SPRO
Price
$1.94
Change
-$0.43 (-18.22%)
Updated
Aug 13 closing price
Capitalization
108.19M
95 days until earnings call
VIGL
Price
$8.05
Change
-$0.00 (-0.00%)
Updated
Aug 4 closing price
Capitalization
375.71M
85 days until earnings call
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SPRO vs VIGL

Header iconSPRO vs VIGL Comparison
Open Charts SPRO vs VIGLBanner chart's image
Spero Therapeutics
Price$1.94
Change-$0.43 (-18.22%)
Volume$2.49M
Capitalization108.19M
Vigil Neuroscience
Price$8.05
Change-$0.00 (-0.00%)
Volume$5.51M
Capitalization375.71M
SPRO vs VIGL Comparison Chart in %
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SPRO
Daily Signalchanged days ago
Gain/Loss if bought
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VIGL
Daily Signalchanged days ago
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SPRO vs. VIGL commentary
Aug 14, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is SPRO is a Buy and VIGL is a Hold.

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COMPARISON
Comparison
Aug 14, 2025
Stock price -- (SPRO: $1.93 vs. VIGL: $8.05)
Brand notoriety: SPRO and VIGL are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: SPRO: 227% vs. VIGL: 301%
Market capitalization -- SPRO: $108.19M vs. VIGL: $375.71M
SPRO [@Biotechnology] is valued at $108.19M. VIGL’s [@Biotechnology] market capitalization is $375.71M. The market cap for tickers in the [@Biotechnology] industry ranges from $101.51B to $0. The average market capitalization across the [@Biotechnology] industry is $1.79B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

SPRO’s FA Score shows that 1 FA rating(s) are green whileVIGL’s FA Score has 0 green FA rating(s).

  • SPRO’s FA Score: 1 green, 4 red.
  • VIGL’s FA Score: 0 green, 5 red.
According to our system of comparison, SPRO is a better buy in the long-term than VIGL.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

SPRO’s TA Score shows that 6 TA indicator(s) are bullish while VIGL’s TA Score has 3 bullish TA indicator(s).

  • SPRO’s TA Score: 6 bullish, 4 bearish.
  • VIGL’s TA Score: 3 bullish, 4 bearish.
According to our system of comparison, SPRO is a better buy in the short-term than VIGL.

Price Growth

SPRO (@Biotechnology) experienced а -14.38% price change this week, while VIGL (@Biotechnology) price change was 0.00% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +14.81%. For the same industry, the average monthly price growth was +26.20%, and the average quarterly price growth was +20.07%.

Reported Earning Dates

SPRO is expected to report earnings on Nov 17, 2025.

VIGL is expected to report earnings on Nov 06, 2025.

Industries' Descriptions

@Biotechnology (+14.81% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
VIGL($376M) has a higher market cap than SPRO($108M). VIGL YTD gains are higher at: 373.529 vs. SPRO (87.864). SPRO has higher annual earnings (EBITDA): -73.06M vs. VIGL (-91.27M). VIGL has more cash in the bank: 87.1M vs. SPRO (48.9M). SPRO has less debt than VIGL: SPRO (3.96M) vs VIGL (12.7M). SPRO has higher revenues than VIGL: SPRO (28.3M) vs VIGL (0).
SPROVIGLSPRO / VIGL
Capitalization108M376M29%
EBITDA-73.06M-91.27M80%
Gain YTD87.864373.52924%
P/E Ratio10.75N/A-
Revenue28.3M0-
Total Cash48.9M87.1M56%
Total Debt3.96M12.7M31%
FUNDAMENTALS RATINGS
SPRO: Fundamental Ratings
SPRO
OUTLOOK RATING
1..100
51
VALUATION
overvalued / fair valued / undervalued
1..100
51
Fair valued
PROFIT vs RISK RATING
1..100
100
SMR RATING
1..100
98
PRICE GROWTH RATING
1..100
35
P/E GROWTH RATING
1..100
6
SEASONALITY SCORE
1..100
90

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

TECHNICAL ANALYSIS
Technical Analysis
SPROVIGL
RSI
ODDS (%)
Bullish Trend 1 day ago
86%
Bearish Trend 2 days ago
90%
Stochastic
ODDS (%)
Bullish Trend 1 day ago
81%
Bullish Trend 2 days ago
77%
Momentum
ODDS (%)
Bearish Trend 1 day ago
90%
Bearish Trend 2 days ago
86%
MACD
ODDS (%)
Bearish Trend 1 day ago
90%
N/A
TrendWeek
ODDS (%)
Bearish Trend 1 day ago
89%
Bullish Trend 2 days ago
83%
TrendMonth
ODDS (%)
Bearish Trend 1 day ago
90%
Bullish Trend 2 days ago
81%
Advances
ODDS (%)
Bullish Trend 2 days ago
72%
Bullish Trend about 1 month ago
87%
Declines
ODDS (%)
Bearish Trend 9 days ago
90%
Bearish Trend 14 days ago
88%
BollingerBands
ODDS (%)
Bullish Trend 1 day ago
88%
Bearish Trend 3 days ago
68%
Aroon
ODDS (%)
Bearish Trend 1 day ago
90%
Bullish Trend 2 days ago
66%
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SPRO
Daily Signalchanged days ago
Gain/Loss if bought
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VIGL
Daily Signalchanged days ago
Gain/Loss if bought
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SPRO and

Correlation & Price change

A.I.dvisor indicates that over the last year, SPRO has been loosely correlated with ASBP. These tickers have moved in lockstep 58% of the time. This A.I.-generated data suggests there is some statistical probability that if SPRO jumps, then ASBP could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SPRO
1D Price
Change %
SPRO100%
-18.01%
ASBP - SPRO
58%
Loosely correlated
+10.83%
CLGN - SPRO
38%
Loosely correlated
-13.65%
ITOS - SPRO
35%
Loosely correlated
+0.20%
XENE - SPRO
32%
Poorly correlated
+4.67%
MGTX - SPRO
30%
Poorly correlated
+3.99%
More