GKOS
Price
$163.67
Change
+$0.50 (+0.31%)
Updated
Oct 2, 04:59 PM (EDT)
Capitalization
9.35B
33 days until earnings call
Intraday BUY SELL Signals
ISRG
Price
$391.94
Change
-$9.30 (-2.32%)
Updated
Oct 2, 04:59 PM (EDT)
Capitalization
146.54B
18 days until earnings call
Intraday BUY SELL Signals
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GKOS vs ISRG

GKOS vs ISRG Comparison Chart in %
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A.I.Advisor
Sep 21, 2026

Which Stock Would AI Choose? Glaukos Corporation (GKOS) vs. Intuitive Surgical, Inc. (ISRG) Stock Comparison

Key Takeaways

  • Glaukos Corporation (GKOS) has delivered stronger recent revenue growth and raised its full-year 2026 sales guidance following robust second-quarter results.
  • Intuitive Surgical, Inc. (ISRG) maintains a dominant position in robotic-assisted surgery but has faced moderating procedure growth and increased competition.
  • GKOS stock has shown notable year-to-date gains and trades near the upper end of its 52-week range, while ISRG has experienced a pullback from recent highs.
  • Both companies operate in the healthcare equipment sector with exposure to medical device innovation, though GKOS focuses on ophthalmology and ISRG on minimally invasive surgical systems.
  • Institutional interest in GKOS has increased, including new positions disclosed in recent filings, amid positive analyst sentiment.
  • Relative performance highlights trade-offs between GKOS’s higher-growth momentum profile and ISRG’s larger scale and established profitability.

Introduction

This comparison examines Glaukos Corporation (GKOS) and Intuitive Surgical, Inc. (ISRG), two healthcare equipment companies with distinct focuses within medical technology. GKOS specializes in ophthalmic therapies for glaucoma and corneal conditions, while ISRG leads in robotic-assisted surgical systems. The analysis is relevant for traders and investors seeking to understand relative performance, growth drivers, and market positioning in the current environment. It draws on recent market activity, financial metrics, and sector dynamics to provide a balanced view suitable for those evaluating opportunities in medical devices.

GKOS Overview and Recent Performance

Glaukos Corporation (GKOS) develops therapies and devices for glaucoma, corneal disorders, and related ophthalmic conditions. In recent market activity, the stock has demonstrated resilience and upward momentum, trading near the upper portion of its 52-week range after posting strong year-to-date gains. Second-quarter 2026 results showed record net sales with significant year-over-year increases, prompting the company to raise its full-year guidance. Factors influencing sentiment include strong uptake of key products such as iDose TR and Epioxa, alongside institutional accumulation noted in recent filings. Performance has been supported by execution across commercial and development priorities amid broader healthcare sector rotation.

ISRG Overview and Recent Performance

Intuitive Surgical, Inc. (ISRG) develops and markets robotic-assisted surgical systems, primarily the da Vinci platform, enabling minimally invasive procedures. Recent market activity has reflected a more measured trajectory, with the stock pulling back from prior highs amid signs of moderating U.S. procedure growth and emerging competition. Second-quarter 2026 results exceeded expectations on revenue and earnings, yet investor focus shifted toward the pace of adoption and forward outlook. Sentiment has been shaped by the company’s scale advantages and international expansion, tempered by competitive pressures in the robotic surgery space and broader valuation considerations in the healthcare equipment sector.

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Head-to-Head Comparison

Glaukos Corporation (GKOS) and Intuitive Surgical, Inc. (ISRG) differ markedly in scale, business focus, and financial profile. GKOS operates as a smaller-cap innovator in ophthalmology with rapid revenue expansion driven by new product launches, while ISRG commands a much larger market capitalization and benefits from established leadership in robotic surgery with more consistent profitability. Recent momentum favors GKOS through stronger year-to-date performance and guidance upgrades, whereas ISRG contends with slower procedure growth and competitive headwinds. Risk factors for GKOS include reimbursement uncertainty and ongoing losses, contrasted with ISRG’s exposure to capital equipment cycles and regulatory scrutiny. Sector exposure overlaps in healthcare equipment, yet GKOS offers higher-beta growth characteristics and ISRG provides greater stability tied to procedure volumes. Market sentiment reflects these contrasts, with GKOS attracting attention for its expansion trajectory and ISRG valued for its entrenched position despite near-term pressures.

Tickeron AI Verdict

Based on observable factors including trend consistency, revenue growth rates, and relative positioning in recent market activity, Tickeron’s AI would currently assign a probabilistic preference to Glaukos Corporation (GKOS). The stock’s stronger recent execution and momentum signals provide a more favorable profile under current conditions compared with Intuitive Surgical, Inc. (ISRG)’s moderating growth trajectory. This assessment remains probabilistic and subject to ongoing market developments.

Disclaimer

The information on this webpage is provided for general informational and educational purposes only and is not intended as investment advice, a recommendation to purchase or sell any security, or an offer or solicitation related to investments. It does not consider your personal financial situation, goals, or risk profile, and all investing carries inherent risks, including the possibility of losing your entire investment. For more details, please review our full disclaimer.

Disclaimers and Limitations

VS
GKOS vs. ISRG commentary
Oct 02, 2026

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is GKOS is a StrongBuy and ISRG is a Buy.

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SUMMARIES
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FUNDAMENTALS RATINGS
GKOS vs ISRG: Fundamental Ratings
GKOS
ISRG
OUTLOOK RATING
1..100
8037
VALUATION
overvalued / fair valued / undervalued
1..100
95
Overvalued
76
Overvalued
PROFIT vs RISK RATING
1..100
4087
SMR RATING
1..100
9651
PRICE GROWTH RATING
1..100
3853
P/E GROWTH RATING
1..100
4666
SEASONALITY SCORE
1..100
3985

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

ISRG's Valuation (76) in the Medical Specialties industry is in the same range as GKOS (95). This means that ISRG’s stock grew similarly to GKOS’s over the last 12 months.

GKOS's Profit vs Risk Rating (40) in the Medical Specialties industry is somewhat better than the same rating for ISRG (87). This means that GKOS’s stock grew somewhat faster than ISRG’s over the last 12 months.

ISRG's SMR Rating (51) in the Medical Specialties industry is somewhat better than the same rating for GKOS (96). This means that ISRG’s stock grew somewhat faster than GKOS’s over the last 12 months.

GKOS's Price Growth Rating (38) in the Medical Specialties industry is in the same range as ISRG (53). This means that GKOS’s stock grew similarly to ISRG’s over the last 12 months.

GKOS's P/E Growth Rating (46) in the Medical Specialties industry is in the same range as ISRG (66). This means that GKOS’s stock grew similarly to ISRG’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
GKOSISRG
RSI
ODDS (%)
Bullish Trend 2 days ago
85%
Bearish Trend 2 days ago
29%
Stochastic
ODDS (%)
Bullish Trend 2 days ago
87%
Bearish Trend 2 days ago
52%
Momentum
ODDS (%)
Bullish Trend 2 days ago
88%
Bullish Trend 2 days ago
68%
MACD
ODDS (%)
N/A
Bullish Trend 2 days ago
61%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
79%
Bullish Trend 2 days ago
64%
TrendMonth
ODDS (%)
Bearish Trend 2 days ago
66%
Bullish Trend 2 days ago
64%
Advances
ODDS (%)
Bullish Trend 18 days ago
78%
Bullish Trend 5 days ago
67%
Declines
ODDS (%)
Bearish Trend 10 days ago
67%
Bearish Trend 2 days ago
61%
BollingerBands
ODDS (%)
Bullish Trend 2 days ago
79%
Bearish Trend 2 days ago
44%
Aroon
ODDS (%)
Bearish Trend 2 days ago
63%
Bearish Trend 2 days ago
71%
COMPARISON
Comparison
Oct 02, 2026
Stock price -- (GKOS: $163.17 vs. ISRG: $401.24)
Brand notoriety: GKOS: Not notable vs. ISRG: Notable
GKOS represents the Medical/Nursing Services, while ISRG is part of the Pharmaceuticals: Other industry
Current volume relative to the 65-day Moving Average: GKOS: 86% vs. ISRG: 62%
Market capitalization -- GKOS: $9.35B vs. ISRG: $146.54B
GKOS [@Medical/Nursing Services] is valued at $9.35B. ISRG’s [@Pharmaceuticals: Other] market capitalization is $146.54B. The market cap for tickers in the [@Medical/Nursing Services] industry ranges from $837 to $174.73B. The market cap for tickers in the [@Pharmaceuticals: Other] industry ranges from $126 to $146.54B. The average market capitalization across the [@Medical/Nursing Services] industry is $5.55B. The average market capitalization across the [@Pharmaceuticals: Other] industry is $8.89B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is overvalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

GKOS’s FA Score shows that 0 FA rating(s) are green while ISRG’s FA Score has 0 green FA rating(s).

  • GKOS’s FA Score: 0 green, 5 red.
  • ISRG’s FA Score: 0 green, 5 red.
According to our system of comparison, GKOS is a better buy in the long-term than ISRG.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

GKOS’s TA Score shows that 5 TA indicator(s) are bullish while ISRG’s TA Score has 5 bullish TA indicator(s).

  • GKOS’s TA Score: 5 bullish, 4 bearish.
  • ISRG’s TA Score: 5 bullish, 5 bearish.
According to our system of comparison, GKOS is a better buy in the short-term than ISRG.

Price Growth

GKOS (@Medical/Nursing Services) experienced а +5.35% price change this week, while ISRG (@Pharmaceuticals: Other) price change was +0.43% for the same time period.

The average weekly price growth across all stocks in the @Medical/Nursing Services industry was -2.15%. For the same industry, the average monthly price growth was -6.04%, and the average quarterly price growth was -2.68%.

The average weekly price growth across all stocks in the @Pharmaceuticals: Other industry was -2.26%. For the same industry, the average monthly price growth was -5.19%, and the average quarterly price growth was +14.13%.

Reported Earning Dates

GKOS is expected to report earnings on Nov 04, 2026.

ISRG is expected to report earnings on Oct 20, 2026.

Industries' Descriptions

@Medical/Nursing Services (-2.15% weekly)

The medical/nursing services includes companies that provide medical-related services such as ambulance services, dialysis centers, respiratory therapy, blood testing and rehabilitation services. DaVita Inc., Chemed Corporation and Guardant Health, Inc. are examples of companies in this industry.

@Pharmaceuticals: Other (-2.26% weekly)

Pharmaceuticals (Other) comprise companies that are involved in the discovery, development or manufacturing of therapeutic and preventative medicines. They often collaborate with or acquire other pharmaceutical/healthcare firms. Examples of companies in this segment include Bausch Health Companies Inc., Icon Plc and Perrigo Company Plc.

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GKOS
Daily Signal:
Gain/Loss:
ISRG
Daily Signal:
Gain/Loss:
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GKOS and

Correlation & Price change

A.I.dvisor indicates that over the last year, GKOS has been loosely correlated with ISRG. These tickers have moved in lockstep 51% of the time. This A.I.-generated data suggests there is some statistical probability that if GKOS jumps, then ISRG could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To GKOS
1D Price
Change %
GKOS100%
-0.62%
ISRG - GKOS
51%
Loosely correlated
-1.33%
NTRA - GKOS
48%
Loosely correlated
-1.17%
RDNT - GKOS
48%
Loosely correlated
-1.80%
TWST - GKOS
46%
Loosely correlated
-2.69%
ALGN - GKOS
43%
Loosely correlated
-0.00%
More

ISRG and

Correlation & Price change

A.I.dvisor indicates that over the last year, ISRG has been closely correlated with BSX. These tickers have moved in lockstep 73% of the time. This A.I.-generated data suggests there is a high statistical probability that if ISRG jumps, then BSX could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To ISRG
1D Price
Change %
ISRG100%
-1.33%
BSX - ISRG
73%
Closely correlated
-0.96%
SYK - ISRG
64%
Loosely correlated
-0.88%
NTRA - ISRG
54%
Loosely correlated
-1.17%
GKOS - ISRG
51%
Loosely correlated
-0.62%
PODD - ISRG
49%
Loosely correlated
+0.25%
More