published in Blogs

Oct 31, 2018

Positive Cystic Fibrosis Data Shows Proteostasis (PTI) the Money

Proteostasis Therapeutics (PTI) is a small-cap company developing small molecule therapeutics to treat cystic fibrosis (CF) and other diseases caused by dysfunctional protein processing. Recently, the company announced positive preliminary results from its ongoing Phase 1 study of combination therapies for CF.

Cystic fibrosis (CF) is a progressive, genetic disease that causes persistent lung infections and limits the ability to breathe. More than 30,000 people in the US and greater than 70,000 worldwide live with the disease.

Each year approximately 1,000 new cases are diagnosed, according to the Cystic Fibrosis Foundation. Of those, more than 75% of patients diagnosed by age 2.

People with CF have a defective gene that causes a buildup of mucus in the lungs, pancreas, and other organs. Airways can become clogged causing respiratory failure and experience the blocking of digestive enzymes in the pancreas that can impair the body's ability to absorb vital nutrients

The combination treatments Proteostasis Therapeutics is developing showed improvement in the percent predicted forced expiratory volume and sweat chloride concentration across all cohorts. The improvement was significantly greater than the norm using the current standard of care.

The stock spiked significantly on this report and had been trading between $6 to $8. Proteostasis took advantage of its recent increase in share price to raise $74 million by pricing 11 million shares in a Form S-3 shelf registration.

Proteostasis is committed to developing novel therapeutics to treat diseases caused by an imbalance in the "proteostasis" or the protein homeostasis network set of biological pathways that control the creation, folding, transportation, maintenance and degradation of proteins in the body.

An imbalance in this network can lead to poor protein quality control contributing to diseases such as CF and gain-of-toxic function disorders like Alzheimer’s, Huntington’s and Parkinson’s diseases.

Proteostasis went public in 2016 with a market cap of under $200 million. The recent developments may provide astute investors with an opportunity to get on board and benefit from the growth of this exciting company that despite its success may still be a great value and growth opportunity.

Related Ticker: YMTX

Sergey Savastiouk

published in Blogs

Mar 14, 2023

How to Start Trading Penny Stocks

Penny stocks have long been marginalized within the professional investment community, oftentimes being painted with a broad brush of simply being “too risky.” Leonardo DiCaprio’s depiction of the penny stock peddling conman, Jordan Belfort, in the Wolf of Wall Street certainly didn’t help.Here are four reasons to start trading them now. Reason #1: Let’s State the Obvious -- Penny Stocks are Cheap A single share of Apple Inc. costs over $350.

Dmitry Perepelkin

published in Blogs

Mar 14, 2023

5 Habits that Lead to Successful Investing

To consistently make money in this industry, you need emotional fortitude, an analytical mind, and a willingness to self-reflect. Despite trading and investing being two different activities, these principles can be applied to both.Conversely, investors with good habits often become great traders. Rather than full sentences for titles, we’ve labeled each of our top-five investing habits using a single word principle.

Allana

published in Blogs

Mar 23, 2023

What’s the Difference Between Data Analytics and Machine Learning?

Artificial intelligence (AI) technology is developing rapidly.Data mining can deliver raw numbers, but it does not necessarily provide actionable insights. Structure is necessary to taking abstract information and extracting commonalities, like averages, ratios, and percentages.

Sergey Savastiouk

published in Blogs

Mar 13, 2023

4 Tips for Fast, Effective Stock Analysis

With just a few clicks, an investor can search for individual stocks, categories of stocks, sectors, or investment themes, and then he or she can conduct a full range of technical and fundamental analysis within seconds.All powered by Artificial Intelligence. Below, we give you 5 tips for fast, effective stock analysis using Tickeron’s Screener.

Sergey Savastiouk

published in Blogs

Mar 20, 2023

5 Golden Principles in Investing

You have enough faith in that stock, based on research, that the return will equal or exceed the investment. Do unto others.The principles outlined here will ensure that happens. Principle #1: Diversification Investors can’t be one-dimensional when constructing a portfolio.

John Jacques

published in Blogs

Mar 24, 2023

If Hedge Funds are Using AI to Invest, Why Shouldn’t You?

Some of the world’s biggest financial institutions have devoted multi-million dollar budgets to developing algorithms that can find patterns in the market, identify trends, and perform automated trading designed to take advantage of even the smallest price movements. The AI revolution is so big that as it stands today, the world’s five biggest hedge funds all use systems-based approaches to trade financial markets.Indeed, quantitative trading hedge funds now manage $918 billion (according to HFR), which amounts to 30% of the $3 trillion hedge fund industry – a percentage continues to grow with each year that passes.

Sergey Savastiouk

published in Blogs

Mar 15, 2023

The five most important Lessons Learned After 10,000 hours of Trading

Ten thousand hours of active trading, broken down into forty-hour weeks, amounts to almost five years. Having surpassed that milestone myself, I now understand why it's significant for any trader's journey. The early years taught me valuable lessons that have shaped my approach to trading. It's a misconception that great traders are born with innate talent. The truth is that it takes years of...

Edward Flores

published in Blogs

Mar 12, 2023

What's the Difference Between Tokens and Altcoins?

Between their inherently technical nature, multiple varieties and sub-varieties, and endless terminology, cryptocurrency (defined here as digital or virtual currencies that are encrypted using cryptography, powered by the immutable digital ledger known as the blockchain) represents a whole, complex world.All altcoins possess their own blockchain, independent from their source code, that records all transactions of their native coins. Many altcoins are variants, or forks, of Bitcoin that leverage that cryptocurrency’s open-source protocol as the basis.

Edward Flores

published in Blogs

Mar 26, 2023

Why it Pays to Invest in Dividend Stocks Over the Long Term

Where smaller, more volatile companies can placate shareholders with higher returns, larger companies often use dividend payouts to entice new investors and hold their existing ones. These low-risk options may not work for every investment approach, but dividend-producing stocks can offer great benefits under the right circumstances – especially for portfolios built for the long-term.Beyond the ability to rely on these semi-regular payouts as an income stream – a strategy favored by retirees – dividends are an excellent vehicle for compounding earnings through reinvestment.

Edward Flores

published in Blogs

Apr 02, 2023

How Artificial Intelligence Can Improve Fintech

Artificial intelligence (AI) and fintech have an inherent compatibility that has become clearer as each sector has matured, with recent growth and successes on their own accord bringing new ideas about how they can work together.AI can analyze information at far greater quantities (and far more quickly) than any human, making it a natural fit to help fintech firms streamline and automate processes that benefit customers and businesses alike. Fintech has brought a revolution of convenience to the finance world.