PLRX
Price
$1.46
Change
-$0.07 (-4.58%)
Updated
Sep 17 closing price
Capitalization
93.92M
54 days until earnings call
PRME
Price
$4.65
Change
-$0.02 (-0.43%)
Updated
Sep 17 closing price
Capitalization
832.54M
43 days until earnings call
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PLRX vs PRME

Header iconPLRX vs PRME Comparison
Open Charts PLRX vs PRMEBanner chart's image
Pliant Therapeutics
Price$1.46
Change-$0.07 (-4.58%)
Volume$535.2K
Capitalization93.92M
Prime Medicine
Price$4.65
Change-$0.02 (-0.43%)
Volume$4.04M
Capitalization832.54M
PLRX vs PRME Comparison Chart in %
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PLRX
Daily Signalchanged days ago
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PRME
Daily Signalchanged days ago
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PLRX vs. PRME commentary
Sep 18, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is PLRX is a Hold and PRME is a Buy.

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COMPARISON
Comparison
Sep 18, 2025
Stock price -- (PLRX: $1.47 vs. PRME: $4.64)
Brand notoriety: PLRX and PRME are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: PLRX: 56% vs. PRME: 104%
Market capitalization -- PLRX: $93.92M vs. PRME: $832.54M
PLRX [@Biotechnology] is valued at $93.92M. PRME’s [@Biotechnology] market capitalization is $832.54M. The market cap for tickers in the [@Biotechnology] industry ranges from $100.34B to $0. The average market capitalization across the [@Biotechnology] industry is $1.89B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

PLRX’s FA Score shows that 0 FA rating(s) are green whilePRME’s FA Score has 0 green FA rating(s).

  • PLRX’s FA Score: 0 green, 5 red.
  • PRME’s FA Score: 0 green, 5 red.
According to our system of comparison, PRME is a better buy in the long-term than PLRX.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

PLRX’s TA Score shows that 2 TA indicator(s) are bullish while PRME’s TA Score has 5 bullish TA indicator(s).

  • PLRX’s TA Score: 2 bullish, 6 bearish.
  • PRME’s TA Score: 5 bullish, 5 bearish.
According to our system of comparison, PRME is a better buy in the short-term than PLRX.

Price Growth

PLRX (@Biotechnology) experienced а -13.31% price change this week, while PRME (@Biotechnology) price change was +19.41% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +1.28%. For the same industry, the average monthly price growth was +6.08%, and the average quarterly price growth was +34.58%.

Reported Earning Dates

PLRX is expected to report earnings on Nov 11, 2025.

PRME is expected to report earnings on Oct 31, 2025.

Industries' Descriptions

@Biotechnology (+1.28% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
PRME($833M) has a higher market cap than PLRX($93.9M). PRME YTD gains are higher at: 59.075 vs. PLRX (-88.876). PRME (-197.38M) and PLRX (-201.76M) have comparable annual earnings (EBITDA) . PLRX has more cash in the bank: 263M vs. PRME (102M). PLRX has less debt than PRME: PLRX (60.4M) vs PRME (120M). PRME has higher revenues than PLRX: PRME (4.96M) vs PLRX (0).
PLRXPRMEPLRX / PRME
Capitalization93.9M833M11%
EBITDA-201.76M-197.38M102%
Gain YTD-88.87659.075-150%
P/E RatioN/AN/A-
Revenue04.96M-
Total Cash263M102M258%
Total Debt60.4M120M50%
FUNDAMENTALS RATINGS
PRME: Fundamental Ratings
PRME
OUTLOOK RATING
1..100
8
VALUATION
overvalued / fair valued / undervalued
1..100
70
Overvalued
PROFIT vs RISK RATING
1..100
100
SMR RATING
1..100
99
PRICE GROWTH RATING
1..100
35
P/E GROWTH RATING
1..100
100
SEASONALITY SCORE
1..100
38

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

TECHNICAL ANALYSIS
Technical Analysis
PLRXPRME
RSI
ODDS (%)
N/A
Bearish Trend 1 day ago
90%
Stochastic
ODDS (%)
Bullish Trend 1 day ago
77%
Bearish Trend 1 day ago
90%
Momentum
ODDS (%)
Bearish Trend 1 day ago
90%
Bullish Trend 1 day ago
90%
MACD
ODDS (%)
Bearish Trend 1 day ago
90%
Bullish Trend 1 day ago
81%
TrendWeek
ODDS (%)
Bearish Trend 1 day ago
88%
Bullish Trend 1 day ago
82%
TrendMonth
ODDS (%)
Bearish Trend 1 day ago
88%
Bullish Trend 1 day ago
77%
Advances
ODDS (%)
Bullish Trend 15 days ago
77%
Bullish Trend 9 days ago
79%
Declines
ODDS (%)
Bearish Trend 3 days ago
87%
Bearish Trend 3 days ago
89%
BollingerBands
ODDS (%)
Bearish Trend 1 day ago
82%
Bearish Trend 1 day ago
90%
Aroon
ODDS (%)
Bearish Trend 1 day ago
89%
Bearish Trend 1 day ago
82%
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PLRX
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PRME
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PLRX and

Correlation & Price change

A.I.dvisor indicates that over the last year, PLRX has been loosely correlated with OCUL. These tickers have moved in lockstep 42% of the time. This A.I.-generated data suggests there is some statistical probability that if PLRX jumps, then OCUL could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To PLRX
1D Price
Change %
PLRX100%
-4.25%
OCUL - PLRX
42%
Loosely correlated
-2.17%
ITRM - PLRX
41%
Loosely correlated
-2.09%
SRRK - PLRX
41%
Loosely correlated
-1.14%
FHTX - PLRX
40%
Loosely correlated
-2.04%
LXRX - PLRX
39%
Loosely correlated
-0.45%
More

PRME and

Correlation & Price change

A.I.dvisor indicates that over the last year, PRME has been loosely correlated with CRSP. These tickers have moved in lockstep 57% of the time. This A.I.-generated data suggests there is some statistical probability that if PRME jumps, then CRSP could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To PRME
1D Price
Change %
PRME100%
-0.54%
CRSP - PRME
57%
Loosely correlated
-3.46%
BEAM - PRME
53%
Loosely correlated
-1.86%
RXRX - PRME
52%
Loosely correlated
-2.58%
CRBU - PRME
47%
Loosely correlated
-4.17%
EDIT - PRME
46%
Loosely correlated
-3.89%
More