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INO stock forecast, quote, news & analysis

Inovio Pharmaceuticals Inc is a clinical-stage biotechnology company focused on developing and commercializing DNA medicines to help treat and protect people from diseases associated with human papillomavirus (HPV), cancer and infectious diseases... Show more

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Sep 03, 2026

Why Inovio Pharmaceuticals (INO) Stock Is Up +105% in the Last 30 Days

Key Takeaways

  • INO shares climbed roughly 105% over the past 30 days, rising from about $0.66 to around $1.36.
  • The rebound followed a sharp late-July selloff tied to a $20 million equity offering that diluted existing shareholders.
  • Investor attention remains centered on the FDA decision for lead candidate INO-3107 in recurrent respiratory papillomatosis (RRP), with a PDUFA target action date of October 30, 2026.
  • Second-quarter 2026 results showed a narrower net loss of $0.07 per share, and Jefferies upgraded the stock to Buy with a $3.00 price target.
  • The stock remains highly volatile and well below its 52-week high, reflecting binary event risk ahead of the FDA decision.

Inovio Pharmaceuticals (INO) Company Overview and Market Position

Inovio Pharmaceuticals is a clinical-stage biotechnology company developing DNA medicines designed to treat and protect people from HPV-related diseases, cancer, and infectious diseases. Its platform combines precisely designed DNA plasmids with a proprietary electroporation delivery device called CELLECTRA, which is intended to deliver genetic material into cells without viral vectors or lipid nanoparticles.

The company's lead program, INO-3107, is an investigational DNA immunotherapy for recurrent respiratory papillomatosis, a rare and chronic condition caused by HPV types 6 and 11. Inovio is also advancing VGX-3100 for HPV-related cervical dysplasia, which has been licensed to ApolloBio for Greater China, as well as next-generation DNA-encoded monoclonal antibody and DNA-encoded protein programs. With no approved commercial products yet, the stock is closely watched as a binary, event-driven bet on regulatory outcomes rather than current revenue.

Inovio Pharmaceuticals (INO) Stock Price Performance: Last 30 Days vs. Quarter

Over the last 30 days, INO shares advanced approximately 105%, moving from a closing level near $0.66 to roughly $1.36. The gain was concentrated after a late-July trough, when the stock fell to an intraday low around $0.57 before reversing sharply higher through August.

The trailing three-month picture tells a more volatile story. The stock traded near $1.14 in early June and briefly reached the low $1.20s in early July before the late-July financing announcement pushed shares to multi-year lows. The subsequent recovery leaves the stock up roughly 19% over the trailing quarter on a net basis, though that headline figure understates the intra-period swings. The stock remains well below its 52-week high of approximately $2.98.

What Drove INO Stock Price in the Last 30 Days

The dominant catalyst was the unwind and recovery of a dilution-driven selloff. On July 29, 2026, Inovio announced a $20 million public offering priced at $0.95 per share, with attached warrants. The dilutive terms triggered a sharp decline that pushed shares to around $0.656 by July 30, marking the starting point for the subsequent rebound.

The recovery was driven by a series of positive updates. On August 12, Inovio reported second-quarter 2026 results showing a net loss of $6.0 million, or $0.07 per share, a substantial improvement from $23.5 million, or $0.61 per share, in the prior-year period. Management also disclosed that the FDA had completed its late-cycle review meeting and all scheduled pre-licensure inspections for INO-3107, keeping the program on track for its October 30, 2026 PDUFA date.

Analyst sentiment added momentum. On August 13, Jefferies upgraded Inovio from Hold to Buy and raised its price target to $3.00 from $1.80, citing progress in the FDA review process. H.C. Wainwright separately reiterated a Neutral rating with a $2.50 price target. Together, these catalysts helped fuel a multi-week rally in a small-cap stock with elevated short interest and high volatility.

What Drove INO Stock Performance Over the Last Quarter

The broader quarterly narrative centers on Inovio's transition toward a potential first commercial launch. The FDA accepted the Biologics License Application for INO-3107 under the accelerated approval pathway in December 2025, setting a PDUFA target action date of October 30, 2026. Throughout the quarter, the company completed key review milestones, including pre-licensure inspections and an informal clinical meeting with the agency.

Financing activity shaped the trading pattern. The July public offering generated approximately $18.3 million in net proceeds, extending the company's projected cash runway into late first quarter 2027 and through a potential launch. While the offering pressured the stock near term, it reduced near-term liquidity risk. Pipeline news also supported sentiment, including positive Phase 3 topline results for VGX-3100 reported by partner ApolloBio in China, which validated the DNA-medicine platform for HPV-related disease.

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INO Stock Forecast Drivers: What Investors Should Watch Next

The most significant upcoming catalyst is the FDA's decision on INO-3107, with a PDUFA target action date of October 30, 2026. Key items to monitor include the agency's view on accelerated approval eligibility, feedback on the confirmatory trial design, and the outcome of label negotiations, which management indicated could begin in September.

Investors should also track commercial readiness ahead of a potential launch, including the build-out of the sales organization through Syneos Health and competitive dynamics with the already-approved RRP therapy Papzimeos. Financial factors remain important as well: the company's cash runway extends into late first quarter 2027, but further capital-raising may be required depending on launch timing and spending. Broader pipeline progress, including a potential regulatory filing for VGX-3100 in China and partnership discussions for next-generation programs, represents additional longer-term drivers.

Disclaimer

The information on this webpage is provided for general informational and educational purposes only and is not intended as investment advice, a recommendation to purchase or sell any security, or an offer or solicitation related to investments. It does not consider your personal financial situation, goals, or risk profile, and all investing carries inherent risks, including the possibility of losing your entire investment. For more details, please review our full disclaimer.

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a Summary for INO with price predictions
Sep 02, 2026

INO in upward trend: price rose above 50-day moving average on August 14, 2026

INO moved above its 50-day moving average on August 14, 2026 date and that indicates a change from a downward trend to an upward trend. In of 49 similar past instances, the stock price increased further within the following month. The odds of a continued upward trend are .

Price Prediction Chart

Technical Analysis (Indicators)

Bullish Trend Analysis

The Momentum Indicator moved above the 0 level on August 13, 2026. You may want to consider a long position or call options on INO as a result. In of 75 past instances where the momentum indicator moved above 0, the stock continued to climb. The odds of a continued upward trend are .

The Moving Average Convergence Divergence (MACD) for INO just turned positive on August 13, 2026. Looking at past instances where INO's MACD turned positive, the stock continued to rise in of 42 cases over the following month. The odds of a continued upward trend are .

The 10-day moving average for INO crossed bullishly above the 50-day moving average on August 24, 2026. This indicates that the trend has shifted higher and could be considered a buy signal. In of 17 past instances when the 10-day crossed above the 50-day, the stock continued to move higher over the following month. The odds of a continued upward trend are .

Following a 3-day Advance, the price is estimated to grow further. Considering data from situations where INO advanced for three days, in of 229 cases, the price rose further within the following month. The odds of a continued upward trend are .

The Aroon Indicator entered an Uptrend today. In of 162 cases where INO Aroon's Indicator entered an Uptrend, the price rose further within the following month. The odds of a continued Uptrend are .

Bearish Trend Analysis

The RSI Oscillator demonstrated that the stock has entered the overbought zone. This may point to a price pull-back soon.

The Stochastic Oscillator demonstrated that the ticker has stayed in the overbought zone for 13 days. The longer the ticker stays in the overbought zone, the sooner a price pull-back is expected.

Following a 3-day decline, the stock is projected to fall further. Considering past instances where INO declined for three days, the price rose further in of 62 cases within the following month. The odds of a continued downward trend are .

INO broke above its upper Bollinger Band on August 17, 2026. This could be a sign that the stock is set to drop as the stock moves back below the upper band and toward the middle band. You may want to consider selling the stock or exploring put options.

Fundamental Analysis (Ratings)

The Tickeron Price Growth Rating for this company is (best 1 - 100 worst), indicating steady price growth. INO’s price grows at a higher rate over the last 12 months as compared to S&P 500 index constituents.

The Tickeron Valuation Rating of (best 1 - 100 worst) indicates that the company is slightly overvalued in the industry. This rating compares market capitalization estimated by our proprietary formula with the current market capitalization. This rating is based on the following metrics, as compared to industry averages: P/B Ratio (32.154) is normal, around the industry mean (20.583). P/E Ratio (0.000) is within average values for comparable stocks, (27.923). Projected Growth (PEG Ratio) (0.000) is also within normal values, averaging (2.559). Dividend Yield (0.000) settles around the average of (0.018) among similar stocks. P/S Ratio (1000.000) is also within normal values, averaging (443.835).

The Tickeron PE Growth Rating for this company is (best 1 - 100 worst), pointing to worse than average earnings growth. The PE Growth rating is based on a comparative analysis of stock PE ratio increase over the last 12 months compared against S&P 500 index constituents.

The Tickeron SMR rating for this company is (best 1 - 100 worst), indicating weak sales and an unprofitable business model. SMR (Sales, Margin, Return on Equity) rating is based on comparative analysis of weighted Sales, Income Margin and Return on Equity values compared against S&P 500 index constituents. The weighted SMR value is a proprietary formula developed by Tickeron and represents an overall profitability measure for a stock.

The Tickeron Profit vs. Risk Rating rating for this company is (best 1 - 100 worst), indicating that the returns do not compensate for the risks. INO’s unstable profits reported over time resulted in significant Drawdowns within these last five years. A stable profit reduces stock drawdown and volatility. The average Profit vs. Risk Rating rating for the industry is 92, placing this stock worse than average.

A.I.Advisor
published Highlights

Notable companies

The most notable companies in this group are Regeneron Pharmaceuticals (NASDAQ:REGN), Moderna (NASDAQ:MRNA), Incyte Corp (NASDAQ:INCY), Exelixis (NASDAQ:EXEL), Arrowhead Pharmaceuticals (NASDAQ:ARWR), Nektar Therapeutics (NASDAQ:NKTR), Sarepta Therapeutics (NASDAQ:SRPT), Novavax (NASDAQ:NVAX), Inovio Pharmaceuticals (NASDAQ:INO), Cel-Sci Corp (ASE:CVM).

Industry description

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

Market Cap

The average market capitalization across the Biotechnology Industry is 2.34B. The market cap for tickers in the group ranges from 58 to 141.11B. VRTX holds the highest valuation in this group at 141.11B. The lowest valued company is SEELQ at 58.

High and low price notable news

The average weekly price growth across all stocks in the Biotechnology Industry was -3%. For the same Industry, the average monthly price growth was 5%, and the average quarterly price growth was 2,204%. CELU experienced the highest price growth at 111%, while VBIO experienced the biggest fall at -97%.

Volume

The average weekly volume growth across all stocks in the Biotechnology Industry was 21%. For the same stocks of the Industry, the average monthly volume growth was 9% and the average quarterly volume growth was 19%

Fundamental Analysis Ratings

The average fundamental analysis ratings, where 1 is best and 100 is worst, are as follows

Valuation Rating: 50
P/E Growth Rating: 78
Price Growth Rating: 53
SMR Rating: 94
Profit Risk Rating: 92
Seasonality Score: -10 (-100 ... +100)
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published General Information

General Information

a developer of synthetic vaccines and immune therapies for cancers and infectious diseases

Industry Biotechnology

Profile
Details
Industry
Medical Specialties
Address
660 West Germantown Pike
Phone
+1 267 440-4200
Employees
112
Web
https://www.inovio.com
Why Inovio Pharmaceuticals (INO) Stock Is Up +105% in the Last 30 Days