Passage Bio, Inc. is a Philadelphia-based clinical-stage genetic medicines company incorporated in 2017. Historically, the company focused on developing one-time, adeno-associated virus (AAV)-based gene therapies for rare, monogenic central nervous system disorders. Its lead program, PBFT02, is an AAV1-delivered gene therapy designed to elevate progranulin levels for the treatment of frontotemporal dementia caused by GRN mutations (FTD-GRN). Passage Bio also previously advanced pediatric programs targeting GM1 gangliosidosis and Krabbe disease, which have since been out-licensed to GEMMA Biotherapeutics.
Investors follow the stock primarily for its strategic transformation. In 2026, Passage Bio agreed to an all-stock merger with Remix Therapeutics, a privately held company built on a platform that reprograms RNA processing. Remix's lead candidate, REM-422, is an oral mRNA degrader targeting the oncogenic transcription factor MYB, with clinical programs in adenoid cystic carcinoma and acute myeloid leukemia/high-risk myelodysplastic syndromes. Upon closing, the combined company is expected to operate as Remix Therapeutics, with existing Passage Bio stockholders holding a small minority stake of roughly 6%.
Over the last 30 days, PASG climbed approximately 18.9%, rising from a closing price of $3.50 on October 16, 2026, to $4.16 on November 13, 2026. The advance was not linear: the stock touched a low near $3.33 in late October before turning higher as merger milestones came into focus. I also checked this using Tickeron’s AI Screener to see how the stock compares to others in the industry.
The broader quarterly picture is more mixed. From a closing level of about $4.59 in mid-August, the stock declined roughly 9% through mid-November. That period featured significant volatility, including a rally toward $5.00 in September, a sharp selloff through October, and the November rebound. The net result highlights how strategic uncertainty weighed on shares before the recent recovery.
The recent advance was driven primarily by progress on the Remix Therapeutics merger and by improving financial results. On November 5, 2026, Passage Bio stockholders approved the merger-related proposals, including the issuance of shares representing a change of control, a reverse stock split ranging from 1-for-2 to 1-for-10, and a charter amendment to rename the company Remix Therapeutics, Inc. That approval removed a key uncertainty surrounding deal completion.
On November 10, 2026, the company reported third-quarter results showing a narrowed net loss of $4.7 million, down from $7.7 million in the prior-year period, alongside reduced operating expenses. Management reaffirmed the expectation that the merger would close in the fourth quarter of 2026 and noted the concurrent financing of approximately $100 million in gross proceeds. These developments helped restore investor confidence and supported the stock's climb from its late-October lows.
The quarterly trend reflects a fundamental strategic pivot. After winding down its gene therapy programs, Passage Bio announced the Remix Therapeutics merger in June 2026 and amended the agreement terms in September. While the deal offers a path to a well-funded RNA therapeutics platform, it also implies substantial dilution for existing holders, who are expected to own only a small percentage of the combined company. That dilution, combined with the company's reduced pipeline activity and thin cash balance of $20.2 million at September 30, 2026, pressured the stock through October. The November rebound suggests investors have begun pricing in deal completion and the combined entity's projected cash runway into 2028.
The most important near-term catalyst is the completion of the Remix Therapeutics merger, expected in the fourth quarter of 2026, along with the finalization of the concurrent financing and the associated reverse stock split. Investors should also monitor clinical data readouts for REM-422 across its oncology indications, as well as the combined company's cash position and stated runway into 2028. Additional factors to watch include the outcome of any regulatory milestones, competitive developments in RNA-targeting oncology, and broader sentiment across small-cap and clinical-stage biotechnology names. These events carry meaningful execution and scientific risk, and investors should evaluate them within the context of their own objectives and risk tolerance. From what I see, this is important because timing around these catalysts can shift sentiment quickly.
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PASG moved above its 50-day moving average on November 13, 2026 date and that indicates a change from a downward trend to an upward trend. In 31 of 35 similar past instances, the stock price increased further within the following month. The odds of a continued upward trend are 89%.
The RSI Indicator points to a transition from a downward trend to an upward trend -- in cases where PASG's RSI Indicator exited the oversold zone, 28 of 35 resulted in an increase in price. Tickeron's analysis proposes that the odds of a continued upward trend are 80%.
The Momentum Indicator moved above the 0 level on November 06, 2026. You may want to consider a long position or call options on PASG as a result. In 87 of 103 past instances where the momentum indicator moved above 0, the stock continued to climb. The odds of a continued upward trend are 84%.
The Moving Average Convergence Divergence (MACD) for PASG just turned positive on October 29, 2026. Looking at past instances where PASG's MACD turned positive, the stock continued to rise in 42 of 48 cases over the following month. The odds of a continued upward trend are 88%.
Following a +4.00% 3-day Advance, the price is estimated to grow further. Considering data from situations where PASG advanced for three days, in 172 of 212 cases, the price rose further within the following month. The odds of a continued upward trend are 81%.
The Stochastic Oscillator has been in the overbought zone for 1 day. Expect a price pull-back in the near future.
Following a 3-day decline, the stock is projected to fall further. Considering past instances where PASG declined for three days, the price rose further in 50 of 62 cases within the following month. The odds of a continued downward trend are 89%.
PASG broke above its upper Bollinger Band on November 11, 2026. This could be a sign that the stock is set to drop as the stock moves back below the upper band and toward the middle band. You may want to consider selling the stock or exploring put options.
The Aroon Indicator for PASG entered a downward trend on November 06, 2026. This could indicate a strong downward move is ahead for the stock. Traders may want to consider selling the stock or buying put options.
The Tickeron Seasonality Score of 31 (best 1 - 100 worst) indicates that the company is slightly undervalued in the industry. The Tickeron Seasonality score describes the variance of predictable price changes around the same period every calendar year. These changes can be tied to a specific month, quarter, holiday or vacation period, as well as a meteorological or growing season.
The Tickeron Price Growth Rating for this company is 60 (best 1 - 100 worst), indicating steady price growth. PASG’s price grows at a higher rate over the last 12 months as compared to S&P 500 index constituents.
The Tickeron Valuation Rating of 69 (best 1 - 100 worst) indicates that the company is slightly overvalued in the industry. This rating compares market capitalization estimated by our proprietary formula with the current market capitalization. This rating is based on the following metrics, as compared to industry averages: P/B Ratio (2.870) is normal, around the industry mean (3.498). P/E Ratio (-0.351) is within average values for comparable stocks, (-1.193). Projected Growth (PEG Ratio) (0.000) is also within normal values, averaging (9.059). Dividend Yield (0.000) settles around the average of (130.658) among similar stocks. P/S Ratio (0.000) is also within normal values, averaging (440.869).
The Tickeron PE Growth Rating for this company is 99 (best 1 - 100 worst), pointing to worse than average earnings growth. The PE Growth rating is based on a comparative analysis of stock PE ratio increase over the last 12 months compared against S&P 500 index constituents.
The Tickeron SMR rating for this company is 99 (best 1 - 100 worst), indicating weak sales and an unprofitable business model. SMR (Sales, Margin, Return on Equity) rating is based on comparative analysis of weighted Sales, Income Margin and Return on Equity values compared against S&P 500 index constituents. The weighted SMR value is a proprietary formula developed by Tickeron and represents an overall profitability measure for a stock.
The Tickeron Profit vs. Risk Rating rating for this company is 100 (best 1 - 100 worst), indicating that the returns do not compensate for the risks. PASG’s unstable profits reported over time resulted in significant Drawdowns within these last five years. A stable profit reduces stock drawdown and volatility. The average Profit vs. Risk Rating rating for the industry is 94, placing this stock worse than average.
The average fundamental analysis ratings, where 1 is best and 100 is worst, are as follows
a genetic medicines company, which focuses on developing transformative therapies for rare, monogenic central nervous system disorders with limited or no approved treatment options
Industry Biotechnology