HeartFlow, Inc. (HTFL) is a medical technology company that provides AI-powered, non-invasive solutions for diagnosing and managing coronary artery disease. Its shares rallied sharply in early trading Thursday, rising $8.31, or about 26.8%, to $39.32, compared with a prior closing price of $31.01 on Wednesday. The move extended a strong pre-market surge and reflected an enthusiastic market reaction to second-quarter 2026 results released after Wednesday’s close, which beat revenue expectations and included raised full-year guidance.
HeartFlow (HTFL) reported second-quarter revenue of $64.1 million, up 48% year over year and above the consensus estimate of about $56.6 million. U.S. revenue rose 51% to $59.6 million, while international and other revenue reached $4.5 million. The company’s non-GAAP net loss narrowed to $5.8 million, or $0.07 per share, from $17.6 million, or $2.79 per share, in the same period a year earlier.
Management also raised its full-year 2026 revenue guidance to a range of $246 million to $250 million, implying growth of 40% to 42%, up from a prior outlook of $228 million to $232 million. The company increased its full-year non-GAAP gross margin guidance to approximately 82% and reiterated its target of reaching cash flow profitability by mid-2028.
A key driver of the quarter was HeartFlow’s Plaque Analysis business. Plaque revenue of $7.8 million represented about 12% of total revenue and came in roughly $4 million above the company’s expectations. Management said new account activations were ahead of plan and that coverage had reached about 78% of insured lives. The company raised its full-year Plaque revenue outlook to $29 million to $31 million and now expects approximately 1,250 activated Plaque accounts by year-end.
The core FFRCT business also contributed, with U.S. FFRCT revenue growing about 32% during the quarter. Gross margin expanded to 83.3%, up 770 basis points from 75.6% a year earlier, supported by volume leverage, AI-driven efficiencies, and a higher mix of high-margin Plaque revenue.
The earnings-driven stock move was amplified by a wave of analyst activity. Stifel raised its price target on HTFL to $45 from $40 and maintained a Buy rating, citing strength in both the Plaque and FFRCT businesses. J.P. Morgan maintained a Buy rating with a $45 price target, while Wells Fargo maintained a Buy rating with a $39 target. The analyst response reinforced the view that HeartFlow’s accelerating revenue growth and improving margins are gaining credibility on Wall Street.
The rally appeared to be company-specific rather than driven by broad market or sector action. Shares jumped more than 20% in pre-market trading and extended those gains after the opening bell, moving from Wednesday’s close of $31.01 to around $39.32 by mid-morning Thursday. Wednesday’s regular-session volume of roughly 1.07 million shares was more than double the prior nine-session average of about 425,000 shares, indicating elevated investor interest even before the earnings announcement. The stock also traded near the upper end of its 52-week range, approaching its 52-week high of $41.22.
Investors will now focus on whether HTFL can sustain its Plaque adoption momentum and deliver on its raised revenue and margin guidance through the second half of 2026. Key catalysts include continued account activations, reimbursement developments, the DECIDE one-year outcomes expected in the fourth quarter, and broader evidence supporting expansion into the asymptomatic patient market. Risks include an ongoing competitive and regulatory environment, persistent GAAP losses, and a premium valuation that leaves the shares sensitive to any execution shortfall.
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The Stochastic Oscillator for HTFL moved out of overbought territory on September 23, 2026. This could be a bearish sign for the stock and investors may want to consider selling or taking a defensive position. A.I.dvisor looked at 12 similar instances where the indicator exited the overbought zone. In 12 of the 12 cases the stock moved lower. This puts the odds of a downward move at 90%.
The 10-day RSI Indicator for HTFL moved out of overbought territory on September 08, 2026. This could be a bearish sign for the stock. Traders may want to consider selling the stock or buying put options. Tickeron's A.I.dvisor looked at 5 similar instances where the indicator moved out of overbought territory. In 3 of the 5 cases, the stock moved lower in the following days. This puts the odds of a move lower at 60%.
The Moving Average Convergence Divergence Histogram (MACD) for HTFL turned negative on September 04, 2026. This could be a sign that the stock is set to turn lower in the coming weeks. Traders may want to sell the stock or buy put options. Tickeron's A.I.dvisor looked at 9 similar instances when the indicator turned negative. In 7 of the 9 cases the stock turned lower in the days that followed. This puts the odds of success at 78%.
Following a 3-day decline, the stock is projected to fall further. Considering past instances where HTFL declined for three days, the price rose further in 50 of 62 cases within the following month. The odds of a continued downward trend are 82%.
HTFL broke above its upper Bollinger Band on October 05, 2026. This could be a sign that the stock is set to drop as the stock moves back below the upper band and toward the middle band. You may want to consider selling the stock or exploring put options.
The Momentum Indicator moved above the 0 level on October 05, 2026. You may want to consider a long position or call options on HTFL as a result. In 22 of 23 past instances where the momentum indicator moved above 0, the stock continued to climb. The odds of a continued upward trend are 90%.
Following a +6.75% 3-day Advance, the price is estimated to grow further. Considering data from situations where HTFL advanced for three days, in 74 of 82 cases, the price rose further within the following month. The odds of a continued upward trend are 90%.
The Aroon Indicator entered an Uptrend today. In 34 of 45 cases where HTFL Aroon's Indicator entered an Uptrend, the price rose further within the following month. The odds of a continued Uptrend are 76%.
The Tickeron Price Growth Rating for this company is 36 (best 1 - 100 worst), indicating steady price growth. HTFL’s price grows at a higher rate over the last 12 months as compared to S&P 500 index constituents.
The Tickeron Valuation Rating of 46 (best 1 - 100 worst) indicates that the company is fair valued in the industry. This rating compares market capitalization estimated by our proprietary formula with the current market capitalization. This rating is based on the following metrics, as compared to industry averages: P/B Ratio (15.528) is normal, around the industry mean (7.432). HTFL has a moderately low P/E Ratio (0.000) as compared to the industry average of (46.656). Projected Growth (PEG Ratio) (0.000) is also within normal values, averaging (2.133). Dividend Yield (0.000) settles around the average of (0.010) among similar stocks. HTFL's P/S Ratio (19.763) is slightly higher than the industry average of (6.065).
The Tickeron SMR rating for this company is 98 (best 1 - 100 worst), indicating weak sales and an unprofitable business model. SMR (Sales, Margin, Return on Equity) rating is based on comparative analysis of weighted Sales, Income Margin and Return on Equity values compared against S&P 500 index constituents. The weighted SMR value is a proprietary formula developed by Tickeron and represents an overall profitability measure for a stock.
The Tickeron PE Growth Rating for this company is 100 (best 1 - 100 worst), pointing to worse than average earnings growth. The PE Growth rating is based on a comparative analysis of stock PE ratio increase over the last 12 months compared against S&P 500 index constituents.
The Tickeron Profit vs. Risk Rating rating for this company is 100 (best 1 - 100 worst), indicating that the returns do not compensate for the risks. HTFL’s unstable profits reported over time resulted in significant Drawdowns within these last five years. A stable profit reduces stock drawdown and volatility. The average Profit vs. Risk Rating rating for the industry is 98, placing this stock worse than average.
The average fundamental analysis ratings, where 1 is best and 100 is worst, are as follows
Industry ServicestotheHealthIndustry