SAVA
Price
$3.69
Change
-$0.29 (-7.29%)
Updated
Oct 22, 01:22 PM (EDT)
Capitalization
192.27M
14 days until earnings call
Intraday Buy/Sell Signals
SPRO
Price
$2.27
Change
-$0.10 (-4.22%)
Updated
Oct 22, 01:59 PM (EDT)
Capitalization
133.37M
26 days until earnings call
Intraday Buy/Sell Signals
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SAVA vs SPRO

Header iconSAVA vs SPRO Comparison
Open Charts SAVA vs SPROBanner chart's image
Cassava Sciences
Price$3.69
Change-$0.29 (-7.29%)
Volume$3.16K
Capitalization192.27M
Spero Therapeutics
Price$2.27
Change-$0.10 (-4.22%)
Volume$5.1K
Capitalization133.37M
SAVA vs SPRO Comparison Chart in %
SAVA
Daily Signalchanged days ago
Gain/Loss if bought
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SPRO
Daily Signalchanged days ago
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SAVA vs. SPRO commentary
Oct 22, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is SAVA is a Hold and SPRO is a Hold.

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COMPARISON
Comparison
Oct 22, 2025
Stock price -- (SAVA: $3.98 vs. SPRO: $2.37)
Brand notoriety: SAVA and SPRO are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: SAVA: 80% vs. SPRO: 1928%
Market capitalization -- SAVA: $192.27M vs. SPRO: $133.37M
SAVA [@Biotechnology] is valued at $192.27M. SPRO’s [@Biotechnology] market capitalization is $133.37M. The market cap for tickers in the [@Biotechnology] industry ranges from $109.29B to $0. The average market capitalization across the [@Biotechnology] industry is $2.07B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

SAVA’s FA Score shows that 1 FA rating(s) are green whileSPRO’s FA Score has 1 green FA rating(s).

  • SAVA’s FA Score: 1 green, 4 red.
  • SPRO’s FA Score: 1 green, 4 red.
According to our system of comparison, SPRO is a better buy in the long-term than SAVA.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

SAVA’s TA Score shows that 7 TA indicator(s) are bullish while SPRO’s TA Score has 4 bullish TA indicator(s).

  • SAVA’s TA Score: 7 bullish, 4 bearish.
  • SPRO’s TA Score: 4 bullish, 5 bearish.
According to our system of comparison, SAVA is a better buy in the short-term than SPRO.

Price Growth

SAVA (@Biotechnology) experienced а -10.16% price change this week, while SPRO (@Biotechnology) price change was +0.42% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was -2.72%. For the same industry, the average monthly price growth was +9.91%, and the average quarterly price growth was +61.40%.

Reported Earning Dates

SAVA is expected to report earnings on Nov 05, 2025.

SPRO is expected to report earnings on Nov 17, 2025.

Industries' Descriptions

@Biotechnology (-2.72% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
SAVA($192M) has a higher market cap than SPRO($133M). SPRO YTD gains are higher at: 130.097 vs. SAVA (68.644). SPRO has higher annual earnings (EBITDA): -56.36M vs. SAVA (-129.96M). SAVA has more cash in the bank: 112M vs. SPRO (31.2M). SAVA has less debt than SPRO: SAVA (0) vs SPRO (3.62M). SPRO has higher revenues than SAVA: SPRO (34.1M) vs SAVA (0).
SAVASPROSAVA / SPRO
Capitalization192M133M144%
EBITDA-129.96M-56.36M231%
Gain YTD68.644130.09753%
P/E RatioN/A10.75-
Revenue034.1M-
Total Cash112M31.2M359%
Total Debt03.62M-
FUNDAMENTALS RATINGS
SAVA vs SPRO: Fundamental Ratings
SAVA
SPRO
OUTLOOK RATING
1..100
2429
VALUATION
overvalued / fair valued / undervalued
1..100
26
Undervalued
59
Fair valued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
9999
PRICE GROWTH RATING
1..100
3637
P/E GROWTH RATING
1..100
1006
SEASONALITY SCORE
1..100
5050

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

SAVA's Valuation (26) in the Pharmaceuticals Other industry is somewhat better than the same rating for SPRO (59) in the Pharmaceuticals Major industry. This means that SAVA’s stock grew somewhat faster than SPRO’s over the last 12 months.

SAVA's Profit vs Risk Rating (100) in the Pharmaceuticals Other industry is in the same range as SPRO (100) in the Pharmaceuticals Major industry. This means that SAVA’s stock grew similarly to SPRO’s over the last 12 months.

SAVA's SMR Rating (99) in the Pharmaceuticals Other industry is in the same range as SPRO (99) in the Pharmaceuticals Major industry. This means that SAVA’s stock grew similarly to SPRO’s over the last 12 months.

SAVA's Price Growth Rating (36) in the Pharmaceuticals Other industry is in the same range as SPRO (37) in the Pharmaceuticals Major industry. This means that SAVA’s stock grew similarly to SPRO’s over the last 12 months.

SPRO's P/E Growth Rating (6) in the Pharmaceuticals Major industry is significantly better than the same rating for SAVA (100) in the Pharmaceuticals Other industry. This means that SPRO’s stock grew significantly faster than SAVA’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
SAVASPRO
RSI
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 2 days ago
90%
Stochastic
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 2 days ago
83%
Momentum
ODDS (%)
Bullish Trend 3 days ago
82%
Bullish Trend 2 days ago
74%
MACD
ODDS (%)
Bullish Trend 2 days ago
80%
N/A
TrendWeek
ODDS (%)
Bearish Trend 2 days ago
87%
Bullish Trend 2 days ago
74%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
84%
Bullish Trend 2 days ago
75%
Advances
ODDS (%)
Bullish Trend 8 days ago
84%
Bullish Trend 2 days ago
69%
Declines
ODDS (%)
Bearish Trend 6 days ago
87%
Bearish Trend 6 days ago
90%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 2 days ago
85%
Aroon
ODDS (%)
Bullish Trend 2 days ago
90%
Bearish Trend 2 days ago
86%
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SAVA
Daily Signalchanged days ago
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SPRO
Daily Signalchanged days ago
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SAVA and

Correlation & Price change

A.I.dvisor indicates that over the last year, SAVA has been loosely correlated with CRSP. These tickers have moved in lockstep 35% of the time. This A.I.-generated data suggests there is some statistical probability that if SAVA jumps, then CRSP could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SAVA
1D Price
Change %
SAVA100%
-9.75%
CRSP - SAVA
35%
Loosely correlated
-2.23%
IBRX - SAVA
29%
Poorly correlated
-0.41%
LXRX - SAVA
26%
Poorly correlated
-5.26%
AMRN - SAVA
26%
Poorly correlated
-1.53%
ONCO - SAVA
26%
Poorly correlated
+6.41%
More