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CDIO stock forecast, quote, news & analysis

Cardio Diagnostics Holdings Inc is a medical technology company focused on developing and commercializing epigenetics-based clinical tests for cardiovascular diseases and associated comorbidities by leveraging its Artificial Intelligence (AI)-driven Multi-Omics Engine... Show more

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A.I.Advisor
published price charts
A.I.Advisor
Nov 07, 2026

Why Cardio Diagnostics Holdings (CDIO) Stock Is Down -16.8% in the Last 30 Days

Key Takeaways

  • Cardio Diagnostics Holdings (CDIO) fell about 16.8% over the past 30 days, sliding from a close of $1.97 on October 7, 2026, to $1.64 on November 6, 2026.
  • The decline was gradual rather than driven by a single headline event, unfolding across a stretch of light and uneven trading volume typical of a micro-cap stock.
  • Over the trailing three months, shares are roughly flat—down about 3%—reflecting elevated volatility after a sharp mid-August spike that quickly faded.
  • Cardio Diagnostics is a Chicago-based molecular diagnostics company with a market capitalization near $5 million, modest revenue, and ongoing net losses as it commercializes its cardiovascular tests.
  • Investors are watching the rollout of its Epi+Gen CHD and PrecisionCHD blood tests, its newly launched in-house CLIA-certified laboratory, and payer coverage agreements.
  • The company is expected to report third-quarter financial results in November 2026, a key event for near-term sentiment.
  • For more detail on this ticker, explore its Price Targets, Earnings, and Forecast pages.
  • You can also monitor how automated strategies are positioning in names like this on the Trending AI Robots page.

Cardio Diagnostics Holdings (CDIO) Company Overview and Market Position

Cardio Diagnostics Holdings, Inc. is a molecular diagnostics company focused on the detection and risk assessment of cardiovascular disease. Founded in 2017 and headquartered in Chicago, Illinois, the company develops epigenetics-based and AI-driven blood tests that assess risk for coronary heart disease events, including heart attacks. Its flagship products are Epi+Gen CHD, a three-year symptomatic coronary heart disease risk assessment test, and PrecisionCHD, an integrated epigenetic-genetic test for detecting coronary heart disease.

The company's portfolio also includes HeartRisk, a SaaS cardiovascular risk intelligence platform, and CardioInnovate360, a research-use-only solution supporting biopharmaceutical discovery and validation. Cardio Diagnostics serves telemedicine providers, concierge practices, longevity clinics, risk-bearing provider organizations, and employers. Investors follow the stock for its potential to modernize cardiovascular risk screening, though the company remains an early-stage, thinly capitalized player competing against larger, better-funded diagnostics and medical-technology firms.

Cardio Diagnostics Holdings (CDIO) Stock Price Performance: Last 30 Days vs. Quarter

Over the last 30 days, CDIO moved from a closing price of $1.97 on October 7, 2026, to $1.64 on November 6, 2026—a decline of approximately 16.8%. The move lower was not a single-session shock but a steady drift punctuated by brief bounces, with daily closes progressively stepping down through the second half of October and into early November.

Zooming out to the trailing three months paints a more muted picture. From a close of $1.69 in early August 2026 to $1.64 in early November, the stock is down only about 3%. That relatively flat quarterly result masks significant intra-quarter volatility: shares spiked to intraday highs above $2.20 in mid-August on a surge in volume before retracing, and then consolidated in a $1.85–$2.15 range through September before the recent leg lower. The net effect is a high-volatility, lower-liquidity name that has given back its earlier gains.

What Drove CDIO Stock Price in the Last 30 Days

The 30-day decline in CDIO does not trace to a single, widely reported catalyst. Instead, the move reflects the mechanics of a micro-cap stock with a market capitalization near $5 million and average daily volume in the tens of thousands of shares. With limited institutional sponsorship and thin order books, relatively small amounts of selling pressure can translate into outsized percentage moves.

Context matters here. The stock had posted a sharp rally in mid-August and held elevated levels into late September, leaving room for profit-taking once momentum stalled. As broader risk appetite cooled and the stock drifted below short-term support levels in the $1.80–$1.90 area, the pullback fed on itself in the absence of fresh, positive company-specific news. Ongoing concerns about the pace of commercialization, minimal reported revenue, and continuing cash burn likely also weighed on sentiment as investors awaited the next quarterly update.

What Drove CDIO Stock Performance Over the Last Quarter

The broader three-month narrative is one of a short-lived enthusiasm spike followed by normalization. In August, Cardio Diagnostics hosted an investor conference call and continued to build out its commercial infrastructure, most notably advancing toward full in-house test processing at a high-complexity, CLIA-certified laboratory in Iowa City. That operational milestone gives the company greater end-to-end control over its testing workflow and is central to its scaling strategy.

At the same time, the company has worked to expand access to its tests, including payer coverage arrangements with provider networks such as Atlas Healthcare Physicians, and has continued publishing research and reports on rural cardiovascular care. Despite these steps, the stock's quarterly performance underscores that early-stage commercialization has yet to translate into meaningful revenue growth, keeping the share price sensitive to liquidity, sentiment, and execution headlines rather than fundamentals alone.

Trending AI Robots

Tickeron's Trending AI Robots page highlights a curated selection of automated trading strategies from a platform that offers hundreds of AI-driven bots trading across thousands of tickers. Rather than listing every available bot, the section surfaces only the top-performing and most relevant strategies, helping users cut through the noise. The bots differ meaningfully in their trading approach, holding timeframe, and performance metrics, so no single strategy fits every investor. For those interested in how algorithmic systems are approaching names like CDIO and the broader market, exploring the page offers a practical starting point.

CDIO Stock Forecast Drivers: What Investors Should Watch Next

Looking ahead, the most important near-term catalyst is the company's third-quarter 2026 earnings report and management commentary, expected in November 2026. Investors will focus on revenue progression, cash position, operating expenses, and any updates on test volume and reimbursement. Given the firm's modest top-line figures and ongoing net losses, clarity on the path toward commercialization and reduced cash burn will be central to the outlook.

Beyond earnings, watch for progress on payer coverage expansion, utilization of the new in-house CLIA laboratory, and any new distribution or provider partnerships. Macroeconomic factors, including access to capital for early-stage healthcare companies and general risk appetite, also matter for a micro-cap name with limited liquidity. As always, the figures and events referenced here are subject to change, and investors should consult primary filings and disclosures before drawing conclusions.

Disclaimer

The information on this webpage is provided for general informational and educational purposes only and is not intended as investment advice, a recommendation to purchase or sell any security, or an offer or solicitation related to investments. It does not consider your personal financial situation, goals, or risk profile, and all investing carries inherent risks, including the possibility of losing your entire investment. For more details, please review our full disclaimer.

Disclaimers and Limitations

A.I.Advisor
a Summary for CDIO with price predictions
Nov 11, 2026

CDIO in upward trend: price rose above 50-day moving average on November 10, 2026

CDIO moved above its 50-day moving average on November 10, 2026 date and that indicates a change from a downward trend to an upward trend. In 22 of 24 similar past instances, the stock price increased further within the following month. The odds of a continued upward trend are 90%.

Price Prediction Chart

Technical Analysis (Indicators)

Bullish Trend Analysis

The RSI Oscillator points to a transition from a downward trend to an upward trend -- in cases where CDIO's RSI Oscillator exited the oversold zone, 44 of 50 resulted in an increase in price. Tickeron's analysis proposes that the odds of a continued upward trend are 88%.

The Momentum Indicator moved above the 0 level on November 09, 2026. You may want to consider a long position or call options on CDIO as a result. In 45 of 64 past instances where the momentum indicator moved above 0, the stock continued to climb. The odds of a continued upward trend are 70%.

The Moving Average Convergence Divergence (MACD) for CDIO just turned positive on November 06, 2026. Looking at past instances where CDIO's MACD turned positive, the stock continued to rise in 24 of 38 cases over the following month. The odds of a continued upward trend are 63%.

Following a +6.67% 3-day Advance, the price is estimated to grow further. Considering data from situations where CDIO advanced for three days, in 113 of 154 cases, the price rose further within the following month. The odds of a continued upward trend are 73%.

The Aroon Indicator entered an Uptrend today. In 53 of 136 cases where CDIO Aroon's Indicator entered an Uptrend, the price rose further within the following month. The odds of a continued Uptrend are 39%.

Bearish Trend Analysis

The Stochastic Oscillator entered the overbought zone. Expect a price pull-back in the foreseeable future.

The 10-day moving average for CDIO crossed bearishly below the 50-day moving average on October 12, 2026. This indicates that the trend has shifted lower and could be considered a sell signal. In 9 of 9 past instances when the 10-day crossed below the 50-day, the stock continued to move higher over the following month. The odds of a continued downward trend are 90%.

Following a 3-day decline, the stock is projected to fall further. Considering past instances where CDIO declined for three days, the price rose further in 50 of 62 cases within the following month. The odds of a continued downward trend are 90%.

CDIO broke above its upper Bollinger Band on November 10, 2026. This could be a sign that the stock is set to drop as the stock moves back below the upper band and toward the middle band. You may want to consider selling the stock or exploring put options.

Fundamental Analysis (Ratings)

The Tickeron PE Growth Rating for this company is 45 (best 1 - 100 worst), pointing to average earnings growth. The PE Growth rating is based on a comparative analysis of stock PE ratio increase over the last 12 months compared against S&P 500 index constituents.

The Tickeron Price Growth Rating for this company is 61 (best 1 - 100 worst), indicating steady price growth. CDIO’s price grows at a higher rate over the last 12 months as compared to S&P 500 index constituents.

The Tickeron Valuation Rating of 70 (best 1 - 100 worst) indicates that the company is slightly overvalued in the industry. This rating compares market capitalization estimated by our proprietary formula with the current market capitalization. This rating is based on the following metrics, as compared to industry averages: P/B Ratio (0.654) is normal, around the industry mean (3.498). P/E Ratio (-0.566) is within average values for comparable stocks, (-1.193). Projected Growth (PEG Ratio) (0.000) is also within normal values, averaging (9.059). Dividend Yield (0.000) settles around the average of (130.981) among similar stocks. P/S Ratio (322.581) is also within normal values, averaging (440.869).

The Tickeron SMR rating for this company is 98 (best 1 - 100 worst), indicating weak sales and an unprofitable business model. SMR (Sales, Margin, Return on Equity) rating is based on comparative analysis of weighted Sales, Income Margin and Return on Equity values compared against S&P 500 index constituents. The weighted SMR value is a proprietary formula developed by Tickeron and represents an overall profitability measure for a stock.

The Tickeron Profit vs. Risk Rating rating for this company is 100 (best 1 - 100 worst), indicating that the returns do not compensate for the risks. CDIO’s unstable profits reported over time resulted in significant Drawdowns within these last five years. A stable profit reduces stock drawdown and volatility. The average Profit vs. Risk Rating rating for the industry is 93, placing this stock worse than average.

A.I.Advisor
published Highlights

Notable companies

The most notable companies in this group are Moderna (NASDAQ:MRNA), Regeneron Pharmaceuticals (NASDAQ:REGN), Incyte Corp (NASDAQ:INCY), Exelixis (NASDAQ:EXEL), Arrowhead Pharmaceuticals (NASDAQ:ARWR), Sarepta Therapeutics (NASDAQ:SRPT), Novavax (NASDAQ:NVAX), Nektar Therapeutics (NASDAQ:NKTR), Inovio Pharmaceuticals (NASDAQ:INO), Cel-Sci Corp (ASE:CVM).

Industry description

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

Market Cap

The average market capitalization across the Biotechnology Industry is 2.23B. The market cap for tickers in the group ranges from 58 to 138.67B. VRTX holds the highest valuation in this group at 138.67B. The lowest valued company is SEELQ at 58.

High and low price notable news

The average weekly price growth across all stocks in the Biotechnology Industry was -0%. For the same Industry, the average monthly price growth was -7%, and the average quarterly price growth was -14%. PEPG experienced the highest price growth at 115%, while KPTI experienced the biggest fall at -76%.

Volume

The average weekly volume growth across all stocks in the Biotechnology Industry was -22%. For the same stocks of the Industry, the average monthly volume growth was 23% and the average quarterly volume growth was -37%

Fundamental Analysis Ratings

The average fundamental analysis ratings, where 1 is best and 100 is worst, are as follows

Valuation Rating: 50
P/E Growth Rating: 43
Price Growth Rating: 66
SMR Rating: 93
Profit Risk Rating: 93
Seasonality Score: -4 (-100 ... +100)