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published in Blogs
Sep 26, 2023

$MRNA, $ALNY, $BGNE, $LEGN, $RPRX, $ROIV fell by 5-8% over the week.

Over the past week, the stock market has continued to decline. Leading the decline are biotechnology company stocks, which have fallen by 5-8%. You can receive signals for these company stocks by subscribing to our robots: Swing-trader-Downtrend-Protection-v-2-TA.

Notable Companies

Some of the most prominent companies in the Biotechnology industry include:

  1. Regeneron Pharmaceuticals (NASDAQ: REGN)
  2. Moderna (NASDAQ: MRNA)
  3. Incyte Corp (NASDAQ: INCY)
  4. Sarepta Therapeutics (NASDAQ: SRPT)
  5. Exelixis (NASDAQ: EXEL)
  6. Arrowhead Pharmaceuticals (NASDAQ: ARWR)
  7. BioCryst Pharmaceuticals (NASDAQ: BCRX)
  8. Adaptive Biotechnologies Corp (NASDAQ: ADPT)
  9. Novavax (NASDAQ: NVAX)
  10. Sorrento Therapeutics (OTC: SRNEQ)

Industry Description

Biotechnology is a diverse field that involves genetic and protein engineering to develop medications and therapies for the treatment and prevention of various medical conditions. Additionally, the industry plays a crucial role in producing essential components for diagnostic purposes. It's a multi-billion-dollar industry with a strong focus on research and development to innovate cutting-edge healthcare solutions.

Discoveries in the biotechnology sector have the potential for substantial growth. However, these breakthroughs must undergo rigorous regulatory approval processes, often by the U.S. Food and Drug Administration (FDA), before they can be introduced to the market. Some well-known companies in this industry include Amgen Inc., Gilead Sciences, Inc., and Celgene Corporation.

Market Capitalization

The average market capitalization within the Biotechnology industry is approximately $2.2 billion. Companies in this sector exhibit a wide range of market capitalization, spanning from $402 million to $410.2 billion. Notably, NVO holds the highest valuation in this group at $410.2 billion, while the lowest valued company is PNEXF at $402 million.

High and Low Price Notable News

Price fluctuations in the Biotechnology industry are quite dynamic. The average weekly price movement across all stocks in this sector was -3.83%. Over a monthly period, the average price growth was more positive at 22.16%, and for a quarter, it further increased to 34.16%. Among individual stocks, RNAZ experienced remarkable price growth at 335.08%, while SEEL faced a significant decline of -80.84%.

Some recent price highlights include:

  1. On 9/6/23 at 7:51 AM, Moderna (MRNA, $109.36) experienced a weekly decline of -5.72%, potentially indicating a trend reversal.
  2. On 8/25/23 at 7:08 AM, Moderna (MRNA, $112.65) showed a substantial weekly gain of +6.03%, suggesting a potential continuation of an uptrend.
  3. On 8/18/23 at 11:29 AM, Moderna (MRNA, $106.24) recorded a significant weekly gain of +5.94%.

Volume

The trading volume in the Biotechnology Industry is subject to fluctuations. On average, there was a weekly volume growth of 62.71% across all stocks in the industry. Over a month, the average volume growth was 135.64%, and for a quarter, it was 125.83%.

Some notable volume events include:

  1. On 9/16/23 at 7:44 AM, the volume for Roivant Sciences stock surged for one day, resulting in an extraordinary daily growth of 315% compared to the 65-Day Volume Moving Average.
  2. On 6/21/23 at 2:33 PM, Royalty Pharma's stock witnessed a consistent increase in volume for five consecutive days, with an average daily gain of 104%.

Fundamental Analysis Ratings

Fundamental analysis ratings help assess the overall health and performance of companies in the industry. These ratings are on a scale from 1 (best) to 100 (worst) and are as follows:

  • Valuation Rating: 50
  • P/E Growth Rating: 87
  • Price Growth Rating: 69
  • SMR Rating: 93
  • Profit Risk Rating: 95
  • Seasonality Score: -24 (on a scale of -100 to +100)

MRNA sees MACD Histogram crosses below signal line on September 19, 2023. This is a bearish signal, with an 85% chance of a downward move.

ALNY: The 10-day Moving Average crossed above the 50-day moving average on September 01, 2023, suggesting a 78% chance of an upward trend continuation.

BGNE: Broke above its upper Bollinger Band on August 29, 2023, indicating a 90% chance of a subsequent drop.

LEGN moved below its 50-day Moving Average on September 05, 2023, signaling a 90% chance of a continued downward trend.

RPRX: The Aroon Indicator entered a downward trend on September 15, 2023, with a 73% chance of a stock decline.

ROIV: The 10-day RSI Indicator moved out of overbought territory on September 11, 2023, implying a 78% chance of a downward trend.

Related Ticker: MRNA, ALNY, ONC, LEGN, RPRX, ROIV

MRNA in downward trend: 10-day moving average moved below 50-day moving average on November 05, 2025

The 10-day moving average for MRNA crossed bearishly below the 50-day moving average on November 05, 2025. This indicates that the trend has shifted lower and could be considered a sell signal. In of 11 past instances when the 10-day crossed below the 50-day, the stock continued to move higher over the following month. The odds of a continued downward trend are .

Price Prediction Chart

Technical Analysis (Indicators)

Bearish Trend Analysis

The Momentum Indicator moved below the 0 level on November 20, 2025. You may want to consider selling the stock, shorting the stock, or exploring put options on MRNA as a result. In of 83 cases where the Momentum Indicator fell below 0, the stock fell further within the subsequent month. The odds of a continued downward trend are .

The Moving Average Convergence Divergence Histogram (MACD) for MRNA turned negative on November 14, 2025. This could be a sign that the stock is set to turn lower in the coming weeks. Traders may want to sell the stock or buy put options. Tickeron's A.I.dvisor looked at 41 similar instances when the indicator turned negative. In of the 41 cases the stock turned lower in the days that followed. This puts the odds of success at .

MRNA moved below its 50-day moving average on November 13, 2025 date and that indicates a change from an upward trend to a downward trend.

Following a 3-day decline, the stock is projected to fall further. Considering past instances where MRNA declined for three days, the price rose further in of 62 cases within the following month. The odds of a continued downward trend are .

The Aroon Indicator for MRNA entered a downward trend on November 12, 2025. This could indicate a strong downward move is ahead for the stock. Traders may want to consider selling the stock or buying put options.

Bullish Trend Analysis

The Stochastic Oscillator is in the oversold zone. Keep an eye out for a move up in the foreseeable future.

Following a 3-day Advance, the price is estimated to grow further. Considering data from situations where MRNA advanced for three days, in of 268 cases, the price rose further within the following month. The odds of a continued upward trend are .

MRNA may jump back above the lower band and head toward the middle band. Traders may consider buying the stock or exploring call options.

The Tickeron PE Growth Rating for this company is (best 1 - 100 worst), pointing to outstanding earnings growth. The PE Growth rating is based on a comparative analysis of stock PE ratio increase over the last 12 months compared against S&P 500 index constituents.

The Tickeron Seasonality Score of (best 1 - 100 worst) indicates that the company is fair valued in the industry. The Tickeron Seasonality score describes the variance of predictable price changes around the same period every calendar year. These changes can be tied to a specific month, quarter, holiday or vacation period, as well as a meteorological or growing season.

The Tickeron Price Growth Rating for this company is (best 1 - 100 worst), indicating fairly steady price growth. MRNA’s price grows at a lower rate over the last 12 months as compared to S&P 500 index constituents.

The Tickeron Valuation Rating of (best 1 - 100 worst) indicates that the company is slightly overvalued in the industry. This rating compares market capitalization estimated by our proprietary formula with the current market capitalization. This rating is based on the following metrics, as compared to industry averages: P/B Ratio (1.013) is normal, around the industry mean (27.115). P/E Ratio (0.000) is within average values for comparable stocks, (51.613). Projected Growth (PEG Ratio) (0.000) is also within normal values, averaging (2.036). Dividend Yield (0.000) settles around the average of (0.047) among similar stocks. P/S Ratio (4.257) is also within normal values, averaging (317.729).

The Tickeron SMR rating for this company is (best 1 - 100 worst), indicating weak sales and an unprofitable business model. SMR (Sales, Margin, Return on Equity) rating is based on comparative analysis of weighted Sales, Income Margin and Return on Equity values compared against S&P 500 index constituents. The weighted SMR value is a proprietary formula developed by Tickeron and represents an overall profitability measure for a stock.

The Tickeron Profit vs. Risk Rating rating for this company is (best 1 - 100 worst), indicating that the returns do not compensate for the risks. MRNA’s unstable profits reported over time resulted in significant Drawdowns within these last five years. A stable profit reduces stock drawdown and volatility. The average Profit vs. Risk Rating rating for the industry is 94, placing this stock worse than average.

Notable companies

The most notable companies in this group are Regeneron Pharmaceuticals (NASDAQ:REGN), Incyte Corp (NASDAQ:INCY), Exelixis (NASDAQ:EXEL), Moderna (NASDAQ:MRNA), Arrowhead Pharmaceuticals (NASDAQ:ARWR), Adaptive Biotechnologies Corp (NASDAQ:ADPT), Sarepta Therapeutics (NASDAQ:SRPT), Nektar Therapeutics (NASDAQ:NKTR), Novavax (NASDAQ:NVAX), Inovio Pharmaceuticals (NASDAQ:INO).

Industry description

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

Market Cap

The average market capitalization across the Biotechnology Industry is 2.11B. The market cap for tickers in the group ranges from 58 to 107.15B. VRTX holds the highest valuation in this group at 107.15B. The lowest valued company is SEELQ at 58.

High and low price notable news

The average weekly price growth across all stocks in the Biotechnology Industry was -2%. For the same Industry, the average monthly price growth was -7%, and the average quarterly price growth was 60%. OLMA experienced the highest price growth at 177%, while TPST experienced the biggest fall at -58%.

Volume

The average weekly volume growth across all stocks in the Biotechnology Industry was -31%. For the same stocks of the Industry, the average monthly volume growth was -27% and the average quarterly volume growth was 65%

Fundamental Analysis Ratings

The average fundamental analysis ratings, where 1 is best and 100 is worst, are as follows

Valuation Rating: 50
P/E Growth Rating: 79
Price Growth Rating: 58
SMR Rating: 92
Profit Risk Rating: 93
Seasonality Score: 6 (-100 ... +100)
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MRNA
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These past five trading days, the stock lost 0.00% with an average daily volume of 0 shares traded.The stock tracked a drawdown of 0% for this period. MRNA showed earnings on November 06, 2025. You can read more about the earnings report here.
A.I. Advisor
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a developer of transformative medicines for patients

Industry Biotechnology

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Biotechnology
Address
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