Azitra Inc is an early-stage clinical biopharmaceutical company focused on developing therapies for precision dermatology using engineered proteins and live biotherapeutic products... Show more
Azitra, Inc. is a clinical-stage biopharmaceutical company focused on precision dermatology. Headquartered in Branford, Connecticut, and founded in 2014, the company develops engineered proteins and topical live biotherapeutic products built on Staphylococcus epidermidis to treat skin diseases. Its lead therapeutic candidate, ATR-12, is in Phase 1b/2a development for Netherton syndrome, a rare genetic skin disorder. The company is also advancing ATR-04, a Fast Track-designated candidate for the skin rash associated with EGFR inhibitor cancer therapy, and ATR-01 for ichthyosis vulgaris. Azitra maintains a joint development agreement with Bayer and a proprietary microbial library of roughly 1,500 unique strains. Investors follow the stock for its rare-disease pipeline and dermatology platform, though as a pre-revenue, clinical-stage company it carries elevated financing and execution risk.
Over the last 30 days, Azitra shares declined approximately 34.5%, moving from a split-adjusted close of $1.695 in late September to about $1.11 in late October. The path was far from linear: the stock slid steadily through the first half of October before a dramatic single-session rebound on October 26, followed by renewed selling pressure.
Looking at the broader three-month period, the stock is down roughly 14.7%, from a split-adjusted close near $1.30 in late July to about $1.11. The quarterly trend peaked in late August, when shares reached approximately $1.86, before a sustained retreat into September and October. All figures are adjusted for the 1-for-10 reverse stock split to provide a like-for-like comparison.
The dominant driver was a prolonged decline that pushed the shares into penny-stock territory. In mid-October, the company announced a 1-for-10 reverse stock split, approved by the board on October 14 and effective October 26, reducing the issued share count from about 60.6 million to roughly 6.06 million. The move was aimed at regaining compliance with NYSE American continued-listing requirements, and it underscored the pressure the stock had faced.
On the clinical front, Azitra reported on October 1 that its Phase 1/2 trial of ATR-04 had completed the first cohort and that the safety review committee recommended advancing to cohort 2. On October 26, the company released ex vivo data for ATR-COSF, a cosmetic candidate, showing a roughly 50% reduction in the appearance of wrinkles 48 hours after a single application. The stock surged more than 100% intraday on the news, and the company separately announced the suspension of its at-the-market offering program. The rally proved short-lived, however, and shares pulled back sharply in subsequent sessions as investors weighed the early-stage nature of the data against the company's small market capitalization and financing needs.
The broader multi-month narrative centers on a clinical-stage company contending with a declining share price and a shrinking capital base. After reaching a late-August high near $1.86, the stock lost momentum through September and October as financing concerns mounted and the shares drifted toward a dollar threshold that triggered the reverse stock split. The capital-structure reset, combined with the early-stage ATR-COSF data and the ATR-04 cohort advancement, shaped the quarter's overall trajectory: sustained weakness punctuated by brief, news-driven spikes in volatility.
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Several factors are likely to shape Azitra's share price in the months ahead. The company has said initial human clinical data for ATR-COSF is anticipated before the end of 2026, with additional details expected at the BIO-Europe conference in November. Continued enrollment and safety readouts from the ATR-04 Phase 1/2 cohort 2 will also be closely watched, as will progress on ATR-12 for Netherton syndrome. On the financial side, the company's small market capitalization, pre-revenue status, and need for additional funding remain key risk factors, particularly given the recent suspension of its at-the-market offering program and the possibility that it may pursue other financing transactions. Investors should monitor clinical milestones, regulatory developments, and capital-raising activity rather than relying on short-term price swings.
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The 10-day RSI Oscillator for AZTR moved out of overbought territory on October 27, 2026. This could be a sign that the stock is shifting from an upward trend to a downward trend. Traders may want to look at selling the stock or buying put options. Tickeron's A.I.dvisor looked at 9 instances where the indicator moved out of the overbought zone. In 9 of the 9 cases the stock moved lower in the days that followed. This puts the odds of a move down at 90%.
The Momentum Indicator moved below the 0 level on November 09, 2026. You may want to consider selling the stock, shorting the stock, or exploring put options on AZTR as a result. In 55 of 56 cases where the Momentum Indicator fell below 0, the stock fell further within the subsequent month. The odds of a continued downward trend are 90%.
The Moving Average Convergence Divergence Histogram (MACD) for AZTR turned negative on November 10, 2026. This could be a sign that the stock is set to turn lower in the coming weeks. Traders may want to sell the stock or buy put options. Tickeron's A.I.dvisor looked at 30 similar instances when the indicator turned negative. In 28 of the 30 cases the stock turned lower in the days that followed. This puts the odds of success at 90%.
AZTR moved below its 50-day moving average on October 27, 2026 date and that indicates a change from an upward trend to a downward trend.
Following a 3-day decline, the stock is projected to fall further. Considering past instances where AZTR declined for three days, the price rose further in 50 of 62 cases within the following month. The odds of a continued downward trend are 90%.
The Aroon Indicator for AZTR entered a downward trend on October 23, 2026. This could indicate a strong downward move is ahead for the stock. Traders may want to consider selling the stock or buying put options.
The Stochastic Oscillator shows that the ticker has stayed in the oversold zone for 8 days. The price of this ticker is presumed to bounce back soon, since the longer the ticker stays in the oversold zone, the more promptly an upward trend is expected.
Following a +14.90% 3-day Advance, the price is estimated to grow further. Considering data from situations where AZTR advanced for three days, in 119 of 147 cases, the price rose further within the following month. The odds of a continued upward trend are 81%.
AZTR may jump back above the lower band and head toward the middle band. Traders may consider buying the stock or exploring call options.
The Tickeron PE Growth Rating for this company is 1 (best 1 - 100 worst), pointing to outstanding earnings growth. The PE Growth rating is based on a comparative analysis of stock PE ratio increase over the last 12 months compared against S&P 500 index constituents.
The Tickeron Valuation Rating of 91 (best 1 - 100 worst) indicates that the company is significantly overvalued in the industry. This rating compares market capitalization estimated by our proprietary formula with the current market capitalization. This rating is based on the following metrics, as compared to industry averages: P/B Ratio (6.053) is normal, around the industry mean (3.498). P/E Ratio (36.625) is within average values for comparable stocks, (-1.193). Projected Growth (PEG Ratio) (0.000) is also within normal values, averaging (9.059). Dividend Yield (0.000) settles around the average of (130.981) among similar stocks. P/S Ratio (146.534) is also within normal values, averaging (440.869).
The Tickeron Price Growth Rating for this company is 95 (best 1 - 100 worst), indicating slightly worse than average price growth. AZTR’s price grows at a lower rate over the last 12 months as compared to S&P 500 index constituents.
The Tickeron SMR rating for this company is 100 (best 1 - 100 worst), indicating weak sales and an unprofitable business model. SMR (Sales, Margin, Return on Equity) rating is based on comparative analysis of weighted Sales, Income Margin and Return on Equity values compared against S&P 500 index constituents. The weighted SMR value is a proprietary formula developed by Tickeron and represents an overall profitability measure for a stock.
The Tickeron Profit vs. Risk Rating rating for this company is 100 (best 1 - 100 worst), indicating that the returns do not compensate for the risks. AZTR’s unstable profits reported over time resulted in significant Drawdowns within these last five years. A stable profit reduces stock drawdown and volatility. The average Profit vs. Risk Rating rating for the industry is 93, placing this stock worse than average.
The average fundamental analysis ratings, where 1 is best and 100 is worst, are as follows
Industry Biotechnology