IONS
Price
$81.99
Change
-$0.74 (-0.89%)
Updated
Dec 1 closing price
Capitalization
13.28B
85 days until earnings call
Intraday BUY SELL Signals
RARE
Price
$33.37
Change
-$1.38 (-3.97%)
Updated
Dec 1 closing price
Capitalization
3.22B
72 days until earnings call
Intraday BUY SELL Signals
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IONS vs RARE

Header iconIONS vs RARE Comparison
Open Charts IONS vs RAREBanner chart's image
Ionis Pharmaceuticals
Price$81.99
Change-$0.74 (-0.89%)
Volume$1.87M
Capitalization13.28B
Ultragenyx Pharmaceutical
Price$33.37
Change-$1.38 (-3.97%)
Volume$1.04M
Capitalization3.22B
IONS vs RARE Comparison Chart in %
IONS
Daily Signal:
Gain/Loss:
RARE
Daily Signal:
Gain/Loss:
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VS
IONS vs. RARE commentary
Dec 02, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is IONS is a StrongBuy and RARE is a StrongBuy.

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COMPARISON
Comparison
Dec 02, 2025
Stock price -- (IONS: $81.99 vs. RARE: $33.37)
Brand notoriety: IONS and RARE are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: IONS: 72% vs. RARE: 75%
Market capitalization -- IONS: $13.28B vs. RARE: $3.22B
IONS [@Biotechnology] is valued at $13.28B. RARE’s [@Biotechnology] market capitalization is $3.22B. The market cap for tickers in the [@Biotechnology] industry ranges from $107.98B to $0. The average market capitalization across the [@Biotechnology] industry is $2.19B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

IONS’s FA Score shows that 0 FA rating(s) are green whileRARE’s FA Score has 0 green FA rating(s).

  • IONS’s FA Score: 0 green, 5 red.
  • RARE’s FA Score: 0 green, 5 red.
According to our system of comparison, IONS is a better buy in the long-term than RARE.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

IONS’s TA Score shows that 4 TA indicator(s) are bullish while RARE’s TA Score has 5 bullish TA indicator(s).

  • IONS’s TA Score: 4 bullish, 4 bearish.
  • RARE’s TA Score: 5 bullish, 3 bearish.
According to our system of comparison, RARE is a better buy in the short-term than IONS.

Price Growth

IONS (@Biotechnology) experienced а +4.42% price change this week, while RARE (@Biotechnology) price change was +1.80% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +1.58%. For the same industry, the average monthly price growth was -2.68%, and the average quarterly price growth was +56.80%.

Reported Earning Dates

IONS is expected to report earnings on Feb 25, 2026.

RARE is expected to report earnings on Feb 12, 2026.

Industries' Descriptions

@Biotechnology (+1.58% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
IONS($13.3B) has a higher market cap than RARE($3.22B). IONS YTD gains are higher at: 134.525 vs. RARE (-20.680). IONS has higher annual earnings (EBITDA): -153.61M vs. RARE (-435.33M). IONS has more cash in the bank: 2.24B vs. RARE (477M). RARE has less debt than IONS: RARE (36.3M) vs IONS (1.49B). IONS has higher revenues than RARE: IONS (967M) vs RARE (610M).
IONSRAREIONS / RARE
Capitalization13.3B3.22B413%
EBITDA-153.61M-435.33M35%
Gain YTD134.525-20.680-651%
P/E RatioN/AN/A-
Revenue967M610M159%
Total Cash2.24B477M470%
Total Debt1.49B36.3M4,102%
FUNDAMENTALS RATINGS
IONS vs RARE: Fundamental Ratings
IONS
RARE
OUTLOOK RATING
1..100
139
VALUATION
overvalued / fair valued / undervalued
1..100
100
Overvalued
96
Overvalued
PROFIT vs RISK RATING
1..100
48100
SMR RATING
1..100
9599
PRICE GROWTH RATING
1..100
3555
P/E GROWTH RATING
1..100
55100
SEASONALITY SCORE
1..100
5018

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

RARE's Valuation (96) in the Biotechnology industry is in the same range as IONS (100). This means that RARE’s stock grew similarly to IONS’s over the last 12 months.

IONS's Profit vs Risk Rating (48) in the Biotechnology industry is somewhat better than the same rating for RARE (100). This means that IONS’s stock grew somewhat faster than RARE’s over the last 12 months.

IONS's SMR Rating (95) in the Biotechnology industry is in the same range as RARE (99). This means that IONS’s stock grew similarly to RARE’s over the last 12 months.

IONS's Price Growth Rating (35) in the Biotechnology industry is in the same range as RARE (55). This means that IONS’s stock grew similarly to RARE’s over the last 12 months.

IONS's P/E Growth Rating (55) in the Biotechnology industry is somewhat better than the same rating for RARE (100). This means that IONS’s stock grew somewhat faster than RARE’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
IONSRARE
RSI
ODDS (%)
Bearish Trend 1 day ago
59%
N/A
Stochastic
ODDS (%)
Bearish Trend 1 day ago
74%
Bearish Trend 1 day ago
80%
Momentum
ODDS (%)
Bullish Trend 1 day ago
74%
Bullish Trend 1 day ago
76%
MACD
ODDS (%)
Bullish Trend 1 day ago
71%
Bullish Trend 1 day ago
75%
TrendWeek
ODDS (%)
Bullish Trend 1 day ago
71%
Bearish Trend 1 day ago
80%
TrendMonth
ODDS (%)
Bullish Trend 1 day ago
73%
Bearish Trend 1 day ago
82%
Advances
ODDS (%)
Bullish Trend 4 days ago
67%
Bullish Trend 4 days ago
78%
Declines
ODDS (%)
Bearish Trend 12 days ago
66%
Bearish Trend 12 days ago
81%
BollingerBands
ODDS (%)
Bearish Trend 1 day ago
69%
Bearish Trend 1 day ago
87%
Aroon
ODDS (%)
Bullish Trend 1 day ago
70%
Bullish Trend 1 day ago
72%
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IONS
Daily Signal:
Gain/Loss:
RARE
Daily Signal:
Gain/Loss:
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