HeartFlow, Inc. is a commercial-stage medical technology company based in San Francisco that uses artificial intelligence and advanced computational fluid dynamics to deliver non-invasive solutions for diagnosing and managing coronary artery disease (CAD). Its HeartFlow One platform builds a personalized 3D model of a patient's coronary arteries from a single coronary computed tomography angiography (CCTA) image, and includes Roadmap Analysis, FFRCT Analysis, and Plaque Analysis software. The company has accumulated one of the world's largest databases of annotated cardiac CT images—more than 200 million images—and has helped guide care for over 650,000 patients worldwide. HeartFlow completed its initial public offering in August 2025 and generates the large majority of its revenue in the United States. I also checked this using Tickeron’s AI Screener to see how the stock compares to others in the industry.
Over the last 30 days, HTFL advanced roughly 92.9%, rising from a closing price near $25.37 in late July to about $48.94 by late August. Most of that move occurred in a matter of days after the company reported quarterly results, with shares jumping more than 35% in a single session and continuing to trade near 52-week highs afterward.
The quarterly picture tells a similar but more volatile story. Roughly three months earlier, the stock traded near $28, meaning it has gained on the order of 72% over the period. That broader trend was not linear: shares declined through much of July into the low-to-mid $20s before rebounding sharply once second-quarter results and revised guidance reset investor expectations.
The primary catalyst was HeartFlow's second-quarter 2026 earnings report. Revenue rose 48% year over year to approximately $64.1 million, ahead of the consensus estimate near $56.6 million, and adjusted loss per share of $0.07 was narrower than the roughly $0.13 loss analysts had expected. Gross margin reached record levels, expanding to 83.0% on a GAAP basis and 83.3% on a non-GAAP basis.
Management also raised its full-year 2026 revenue guidance to between $246 million and $250 million, up from a prior range of $228 million to $232 million, implying roughly 40% to 42% growth, and lifted its full-year gross margin target. Analysts responded by raising price targets—Stifel moved to $45 from $40 with a Buy rating, JPMorgan raised its target to $45 from $35 with an Overweight rating, and Wells Fargo increased its target to $39 from $37. William Blair's Brandon Vazquez maintained an Outperform rating, noting the guidance increase was roughly twice the size of the earnings beat. From what I see, this level of analyst support adds meaningful weight to the recent move.
Beyond the immediate earnings reaction, the stock's three-month advance reflects a broader narrative of accelerating adoption of AI-enabled cardiac diagnostics. HeartFlow's core FFRCT business has remained durable, while Plaque Analysis has emerged as a fast-growing second revenue engine following expanded reimbursement coverage. The company also launched PCI Navigator, an AI-driven pre-procedure planning tool for interventional cardiologists, and has pointed to a substantially under-penetrated CCTA market as a source of continued growth.
Institutional participation has also increased. According to third-party data, the number of hedge funds holding HeartFlow shares rose from 16 to 25 between consecutive quarters, with combined holdings growing by more than half. At the same time, the stock remains unprofitable, and valuation has expanded alongside the rally, leaving the shares sensitive to any shortfall in adoption or reimbursement trends.
Looking ahead, investors are likely to focus on the pace of Plaque Analysis adoption, including the company's progress toward its target of roughly 1,200 active sites, and on whether FFRCT case volumes sustain their current growth. Reimbursement developments, new clinical data, and updates to full-year guidance will also matter, as will the company's path toward narrowing operating losses and reaching cash-flow profitability. Because the stock has re-rated sharply, execution against the raised revenue outlook and continued gross-margin expansion will be closely monitored, alongside any signs that adoption is slowing or that valuation has outrun fundamentals. I’m watching this closely as the next few quarters will test whether the momentum holds.
In my own research process, I occasionally review Tickeron’s Trending AI Robots page to see how automated strategies are performing across various tickers. It offers a focused look at top bots without requiring a full scan of every option available, which can provide a useful complement when evaluating names like this one.
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The 10-day RSI Oscillator for HTFL moved out of overbought territory on September 08, 2026. This could be a sign that the stock is shifting from an upward trend to a downward trend. Traders may want to look at selling the stock or buying put options. Tickeron's A.I.dvisor looked at 5 instances where the indicator moved out of the overbought zone. In 5 of the 5 cases the stock moved lower in the days that followed. This puts the odds of a move down at 90%.
The Stochastic Oscillator entered the overbought zone. Expect a price pull-back in the foreseeable future.
The Moving Average Convergence Divergence Histogram (MACD) for HTFL turned negative on September 04, 2026. This could be a sign that the stock is set to turn lower in the coming weeks. Traders may want to sell the stock or buy put options. Tickeron's A.I.dvisor looked at 9 similar instances when the indicator turned negative. In 7 of the 9 cases the stock turned lower in the days that followed. This puts the odds of success at 78%.
Following a 3-day decline, the stock is projected to fall further. Considering past instances where HTFL declined for three days, the price rose further in 50 of 62 cases within the following month. The odds of a continued downward trend are 81%.
The Momentum Indicator moved above the 0 level on September 18, 2026. You may want to consider a long position or call options on HTFL as a result. In 23 of 23 past instances where the momentum indicator moved above 0, the stock continued to climb. The odds of a continued upward trend are 90%.
The 10-day moving average for HTFL crossed bullishly above the 50-day moving average on August 14, 2026. This indicates that the trend has shifted higher and could be considered a buy signal. In 1 of 2 past instances when the 10-day crossed above the 50-day, the stock continued to move higher over the following month. The odds of a continued upward trend are 50%.
The 50-day moving average for HTFL moved above the 200-day moving average on August 14, 2026. This could be a long-term bullish signal for the stock as the stock shifts to an upward trend.
Following a +5.07% 3-day Advance, the price is estimated to grow further. Considering data from situations where HTFL advanced for three days, in 70 of 77 cases, the price rose further within the following month. The odds of a continued upward trend are 90%.
HTFL may jump back above the lower band and head toward the middle band. Traders may consider buying the stock or exploring call options.
The Aroon Indicator entered an Uptrend today. In 28 of 41 cases where HTFL Aroon's Indicator entered an Uptrend, the price rose further within the following month. The odds of a continued Uptrend are 68%.
The Tickeron Price Growth Rating for this company is 35 (best 1 - 100 worst), indicating steady price growth. HTFL’s price grows at a higher rate over the last 12 months as compared to S&P 500 index constituents.
The Tickeron Valuation Rating of 47 (best 1 - 100 worst) indicates that the company is fair valued in the industry. This rating compares market capitalization estimated by our proprietary formula with the current market capitalization. This rating is based on the following metrics, as compared to industry averages: P/B Ratio (15.773) is normal, around the industry mean (7.474). HTFL has a moderately low P/E Ratio (0.000) as compared to the industry average of (46.724). Projected Growth (PEG Ratio) (0.000) is also within normal values, averaging (2.134). Dividend Yield (0.000) settles around the average of (0.010) among similar stocks. HTFL's P/S Ratio (19.763) is slightly higher than the industry average of (6.065).
The Tickeron SMR rating for this company is 98 (best 1 - 100 worst), indicating weak sales and an unprofitable business model. SMR (Sales, Margin, Return on Equity) rating is based on comparative analysis of weighted Sales, Income Margin and Return on Equity values compared against S&P 500 index constituents. The weighted SMR value is a proprietary formula developed by Tickeron and represents an overall profitability measure for a stock.
The Tickeron PE Growth Rating for this company is 100 (best 1 - 100 worst), pointing to worse than average earnings growth. The PE Growth rating is based on a comparative analysis of stock PE ratio increase over the last 12 months compared against S&P 500 index constituents.
The Tickeron Profit vs. Risk Rating rating for this company is 100 (best 1 - 100 worst), indicating that the returns do not compensate for the risks. HTFL’s unstable profits reported over time resulted in significant Drawdowns within these last five years. A stable profit reduces stock drawdown and volatility. The average Profit vs. Risk Rating rating for the industry is 98, placing this stock worse than average.
The average fundamental analysis ratings, where 1 is best and 100 is worst, are as follows
Industry ServicestotheHealthIndustry