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Serhii Bondarenko's Avatar
published in Blogs
Aug 04, 2023

Booming Metabolic Sector Stocks: $ARDX, $ATXS, $CBAY, 1W +9.68% Growth

A Thematic Dive into the Metabolic Biotechnology Space

Theme Metabolic +9.68%   -  1W change 
Theme Metabolic -  $ARDX $ATXS $CBAY $ICPT $MDGL $RYTM $VKTX

Swing Trader, Long Only: Growth Model (Diversified)  Annualized Return   + 13%  and  Swing Trader: Business Model (TA&FA)  Annualized Return   + 12%

The Metabolic Biotechnology Theme

In the biotechnology sector, certain companies focus on the development of pharmaceuticals aimed at treating gastrointestinal and metabolic disorders, earning them the classification of 'metabolic'. These companies, which include Ardelyx Inc., PhaseBio Pharmaceuticals Inc., and Catabasis Pharmaceuticals Inc., manufacture drugs aimed at mitigating and treating metabolic diseases and their associated symptoms.

This week, the metabolic theme has seen a promising performance, delivering a weekly change of +9.68%. This includes a mix of seven stocks, specifically $ARDX, $ATXS, $CBAY, $ICPT, $MDGL, $RYTM, and $VKTX.

The Financial Performance of Key Tickers

Ardelyx Inc. ($ARDX)

Ardelyx, a specialized biopharmaceutical company, made notable gains this week, with a significant price jump of +5.26% and another +6.06% surge, making it a top weekly gainer. Additionally, the volume of Ardelyx stock soared, breaking records with a daily growth of 278% of the 65-Day Volume Moving Average.

Catabasis Pharmaceuticals Inc. ($CBAY)

On the other hand, Catabasis Therapeutics didn't perform as well this week. Its stock price dipped by -6.5%, positioning it as the top weekly loser. While the downtrend is anticipated to continue, it's essential to watch for any possible changes in this trajectory.

Astria Therapeutics ($ATXS)

Astria Therapeutics has made headlines with a remarkable surge in volume. The company saw a daily growth of 1,377% and 342% of the 65-Day Volume Moving Average on two separate occasions. This significant volume increase suggests high investor interest and trading activity.

Overall Market Performance

The average market capitalization of the companies in the metabolic theme is around 1.3 billion dollars, with the highest valuation held by $MDGL at 3.8 billion and the lowest held by $ATXS at 251.1 million. The average weekly price growth across the group was 6.01%, while the average weekly volume growth was 60.13%.

As for the overall biotechnology industry, the average market capitalization is 2.2 billion dollars. The average weekly price growth across all stocks in the Biotechnology Industry was -1%, with the average weekly volume growth at 30.65%.

Industry Highlights

Biotechnology involves genetic or protein engineering to produce treatments and preventive therapies. The industry, which includes notable companies like Regeneron Pharmaceuticals, Moderna, and Incyte Corp, is heavily invested in research and development, striving to discover innovative health solutions.

The industry has witnessed some fluctuations with average weekly, monthly, and quarterly price growths of -1%, -1.65%, and 12.16% respectively. On the other hand, volume growth has been moderately stable, with weekly, monthly, and quarterly figures standing at 30.65%, -16.83%, and -2.55% respectively.

Fundamental Analysis Ratings

The metabolic theme has the following average fundamental analysis ratings: a Valuation Rating of 69, a P/E Growth Rating of 93, a Price Growth Rating of 45, and an SMR Rating of 97. The seasonality score is 40.

Meanwhile, the biotechnology industry displays a different set of ratings: a Valuation Rating of 50, a P/E Growth Rating of 87, a Price Growth Rating of 58, and an SMR Rating of 93. The seasonality score is neutral at 0.

Despite some market volatility, the metabolic theme within the biotechnology industry offers intriguing opportunities for investors. With the industry's emphasis on continual R&D, it is a space that is always worth watching for its potential to yield innovative, life-saving treatments, and correspondingly, rewarding investment returns.

Related Ticker: ATXS, CBAY, ARDX, ICPT, MDGL, RYTM, VKTX

Aroon Indicator for ATXS shows an upward move is likely

ATXS's Aroon Indicator triggered a bullish signal on November 10, 2025. Tickeron's A.I.dvisor detected that the AroonUp green line is above 70 while the AroonDown red line is below 30. When the up indicator moves above 70 and the down indicator remains below 30, it is a sign that the stock could be setting up for a bullish move. Traders may want to buy the stock or look to buy calls options. A.I.dvisor looked at 189 similar instances where the Aroon Indicator showed a similar pattern. In of the 189 cases, the stock moved higher in the days that followed. This puts the odds of a move higher at .

Price Prediction Chart

Technical Analysis (Indicators)

Bullish Trend Analysis

The Momentum Indicator moved above the 0 level on November 26, 2025. You may want to consider a long position or call options on ATXS as a result. In of 94 past instances where the momentum indicator moved above 0, the stock continued to climb. The odds of a continued upward trend are .

Following a 3-day Advance, the price is estimated to grow further. Considering data from situations where ATXS advanced for three days, in of 263 cases, the price rose further within the following month. The odds of a continued upward trend are .

ATXS may jump back above the lower band and head toward the middle band. Traders may consider buying the stock or exploring call options.

Bearish Trend Analysis

The 10-day RSI Indicator for ATXS moved out of overbought territory on November 11, 2025. This could be a bearish sign for the stock. Traders may want to consider selling the stock or buying put options. Tickeron's A.I.dvisor looked at 28 similar instances where the indicator moved out of overbought territory. In of the 28 cases, the stock moved lower in the following days. This puts the odds of a move lower at .

The Stochastic Oscillator may be shifting from an upward trend to a downward trend. In of 53 cases where ATXS's Stochastic Oscillator exited the overbought zone, the price fell further within the following month. The odds of a continued downward trend are .

The Moving Average Convergence Divergence Histogram (MACD) for ATXS turned negative on November 03, 2025. This could be a sign that the stock is set to turn lower in the coming weeks. Traders may want to sell the stock or buy put options. Tickeron's A.I.dvisor looked at 46 similar instances when the indicator turned negative. In of the 46 cases the stock turned lower in the days that followed. This puts the odds of success at .

Following a 3-day decline, the stock is projected to fall further. Considering past instances where ATXS declined for three days, the price rose further in of 62 cases within the following month. The odds of a continued downward trend are .

The Tickeron Price Growth Rating for this company is (best 1 - 100 worst), indicating steady price growth. ATXS’s price grows at a higher rate over the last 12 months as compared to S&P 500 index constituents.

The Tickeron Seasonality Score of (best 1 - 100 worst) indicates that the company is fair valued in the industry. The Tickeron Seasonality score describes the variance of predictable price changes around the same period every calendar year. These changes can be tied to a specific month, quarter, holiday or vacation period, as well as a meteorological or growing season.

The Tickeron Valuation Rating of (best 1 - 100 worst) indicates that the company is slightly overvalued in the industry. This rating compares market capitalization estimated by our proprietary formula with the current market capitalization. This rating is based on the following metrics, as compared to industry averages: P/B Ratio (5.236) is normal, around the industry mean (27.316). P/E Ratio (0.000) is within average values for comparable stocks, (52.494). Projected Growth (PEG Ratio) (0.000) is also within normal values, averaging (1.898). Dividend Yield (0.000) settles around the average of (0.048) among similar stocks. P/S Ratio (1000.000) is also within normal values, averaging (323.945).

The Tickeron Profit vs. Risk Rating rating for this company is (best 1 - 100 worst), indicating that the returns do not compensate for the risks. ATXS’s unstable profits reported over time resulted in significant Drawdowns within these last five years. A stable profit reduces stock drawdown and volatility. The average Profit vs. Risk Rating rating for the industry is 93, placing this stock better than average.

The Tickeron SMR rating for this company is (best 1 - 100 worst), indicating weak sales and an unprofitable business model. SMR (Sales, Margin, Return on Equity) rating is based on comparative analysis of weighted Sales, Income Margin and Return on Equity values compared against S&P 500 index constituents. The weighted SMR value is a proprietary formula developed by Tickeron and represents an overall profitability measure for a stock.

The Tickeron PE Growth Rating for this company is (best 1 - 100 worst), pointing to worse than average earnings growth. The PE Growth rating is based on a comparative analysis of stock PE ratio increase over the last 12 months compared against S&P 500 index constituents.

Notable companies

The most notable companies in this group are Regeneron Pharmaceuticals (NASDAQ:REGN), Incyte Corp (NASDAQ:INCY), Exelixis (NASDAQ:EXEL), Moderna (NASDAQ:MRNA), Arrowhead Pharmaceuticals (NASDAQ:ARWR), Adaptive Biotechnologies Corp (NASDAQ:ADPT), Sarepta Therapeutics (NASDAQ:SRPT), Nektar Therapeutics (NASDAQ:NKTR), Novavax (NASDAQ:NVAX), Inovio Pharmaceuticals (NASDAQ:INO).

Industry description

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

Market Cap

The average market capitalization across the Biotechnology Industry is 2.22B. The market cap for tickers in the group ranges from 58 to 110.02B. VRTX holds the highest valuation in this group at 110.02B. The lowest valued company is SEELQ at 58.

High and low price notable news

The average weekly price growth across all stocks in the Biotechnology Industry was 7%. For the same Industry, the average monthly price growth was 1%, and the average quarterly price growth was 73%. KTTA experienced the highest price growth at 403%, while CLSD experienced the biggest fall at -85%.

Volume

The average weekly volume growth across all stocks in the Biotechnology Industry was -34%. For the same stocks of the Industry, the average monthly volume growth was -60% and the average quarterly volume growth was -17%

Fundamental Analysis Ratings

The average fundamental analysis ratings, where 1 is best and 100 is worst, are as follows

Valuation Rating: 50
P/E Growth Rating: 79
Price Growth Rating: 55
SMR Rating: 91
Profit Risk Rating: 93
Seasonality Score: 5 (-100 ... +100)
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ATXS
Daily Signal:
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published price charts
These past five trading days, the stock lost 0.00% with an average daily volume of 0 shares traded.The stock tracked a drawdown of 0% for this period. ATXS showed earnings on November 12, 2025. You can read more about the earnings report here.
A.I. Advisor
published General Information

General Information

a developer of new medicines for the treatment of cardiovascular, metabolic and inflammatory diseases

Industry Biotechnology

Profile
Fundamentals
Details
Industry
Biotechnology
Address
75 State Street
Phone
+1 617 349-1971
Employees
59
Web
https://www.astriatx.com
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