Cardiol Therapeutics Inc is a late-stage life sciences company focused on advancing the development of anti-inflammatory and anti-fibrotic therapies for heart disease... Show more
Cardiol Therapeutics Inc. (CRDL) is a clinical-stage life sciences company focused on developing anti-inflammatory and anti-fibrotic therapies for heart diseases. Its lead candidate, CardiolRx™, a proprietary oral cannabidiol formulation, targets inflammasome pathway activation implicated in conditions like recurrent pericarditis and acute myocarditis. The company also advances CRD-38, a subcutaneous injection for heart failure in preclinical stages.
Operating in the competitive cardiovascular biotech sector, Cardiol differentiates through its novel immunomodulatory approach to underserved rare cardiac indications. With Phase III MAVERIC trial underway and positive Phase II ARCHER data, its pipeline progress explains recent stock resilience amid biotech volatility, highlighting strong fundamentals in high-unmet-need areas.
Over the last 30 days, CRDL stock climbed from approximately $0.97 (March 6 close) to $1.35 (April 7 close), marking a +39% gain. The movement was volatile yet trend-driven, with sharp rallies around March 26-31 (+22% in days) tied to earnings and trial news, followed by consolidation near $1.35-$1.41.
For the quarter, shares advanced +34% from $1.01 (January 7 close) to $1.35, reflecting steady uptrend punctuated by dips in early March before late-month surge. Trading volume spiked on catalysts, with 52-week range $0.77-$1.59 underscoring upward momentum.
The 30-day rally stemmed primarily from robust Q4 2025 earnings on March 30-31, where EPS of -$0.05 beat estimates of -$0.09 by 44%, narrowing losses and affirming operational execution. Year-end update highlighted full funding for MAVERIC trial via $31M raised, extending runway to Q4 2027.
Positive sentiment amplified by ARCHER Phase II publication in ESC Heart Failure (early April context), showing significant left ventricular mass reduction (-9.2g, p=0.0117) in acute myocarditis, validating CardiolRx™ efficacy. Analyst reiterations like HC Wainwright's Buy/$9 target and Canaccord's Buy/$8 fueled buying. Biotech sector tailwinds on inflammation therapies further supported the volatile upswing.
The quarterly +34% gain built on sustained clinical momentum, starting with January 16 bought-deal financing announcement ($13.5M gross, closed $14.85M January 23), bolstering balance sheet post-October 2025 private placement. January 13 MAVERIC Phase III hit 50% enrollment (target ~110 patients across 25+ sites), signaling pivotal progress in recurrent pericarditis.
February 10 ARCHER topline reinforced with ESC publication, linking to MAVERIC via shared mechanisms. Macro biotech recovery, favorable interest rates, and institutional interest in orphan cardiac drugs amplified impact. Cumulative financing and milestones reduced dilution fears, driving outperformance versus broader indices.
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Investors should monitor MAVERIC Phase III enrollment completion (expected Q2 2026) and topline data timeline toward NDA submission. Upcoming Q1 earnings (est. May 2026) will detail burn rate post-financing. ARCHER full dataset and potential expansion to heart failure via CRD-38 IND filing are key.
Industry trends in anti-inflammatory cardio therapies, FDA feedback on orphan status, and analyst updates amid biotech M&A activity warrant attention. Macro factors like interest rates impacting funding and sector sentiment, plus risks from trial delays or dilution, remain critical for price movement outlook.
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The 50-day moving average for CRDL moved above the 200-day moving average on April 16, 2026. This could be a long-term bullish signal for the stock as the stock shifts to an upward trend.
Following a 3-day Advance, the price is estimated to grow further. Considering data from situations where CRDL advanced for three days, in of 224 cases, the price rose further within the following month. The odds of a continued upward trend are .
The Aroon Indicator entered an Uptrend today. In of 145 cases where CRDL Aroon's Indicator entered an Uptrend, the price rose further within the following month. The odds of a continued Uptrend are .
The 10-day RSI Indicator for CRDL moved out of overbought territory on April 22, 2026. This could be a bearish sign for the stock. Traders may want to consider selling the stock or buying put options. Tickeron's A.I.dvisor looked at 36 similar instances where the indicator moved out of overbought territory. In of the 36 cases, the stock moved lower in the following days. This puts the odds of a move lower at .
The Stochastic Oscillator may be shifting from an upward trend to a downward trend. In of 59 cases where CRDL's Stochastic Oscillator exited the overbought zone, the price fell further within the following month. The odds of a continued downward trend are .
The Momentum Indicator moved below the 0 level on May 14, 2026. You may want to consider selling the stock, shorting the stock, or exploring put options on CRDL as a result. In of 100 cases where the Momentum Indicator fell below 0, the stock fell further within the subsequent month. The odds of a continued downward trend are .
The Moving Average Convergence Divergence Histogram (MACD) for CRDL turned negative on April 23, 2026. This could be a sign that the stock is set to turn lower in the coming weeks. Traders may want to sell the stock or buy put options. Tickeron's A.I.dvisor looked at 53 similar instances when the indicator turned negative. In of the 53 cases the stock turned lower in the days that followed. This puts the odds of success at .
Following a 3-day decline, the stock is projected to fall further. Considering past instances where CRDL declined for three days, the price rose further in of 62 cases within the following month. The odds of a continued downward trend are .
CRDL broke above its upper Bollinger Band on April 21, 2026. This could be a sign that the stock is set to drop as the stock moves back below the upper band and toward the middle band. You may want to consider selling the stock or exploring put options.
The Tickeron Price Growth Rating for this company is (best 1 - 100 worst), indicating steady price growth. CRDL’s price grows at a higher rate over the last 12 months as compared to S&P 500 index constituents.
The Tickeron Valuation Rating of (best 1 - 100 worst) indicates that the company is fair valued in the industry. This rating compares market capitalization estimated by our proprietary formula with the current market capitalization. This rating is based on the following metrics, as compared to industry averages: P/B Ratio (8.651) is normal, around the industry mean (65.142). P/E Ratio (0.000) is within average values for comparable stocks, (60.387). CRDL's Projected Growth (PEG Ratio) (0.000) is slightly lower than the industry average of (1.985). CRDL has a moderately low Dividend Yield (0.000) as compared to the industry average of (0.030). P/S Ratio (0.000) is also within normal values, averaging (109.366).
The Tickeron PE Growth Rating for this company is (best 1 - 100 worst), pointing to worse than average earnings growth. The PE Growth rating is based on a comparative analysis of stock PE ratio increase over the last 12 months compared against S&P 500 index constituents.
The Tickeron SMR rating for this company is (best 1 - 100 worst), indicating weak sales and an unprofitable business model. SMR (Sales, Margin, Return on Equity) rating is based on comparative analysis of weighted Sales, Income Margin and Return on Equity values compared against S&P 500 index constituents. The weighted SMR value is a proprietary formula developed by Tickeron and represents an overall profitability measure for a stock.
The Tickeron Profit vs. Risk Rating rating for this company is (best 1 - 100 worst), indicating that the returns do not compensate for the risks. CRDL’s unstable profits reported over time resulted in significant Drawdowns within these last five years. A stable profit reduces stock drawdown and volatility. The average Profit vs. Risk Rating rating for the industry is 90, placing this stock worse than average.
The average fundamental analysis ratings, where 1 is best and 100 is worst, are as follows
Industry PharmaceuticalsGeneric