
Gain/Loss if bought
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OBIO
Daily Signalchanged days ago
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HOWL vs. OBIO commentary
Sep 18, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is HOWL is a Buy and OBIO is a Hold.

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COMPARISON
Comparison
Sep 18, 2025
Stock price -- (HOWL: $1.40 vs. OBIO: $2.46)
Brand notoriety: HOWL and OBIO are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: HOWL: 95% vs. OBIO: 56%
Market capitalization -- HOWL: $66.31M vs. OBIO: $136.51M
HOWL [@Biotechnology] is valued at $66.31M. OBIO’s [@Biotechnology] market capitalization is $136.51M. The market cap for tickers in the [@Biotechnology] industry ranges from $100.34B to $0. The average market capitalization across the [@Biotechnology] industry is $1.89B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

HOWL’s FA Score shows that 1 FA rating(s) are green whileOBIO’s FA Score has 0 green FA rating(s).

  • HOWL’s FA Score: 1 green, 4 red.
  • OBIO’s FA Score: 0 green, 5 red.
According to our system of comparison, HOWL is a better buy in the long-term than OBIO.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

HOWL’s TA Score shows that 7 TA indicator(s) are bullish while OBIO’s TA Score has 4 bullish TA indicator(s).

  • HOWL’s TA Score: 7 bullish, 3 bearish.
  • OBIO’s TA Score: 4 bullish, 5 bearish.
According to our system of comparison, HOWL is a better buy in the short-term than OBIO.

Price Growth

HOWL (@Biotechnology) experienced а -0.71% price change this week, while OBIO (@Biotechnology) price change was -5.56% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +1.28%. For the same industry, the average monthly price growth was +6.08%, and the average quarterly price growth was +34.58%.

Reported Earning Dates

HOWL is expected to report earnings on Nov 06, 2025.

Industries' Descriptions

@Biotechnology (+1.28% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
OBIO($137M) has a higher market cap than HOWL($66.3M). HOWL YTD gains are higher at: -5.405 vs. OBIO (-38.375). HOWL has higher annual earnings (EBITDA): -66.34M vs. OBIO (-70.94M). HOWL has more cash in the bank: 77.6M vs. OBIO (33.9M). OBIO has less debt than HOWL: OBIO (16.4M) vs HOWL (37.1M). OBIO has higher revenues than HOWL: OBIO (2.94M) vs HOWL (0).
HOWLOBIOHOWL / OBIO
Capitalization66.3M137M48%
EBITDA-66.34M-70.94M94%
Gain YTD-5.405-38.37514%
P/E RatioN/AN/A-
Revenue02.94M-
Total Cash77.6M33.9M229%
Total Debt37.1M16.4M226%
TECHNICAL ANALYSIS
Technical Analysis
HOWLOBIO
RSI
ODDS (%)
N/A
Bullish Trend 6 days ago
64%
Stochastic
ODDS (%)
Bearish Trend 2 days ago
90%
Bullish Trend 2 days ago
62%
Momentum
ODDS (%)
Bullish Trend 2 days ago
80%
Bearish Trend 2 days ago
63%
MACD
ODDS (%)
Bullish Trend 2 days ago
83%
Bearish Trend 2 days ago
47%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
82%
Bearish Trend 2 days ago
62%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
84%
Bearish Trend 2 days ago
63%
Advances
ODDS (%)
Bullish Trend 7 days ago
81%
Bullish Trend 13 days ago
62%
Declines
ODDS (%)
Bearish Trend 16 days ago
90%
Bearish Trend 8 days ago
74%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 2 days ago
60%
Aroon
ODDS (%)
Bullish Trend 2 days ago
86%
Bearish Trend 2 days ago
63%
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HOWL
Daily Signalchanged days ago
Gain/Loss if bought
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OBIO
Daily Signalchanged days ago
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HOWL and

Correlation & Price change

A.I.dvisor indicates that over the last year, HOWL has been loosely correlated with GNPX. These tickers have moved in lockstep 42% of the time. This A.I.-generated data suggests there is some statistical probability that if HOWL jumps, then GNPX could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To HOWL
1D Price
Change %
HOWL100%
-3.45%
GNPX - HOWL
42%
Loosely correlated
-13.76%
ATNM - HOWL
39%
Loosely correlated
-3.01%
BCRX - HOWL
38%
Loosely correlated
-0.32%
CLDX - HOWL
38%
Loosely correlated
-0.37%
IPSC - HOWL
38%
Loosely correlated
+1.37%
More

OBIO and

Correlation & Price change

A.I.dvisor indicates that over the last year, OBIO has been loosely correlated with XBIT. These tickers have moved in lockstep 41% of the time. This A.I.-generated data suggests there is some statistical probability that if OBIO jumps, then XBIT could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To OBIO
1D Price
Change %
OBIO100%
-2.57%
XBIT - OBIO
41%
Loosely correlated
-1.86%
ADVM - OBIO
39%
Loosely correlated
-4.64%
OCUL - OBIO
38%
Loosely correlated
-2.17%
RXRX - OBIO
38%
Loosely correlated
-2.58%
HOWL - OBIO
37%
Loosely correlated
-3.45%
More