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STRO stock forecast, quote, news & analysis

Sutro Biopharma Inc is a clinical-stage drug discovery, development, and manufacturing company... Show more

STRO
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Why Sutro Biopharma (STRO) Is Up +67% in the Last 30 Days

Key Takeaways

  • Sutro Biopharma (STRO) stock surged +67% over the last 30 days, driven by positive preclinical data presentations and ongoing clinical advancements in its antibody drug conjugate (ADC) pipeline.
  • Over the past quarter, shares climbed +119%, fueled by a $110 million public offering, full-year 2025 earnings release highlighting strong cash position, and key trial initiations.
  • Biotech sector momentum in ADCs, institutional interest, and promising Phase 1 dosing for lead candidate STRO-004 supported the upward price movement.
  • Recent volatility showed steady uptrend with increased trading volume around earnings and conference updates.
  • 52-week range expanded to $5.30-$34.58 following a 1-for-10 reverse stock split in December 2025.

Sutro Biopharma (STRO) Company Overview and Market Position

Sutro Biopharma, Inc. (STRO) is a clinical-stage oncology company specializing in the discovery, development, and manufacturing of next-generation antibody drug conjugates (ADCs). Leveraging its proprietary cell-free protein synthesis platform, XpressCF, and site-specific conjugation technology, XpressCF+, the company designs precision therapeutics for cancer and autoimmune diseases. Its pipeline includes STRO-004, targeting tissue factor (TF) in solid tumors, and STRO-003, directed against ROR1 for various cancers. Partnerships with Vaxcyte, Ipsen, Astellas, and others bolster its position in the competitive ADC market, dominated by players like Seagen and Pfizer. Strong fundamentals in innovative manufacturing expose STRO to biotech rallies, explaining recent stock price gains amid pipeline progress.

Sutro Biopharma (STRO) Stock Price Performance: Last 30 Days vs. Quarter

Over the last 30 days, STRO stock rose from approximately $20.68 to $34.58, marking a +67% gain. The movement was trend-driven with volatility, featuring sharp increases post-earnings and conference data, alongside elevated volume.

In the past quarter, shares advanced from around $15.80 to $34.58, delivering a +119% return. Performance was steadily upward, punctuated by funding announcements and clinical milestones, reflecting range expansion from prior lows.

What Drove STRO Stock Price in the Last 30 Days

The 30-day rally gained momentum following the March 23 full-year 2025 earnings release, which reported $102.5 million in revenue and a $141.4 million cash position as of year-end, exceeding some expectations and signaling financial stability. Preclinical data presented at the American Association for Cancer Research (AACR) annual meeting highlighted efficacy across STRO's ADC programs, boosting investor sentiment in the hot ADC space. Initiation of Phase 1 dosing for STRO-004 in TF-expressing solid tumors further catalyzed gains, with shares surging 7.4% in early April amid heightened volume. Positive analyst commentary and sector tailwinds in oncology biotech contributed to the steady climb, connecting directly to pipeline validation.

What Drove STRO Stock Performance Over the Last Quarter

The quarterly surge built on broader narratives, including a $110 million public offering in February that priced shares higher and improved liquidity, sparking an 11.9% single-day jump. Full-year earnings underscored revenue growth from collaborations and preserved runway into 2027, countering cash burn concerns common in clinical-stage biotechs. Industry developments in ADCs, regulatory clearances like the U.S. FDA IND for new programs, and macroeconomic easing in interest rates favored growth-oriented biotech stocks. Institutional accumulation and competitive positioning via proprietary platforms amplified cumulative impact, driving sustained outperformance versus broader indices.

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STRO Stock Forecast Drivers: What Investors Should Watch Next

Investors should monitor upcoming Q1 2026 earnings for revenue updates from partnerships and cash burn trends. Clinical readouts from Phase 1 trials of STRO-004 and STRO-003, including safety and efficacy data, could sway sentiment. Broader ADC market trends, competitor milestones, and macroeconomic factors like interest rates impacting biotech funding remain key. Strategic developments such as new collaborations or IND clearances, alongside regulatory feedback, present potential catalysts or risks in this pipeline-dependent story.

Disclaimer

The information on this webpage is provided for general informational and educational purposes only and is not intended as investment advice, a recommendation to purchase or sell any security, or an offer or solicitation related to investments. It does not consider your personal financial situation, goals, or risk profile, and all investing carries inherent risks, including the possibility of losing your entire investment. For more details, please review our full disclaimer. Disclaimers and Limitations

A.I.Advisor
a Summary for STRO with price predictions
Jun 22, 2026

Aroon Indicator for STRO shows an upward move is likely

STRO's Aroon Indicator triggered a bullish signal on May 21, 2026. Tickeron's A.I.dvisor detected that the AroonUp green line is above 70 while the AroonDown red line is below 30. When the up indicator moves above 70 and the down indicator remains below 30, it is a sign that the stock could be setting up for a bullish move. Traders may want to buy the stock or look to buy calls options. A.I.dvisor looked at 144 similar instances where the Aroon Indicator showed a similar pattern. In of the 144 cases, the stock moved higher in the days that followed. This puts the odds of a move higher at .

Price Prediction Chart

Technical Analysis (Indicators)

Bullish Trend Analysis

The RSI Oscillator points to a transition from a downward trend to an upward trend -- in cases where STRO's RSI Oscillator exited the oversold zone, of 48 resulted in an increase in price. Tickeron's analysis proposes that the odds of a continued upward trend are .

The Momentum Indicator moved above the 0 level on June 15, 2026. You may want to consider a long position or call options on STRO as a result. In of 84 past instances where the momentum indicator moved above 0, the stock continued to climb. The odds of a continued upward trend are .

The Moving Average Convergence Divergence (MACD) for STRO just turned positive on June 15, 2026. Looking at past instances where STRO's MACD turned positive, the stock continued to rise in of 43 cases over the following month. The odds of a continued upward trend are .

Following a +1 3-day Advance, the price is estimated to grow further. Considering data from situations where STRO advanced for three days, in of 252 cases, the price rose further within the following month. The odds of a continued upward trend are .

STRO may jump back above the lower band and head toward the middle band. Traders may consider buying the stock or exploring call options.

Bearish Trend Analysis

The Stochastic Oscillator entered the overbought zone. Expect a price pull-back in the foreseeable future.

STRO moved below its 50-day moving average on May 22, 2026 date and that indicates a change from an upward trend to a downward trend.

The 10-day moving average for STRO crossed bearishly below the 50-day moving average on June 01, 2026. This indicates that the trend has shifted lower and could be considered a sell signal. In of 19 past instances when the 10-day crossed below the 50-day, the stock continued to move higher over the following month. The odds of a continued downward trend are .

Following a 3-day decline, the stock is projected to fall further. Considering past instances where STRO declined for three days, the price rose further in of 62 cases within the following month. The odds of a continued downward trend are .

Fundamental Analysis (Ratings)

The Tickeron Valuation Rating of (best 1 - 100 worst) indicates that the company is slightly undervalued in the industry. This rating compares market capitalization estimated by our proprietary formula with the current market capitalization. This rating is based on the following metrics, as compared to industry averages: P/B Ratio (1.785) is normal, around the industry mean (20.966). P/E Ratio (0.000) is within average values for comparable stocks, (36.007). Projected Growth (PEG Ratio) (0.000) is also within normal values, averaging (1.690). STRO has a moderately low Dividend Yield (0.000) as compared to the industry average of (0.038). P/S Ratio (3.066) is also within normal values, averaging (367.026).

The Tickeron Price Growth Rating for this company is (best 1 - 100 worst), indicating steady price growth. STRO’s price grows at a higher rate over the last 12 months as compared to S&P 500 index constituents.

The Tickeron Seasonality Score of (best 1 - 100 worst) indicates that the company is significantly overvalued in the industry. The Tickeron Seasonality score describes the variance of predictable price changes around the same period every calendar year. These changes can be tied to a specific month, quarter, holiday or vacation period, as well as a meteorological or growing season.

The Tickeron PE Growth Rating for this company is (best 1 - 100 worst), pointing to worse than average earnings growth. The PE Growth rating is based on a comparative analysis of stock PE ratio increase over the last 12 months compared against S&P 500 index constituents.

The Tickeron SMR rating for this company is (best 1 - 100 worst), indicating weak sales and an unprofitable business model. SMR (Sales, Margin, Return on Equity) rating is based on comparative analysis of weighted Sales, Income Margin and Return on Equity values compared against S&P 500 index constituents. The weighted SMR value is a proprietary formula developed by Tickeron and represents an overall profitability measure for a stock.

The Tickeron Profit vs. Risk Rating rating for this company is (best 1 - 100 worst), indicating that the returns do not compensate for the risks. STRO’s unstable profits reported over time resulted in significant Drawdowns within these last five years. A stable profit reduces stock drawdown and volatility. The average Profit vs. Risk Rating rating for the industry is 93, placing this stock worse than average.

A.I.Advisor
published Highlights

Notable companies

The most notable companies in this group are Regeneron Pharmaceuticals (NASDAQ:REGN), Moderna (NASDAQ:MRNA), Incyte Corp (NASDAQ:INCY), Exelixis (NASDAQ:EXEL), Arrowhead Pharmaceuticals (NASDAQ:ARWR), Nektar Therapeutics (NASDAQ:NKTR), Sarepta Therapeutics (NASDAQ:SRPT), Novavax (NASDAQ:NVAX), Inovio Pharmaceuticals (NASDAQ:INO), Cel-Sci Corp (ASE:CVM).

Industry description

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

Market Cap

The average market capitalization across the Biotechnology Industry is 2B. The market cap for tickers in the group ranges from 58 to 118.47B. VRTX holds the highest valuation in this group at 118.47B. The lowest valued company is SEELQ at 58.

High and low price notable news

The average weekly price growth across all stocks in the Biotechnology Industry was 6%. For the same Industry, the average monthly price growth was 2%, and the average quarterly price growth was 1,952%. CDT experienced the highest price growth at 111%, while VRXA experienced the biggest fall at -81%.

Volume

The average weekly volume growth across all stocks in the Biotechnology Industry was 57%. For the same stocks of the Industry, the average monthly volume growth was 51% and the average quarterly volume growth was 202%

Fundamental Analysis Ratings

The average fundamental analysis ratings, where 1 is best and 100 is worst, are as follows

Valuation Rating: 50
P/E Growth Rating: 81
Price Growth Rating: 56
SMR Rating: 94
Profit Risk Rating: 93
Seasonality Score: 16 (-100 ... +100)
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published General Information

General Information

a developer of new products in protein vaccines and therapeutics

Industry Biotechnology

Profile
Details
Industry
Pharmaceuticals Major
Address
111 Oyster Point Boulevard
Phone
+1 650 881-6500
Employees
137
Web
https://www.sutrobio.com
Why Sutro Biopharma (STRO) Is Up +67% in the Last 30 Days