ONC
Price
$356.01
Change
-$3.04 (-0.85%)
Updated
Aug 13 closing price
Capitalization
42.88B
83 days until earnings call
Intraday BUY SELL Signals
VRTX
Price
$505.09
Change
-$11.35 (-2.20%)
Updated
Aug 14, 12:14 PM (EDT)
Capitalization
130.9B
87 days until earnings call
Intraday BUY SELL Signals
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ONC vs VRTX

ONC vs VRTX Comparison Chart in %
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ONC vs. VRTX commentary
Aug 14, 2026

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is ONC is a Buy and VRTX is a StrongBuy.

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COMPARISON
Comparison
Aug 14, 2026
Stock price -- (ONC: $356.01 vs. VRTX: $516.44)
Brand notoriety: ONC and VRTX are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: ONC: 78% vs. VRTX: 42%
Market capitalization -- ONC: $42.88B vs. VRTX: $130.9B
ONC [@Biotechnology] is valued at $42.88B. VRTX’s [@Biotechnology] market capitalization is $130.9B. The market cap for tickers in the [@Biotechnology] industry ranges from $130.9B to $0. The average market capitalization across the [@Biotechnology] industry is $2.23B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

ONC’s FA Score shows that 0 FA rating(s) are green whileVRTX’s FA Score has 2 green FA rating(s).

  • ONC’s FA Score: 0 green, 5 red.
  • VRTX’s FA Score: 2 green, 3 red.
According to our system of comparison, VRTX is a better buy in the long-term than ONC.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

ONC’s TA Score shows that 3 TA indicator(s) are bullish while VRTX’s TA Score has 4 bullish TA indicator(s).

  • ONC’s TA Score: 3 bullish, 4 bearish.
  • VRTX’s TA Score: 4 bullish, 4 bearish.
According to our system of comparison, VRTX is a better buy in the short-term than ONC.

Price Growth

ONC (@Biotechnology) experienced а +7.95% price change this week, while VRTX (@Biotechnology) price change was +6.70% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +1.08%. For the same industry, the average monthly price growth was -1.56%, and the average quarterly price growth was +3040.81%.

Reported Earning Dates

ONC is expected to report earnings on Nov 05, 2026.

VRTX is expected to report earnings on Nov 09, 2026.

Industries' Descriptions

@Biotechnology (+1.08% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
VRTX($131B) has a higher market cap than ONC($42.9B). ONC has higher P/E ratio than VRTX: ONC (63.69) vs VRTX (30.08). ONC YTD gains are higher at: 17.182 vs. VRTX (13.914). VRTX has higher annual earnings (EBITDA): 4.98B vs. ONC (889M). VRTX has more cash in the bank: 7.25B vs. ONC (4.79B). ONC has less debt than VRTX: ONC (1.15B) vs VRTX (1.99B). VRTX has higher revenues than ONC: VRTX (12.2B) vs ONC (5.74B).
ONCVRTXONC / VRTX
Capitalization42.9B131B33%
EBITDA889M4.98B18%
Gain YTD17.18213.914123%
P/E Ratio63.6930.08212%
Revenue5.74B12.2B47%
Total Cash4.79B7.25B66%
Total Debt1.15B1.99B58%
FUNDAMENTALS RATINGS
ONC vs VRTX: Fundamental Ratings
ONC
VRTX
OUTLOOK RATING
1..100
4380
VALUATION
overvalued / fair valued / undervalued
1..100
88
Overvalued
84
Overvalued
PROFIT vs RISK RATING
1..100
9222
SMR RATING
1..100
6441
PRICE GROWTH RATING
1..100
4223
P/E GROWTH RATING
1..100
10042
SEASONALITY SCORE
1..100
8555

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

VRTX's Valuation (84) in the Biotechnology industry is in the same range as ONC (88). This means that VRTX’s stock grew similarly to ONC’s over the last 12 months.

VRTX's Profit vs Risk Rating (22) in the Biotechnology industry is significantly better than the same rating for ONC (92). This means that VRTX’s stock grew significantly faster than ONC’s over the last 12 months.

VRTX's SMR Rating (41) in the Biotechnology industry is in the same range as ONC (64). This means that VRTX’s stock grew similarly to ONC’s over the last 12 months.

VRTX's Price Growth Rating (23) in the Biotechnology industry is in the same range as ONC (42). This means that VRTX’s stock grew similarly to ONC’s over the last 12 months.

VRTX's P/E Growth Rating (42) in the Biotechnology industry is somewhat better than the same rating for ONC (100). This means that VRTX’s stock grew somewhat faster than ONC’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
ONCVRTX
RSI
ODDS (%)
Bearish Trend 1 day ago
69%
Bearish Trend 1 day ago
61%
Stochastic
ODDS (%)
Bearish Trend 1 day ago
75%
Bearish Trend 1 day ago
53%
Momentum
ODDS (%)
N/A
Bullish Trend 1 day ago
70%
MACD
ODDS (%)
Bullish Trend 1 day ago
74%
Bullish Trend 1 day ago
57%
TrendWeek
ODDS (%)
Bullish Trend 1 day ago
74%
Bullish Trend 1 day ago
65%
TrendMonth
ODDS (%)
Bullish Trend 1 day ago
71%
Bullish Trend 1 day ago
70%
Advances
ODDS (%)
Bullish Trend 4 days ago
74%
Bullish Trend 4 days ago
64%
Declines
ODDS (%)
Bearish Trend 1 day ago
75%
Bearish Trend 1 day ago
43%
BollingerBands
ODDS (%)
Bearish Trend 1 day ago
74%
Bearish Trend 1 day ago
57%
Aroon
ODDS (%)
Bullish Trend 1 day ago
72%
Bullish Trend 1 day ago
61%
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ONC
Daily Signal:
Gain/Loss:
VRTX
Daily Signal:
Gain/Loss:
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ONC and

Correlation & Price change

A.I.dvisor indicates that over the last year, ONC has been loosely correlated with ZLAB. These tickers have moved in lockstep 38% of the time. This A.I.-generated data suggests there is some statistical probability that if ONC jumps, then ZLAB could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To ONC
1D Price
Change %
ONC100%
-0.85%
ZLAB - ONC
38%
Loosely correlated
+2.12%
AXON - ONC
37%
Loosely correlated
+2.64%
GOSS - ONC
35%
Loosely correlated
-4.11%
VRTX - ONC
34%
Loosely correlated
-1.77%
AMRN - ONC
33%
Loosely correlated
+0.64%
More