Genmab is a Copenhagen-based biotechnology company specializing in antibody therapeutics for the treatment of cancer... Show more
Genmab A/S is a Copenhagen, Denmark-based biotechnology company founded in 1999 that specializes in discovering and developing antibody-based therapies for cancer and other serious diseases. Its technology platforms span bispecific antibodies, antibody-drug conjugates, and effector function-enhanced antibodies. The company's economics are anchored by royalty streams from partnered blockbusters, most notably DARZALEX (daratumumab), alongside wholly owned commercial products such as EPKINLY/TEPKINLY (epcoritamab) and Tivdak (tisotumab vedotin). A network of collaborations with major pharmaceutical partners, including Johnson & Johnson (JNJ), AbbVie (ABBV), and Pfizer (PFE), lets Genmab capture value from global commercial infrastructure while advancing a deep internal pipeline. Its late-stage priorities center on EPKINLY, Rina-S (rinatabart sesutecan), and petosemtamab, an asset added through the roughly $8 billion acquisition of Merus.
Over the last 30 days, GMAB advanced approximately 61%, rising from a closing price of about $35.57 to roughly $57.28. The move accelerated sharply in late October, when shares surged about 30% in a single session to an all-time intraday high of $59.97 on October 28. The rally was accompanied by unusually heavy volume of more than 19 million shares, versus a three-month daily average near 4 million.
The quarterly trend was even stronger. From a closing level of roughly $28.52 three months earlier, the stock more than doubled, gaining about 101%. This reflects a sustained repricing of Genmab's pipeline rather than a single isolated event, as investors progressively rewarded positive clinical data across multiple programs.
The primary catalyst was the October 28 announcement of positive topline results from the global Phase 3 LiGeR-HN1 trial. The study evaluated petosemtamab in combination with pembrolizumab for first-line recurrent or metastatic head and neck cancer. Initial analysis showed a statistically significant and clinically meaningful improvement in overall survival versus pembrolizumab alone, with the combination reducing the risk of death by 50% and meeting its dual primary endpoints of overall survival and objective response rate.
This news built on an earlier data catalyst. On October 23, Genmab reported that the Phase 3 RAINFOL-02 trial of Rina-S in platinum-resistant ovarian cancer met both its primary progression-free survival endpoint and a key overall survival endpoint, with the drug cutting the risk of disease progression or death by 71% compared with chemotherapy. Following these readouts, JPMorgan upgraded Genmab to Overweight from Neutral and raised its price target, while TD Cowen lifted its target and reiterated a Buy rating. Analysts also cited petosemtamab as a central long-term growth driver for the company.
The quarterly doubling of GMAB shares reflects a broader narrative of pipeline validation and strategic repositioning. Through 2026, management has framed the year as "catalyst-heavy," with registrational readouts expected across EPKINLY, Rina-S, and petosemtamab and potential launches in 2027. The completed Merus acquisition expanded Genmab's late-stage portfolio and accelerated its shift toward a wholly owned commercial model, while the company continues to benefit from durable DARZALEX royalties and growing EPKINLY and Tivdak sales. Positive data in ovarian and head and neck cancer during the period de-risked key programs and prompted analysts to raise forward-looking peak-sales estimates, contributing to the stock's steep upward trajectory.
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Looking ahead, investors are likely to focus on the final analysis of the LiGeR-HN1 trial and Genmab's regulatory engagement for petosemtamab, along with the full Rina-S data set. Upcoming earnings releases, updates to 2026 guidance, and additional Phase 3 readouts for EPKINLY across earlier lines of diffuse large B-cell lymphoma will also be closely watched. Key risks include clinical or regulatory setbacks, competitive pressure in oncology, reliance on partner royalty streams such as DARZALEX, and the elevated valuation that now reflects high pipeline expectations. As with any biotechnology name, trial outcomes and regulatory decisions remain the dominant swing factors for the share price.
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The Stochastic Oscillator for GMAB moved out of overbought territory on November 06, 2026. This could be a bearish sign for the stock and investors may want to consider selling or taking a defensive position. A.I.dvisor looked at 58 similar instances where the indicator exited the overbought zone. In 42 of the 58 cases the stock moved lower. This puts the odds of a downward move at 72%.
The 10-day RSI Indicator for GMAB moved out of overbought territory on November 10, 2026. This could be a bearish sign for the stock. Traders may want to consider selling the stock or buying put options. Tickeron's A.I.dvisor looked at 41 similar instances where the indicator moved out of overbought territory. In 23 of the 41 cases, the stock moved lower in the following days. This puts the odds of a move lower at 56%.
Following a 3-day decline, the stock is projected to fall further. Considering past instances where GMAB declined for three days, the price rose further in 50 of 62 cases within the following month. The odds of a continued downward trend are 70%.
GMAB broke above its upper Bollinger Band on October 28, 2026. This could be a sign that the stock is set to drop as the stock moves back below the upper band and toward the middle band. You may want to consider selling the stock or exploring put options.
The Moving Average Convergence Divergence (MACD) for GMAB just turned positive on October 19, 2026. Looking at past instances where GMAB's MACD turned positive, the stock continued to rise in 28 of 43 cases over the following month. The odds of a continued upward trend are 65%.
Following a +5.80% 3-day Advance, the price is estimated to grow further. Considering data from situations where GMAB advanced for three days, in 200 of 308 cases, the price rose further within the following month. The odds of a continued upward trend are 65%.
The Aroon Indicator entered an Uptrend today. In 149 of 213 cases where GMAB Aroon's Indicator entered an Uptrend, the price rose further within the following month. The odds of a continued Uptrend are 70%.
The Tickeron PE Growth Rating for this company is 3 (best 1 - 100 worst), pointing to outstanding earnings growth. The PE Growth rating is based on a comparative analysis of stock PE ratio increase over the last 12 months compared against S&P 500 index constituents.
The Tickeron Price Growth Rating for this company is 34 (best 1 - 100 worst), indicating steady price growth. GMAB’s price grows at a higher rate over the last 12 months as compared to S&P 500 index constituents.
The Tickeron Seasonality Score of 50 (best 1 - 100 worst) indicates that the company is fair valued in the industry. The Tickeron Seasonality score describes the variance of predictable price changes around the same period every calendar year. These changes can be tied to a specific month, quarter, holiday or vacation period, as well as a meteorological or growing season.
The Tickeron SMR rating for this company is 59 (best 1 - 100 worst), indicating strong sales and a profitable business model. SMR (Sales, Margin, Return on Equity) rating is based on comparative analysis of weighted Sales, Income Margin and Return on Equity values compared against S&P 500 index constituents. The weighted SMR value is a proprietary formula developed by Tickeron and represents an overall profitability measure for a stock.
The Tickeron Profit vs. Risk Rating rating for this company is 74 (best 1 - 100 worst), indicating that the returns do not compensate for the risks. GMAB’s unstable profits reported over time resulted in significant Drawdowns within these last five years. A stable profit reduces stock drawdown and volatility. The average Profit vs. Risk Rating rating for the industry is 93, placing this stock better than average.
The Tickeron Valuation Rating of 93 (best 1 - 100 worst) indicates that the company is significantly overvalued in the industry. This rating compares market capitalization estimated by our proprietary formula with the current market capitalization. This rating is based on the following metrics, as compared to industry averages: P/B Ratio (5.536) is normal, around the industry mean (3.498). P/E Ratio (41.866) is within average values for comparable stocks, (-1.193). Projected Growth (PEG Ratio) (4.454) is also within normal values, averaging (9.059). Dividend Yield (0.000) settles around the average of (130.981) among similar stocks. P/S Ratio (5.192) is also within normal values, averaging (440.869).
The average fundamental analysis ratings, where 1 is best and 100 is worst, are as follows
an international biotechnology company, which develops human antibody therapeutics for the treatment of cancer and other diseases.
Industry Biotechnology